Sex differences in correlates of suicide attempts in Chinese Han first‐episode and drug‐naïve major depressive disorder with comorbid subclinical hypothyroidism: A cross‐sectional study
Tian X, Liu X, Bai F, Li M, Qiu Y, Jiao Q, Li J, Zhang X. Sex differences in correlates of suicide attempts in Chinese Han first‐episode and drug‐naïve major depressive disorder with comorbid subclinical hypothyroidism: A cross‐sectional study. Brain And Behavior 2024, 14: e3578. PMID: 38844426, PMCID: PMC11156525, DOI: 10.1002/brb3.3578.Peer-Reviewed Original ResearchConceptsPositive and Negative Syndrome ScaleHamilton Depression ScaleHamilton Anxiety ScaleFEDN MDD patientsMDD patientsSuicide attemptsSex differencesDepressive disorderFirst-episodeFactors associated with suicide attemptsRisk of suicide attemptNegative Syndrome ScaleMajor depressive disorderHamilton Depression Scale scoresHamilton Anxiety Scale scoresThyroid peroxidase antibodySubclinical hypothyroidismIncreased suicide attemptsInvestigate sex differencesSignificant sex differencesSyndrome ScalePositive subscaleIncreased riskAnxiety ScaleFEDNGhrelin and depressive symptoms in patients with first‐episode drug‐naïve major depressive disorder: The mediating role of hypothalamic‐pituitary‐adrenal axis
Zhang C, Dong Y, Li S, Li M, Gao Y, Liu Y, Liu X, Zhou C, Li J. Ghrelin and depressive symptoms in patients with first‐episode drug‐naïve major depressive disorder: The mediating role of hypothalamic‐pituitary‐adrenal axis. Asia-Pacific Psychiatry 2024, 16: e12552. PMID: 38348641, DOI: 10.1111/appy.12552.Peer-Reviewed Original ResearchConceptsFirst-episode drug-naive MDD patientsMajor depressive disorderHAMD total scoreDrug-naive MDD patientsMDD patientsDepressive symptomsCorticotropin-releasing-hormoneTotal scoreDepressive disorderPathogenesis of major depressive disorderMeasures of depressive symptomsHealthy controlsHypothalamic-pituitary-adrenal axisHamilton Depression ScaleBody mass indexAdrenocorticotropic hormoneHAMD-17Plasma levels of ghrelinGhrelin levelsMediation analysisHAMDPartial correlation analysisDepression ScaleCortisol levelsLevels of ghrelin