2024
Association between peripheral plasma cytokine levels and suicidal ideation in first-episode, drug-naïve major depressive disorder
Tian X, Dong Y, Yuan J, Gao Y, Zhang C, Li M, Li J. Association between peripheral plasma cytokine levels and suicidal ideation in first-episode, drug-naïve major depressive disorder. Psychoneuroendocrinology 2024, 165: 107042. PMID: 38613945, DOI: 10.1016/j.psyneuen.2024.107042.Peer-Reviewed Original ResearchBeck Scale for Suicide Ideation-Chinese VersionChildhood Trauma QuestionnaireSuicidal ideationMDD patientsDepressive disorderFirst-episode drug-naive MDD patientsHamilton Depression Rating Scale-17Drug-naive MDD patientsIL-2 levelsMajor depressive disorderIL-2Plasma levelsIL-10HAMD-17First-episodeChildhood traumaTrauma QuestionnaireIL-8IL-6Plasma IL-2 levelsSuicide riskPlasma levels of cytokinesHAMA-14Stratified analysisIdeation
2023
Autophagy markers, cognitive deficits and depressive symptoms in Parkinson’s disease
Li Y, Yang H, Zhao P, Yang J, Yao C, Zhou C, Yang C, Sun X, Li S, Li J. Autophagy markers, cognitive deficits and depressive symptoms in Parkinson’s disease. Journal Of Neural Transmission 2023, 131: 73-81. PMID: 37801108, DOI: 10.1007/s00702-023-02702-w.Peer-Reviewed Original ResearchConceptsDepressed PD patientsDepressive symptomsNaming abilityPD patientsHamilton Depression Rating Scale-17Cognitive impairmentNon-depressed PD patientsLC3-II/LC3-IAssociated with delayed recallParkinson's diseaseAssociated with cognitive functionAssociated with MoCA scoresHAMD-17Cognitive deficitsMontreal Cognitive AssessmentDelayed recallCognitive functionCognitive AssessmentGlycolipid parametersAutophagy markersMoCA scoresSymptomsMotor functionImpairmentRecall
2021
Polymorphisms of COMT and CREB1 are associated with treatment-resistant depression in a Chinese Han population
Wang Y, Li S, Niu L, Ma Y, Qiu Y, Li S, Guobule N, Cao H, Li J. Polymorphisms of COMT and CREB1 are associated with treatment-resistant depression in a Chinese Han population. Journal Of Neural Transmission 2021, 129: 85-93. PMID: 34767111, DOI: 10.1007/s00702-021-02415-y.Peer-Reviewed Original ResearchConceptsTreatment-resistant depressionHamilton Depression Rating Scale-17Catechol-O-methyltransferaseCyclic AMP response element binding proteinRisk of treatment-resistant depressionPathophysiology of treatment-resistant depressionCREB1 geneAssociated with treatment-resistant depressionAssociated with antidepressant responseTreatment-resistant depressed patientsCatechol-O-methyltransferase rs4680Polymorphism of catechol-O-methyltransferaseCatechol-O-methyltransferase geneHDRS total scoreSymptoms of MDDNon-TRD groupAntidepressant responseAMP response element binding proteinDepressive disorderCREB1 polymorphismsDepressive symptomsTotal scoreSingle nucleotide polymorphismsGene-gene interaction effectsElement-binding proteinThe correlation of facial emotion recognition in patients with drug-naïve depression and suicide ideation
Wang Y, Guobule N, Li M, Li J. The correlation of facial emotion recognition in patients with drug-naïve depression and suicide ideation. Journal Of Affective Disorders 2021, 295: 250-254. PMID: 34482056, DOI: 10.1016/j.jad.2021.08.051.Peer-Reviewed Original ResearchConceptsMajor depressive disorderFacial emotion recognitionMajor depressive disorder patientsSuicidal ideationEmotion recognitionFirst-episodeSuicide riskBeck Scale for Suicide Ideation-Chinese VersionHamilton Depression Rating Scale-17Facial Emotion Recognition TestAssessment of Neuropsychological StatusRisk of suicidal behaviorDrug-naive outpatientsNeutral facial expressionsEmotion Recognition TestEpisodes of depressionPerceived social isolationHDRS-17Repeatable BatteryDepressive disorderSuicidal behaviorNeuropsychological statusFacial emotionsRecognition testDepressive symptoms