2007
A New Experimental Model of Isolated Perfused Pig Liver to Support Acute Hepatic Failure
Carraro A, Gringeri E, Calabrese F, Violi P, Brolese A, Zanus G, Boccagni P, Valente M, Bassi D, D’Amico F, D’Amico D, Cillo U. A New Experimental Model of Isolated Perfused Pig Liver to Support Acute Hepatic Failure. Transplantation Proceedings 2007, 39: 2028-2030. PMID: 17692683, DOI: 10.1016/j.transproceed.2007.05.070.Peer-Reviewed Original ResearchConceptsPerfused liver modelIsolated porcine liverLiver transplantationLiver failureAwaiting transplantationOrgan procurement ratesHepatic functionEffective treatmentEx vivo perfused liver modelPortal bloodHemodynamic homeostasisIsolated liverPerfused pig liverLiverLiver supportRecipient pigsTransplantationPatientsIsolated perfused pig liverLiver modelProcurement ratesMetabolic capacity
2003
Thermal homeostasis and liver transplantation.
D'Amico D, Vitale A, Cillo U, Boccagni P, Brolese A, Zanus G, Bassanello M, Montin U, Gringeri E, D'Amico F, Ciarleglio F, Cappuzzo G, Carraro A. Thermal homeostasis and liver transplantation. Acta BioMedica 2003, 74 Suppl 2: 30-3. PMID: 15055030.Peer-Reviewed Original ResearchConceptsGraft ischemia-reperfusion injuryGraft function recoveryPostoperative graft functionIschemia-reperfusion injuryInfluence of hypothermiaIntraoperative heat lossGraft functionLiver transplantationSevere hypothermiaCoagulation systemNormothermic oxygenated perfusionFunctional recoveryExtracorporeal circuitDonor poolAngiogenic mechanismsHypothermiaActive warmingOxygenated perfusionThermal homeostasisClinical researchGraftCardiovascular activityLiverDeleterious effectsHomeostasis