2016
Haptoglobin 2-2 Genotype Is Associated With Cerebral Salt Wasting Syndrome in Aneurysmal Subarachnoid Hemorrhage
Murthy S, Caplan J, Levy A, Pradilla G, Moradiya Y, Schneider E, Shalom H, Ziai W, Tamargo R, Nyquist P. Haptoglobin 2-2 Genotype Is Associated With Cerebral Salt Wasting Syndrome in Aneurysmal Subarachnoid Hemorrhage. Neurosurgery 2016, 78: 71-76. PMID: 26348010, DOI: 10.1227/neu.0000000000001000.Peer-Reviewed Original ResearchConceptsAneurysmal subarachnoid hemorrhageCerebral infarctionSubarachnoid hemorrhageHp genotypeHp 2Cerebral Salt Wasting SyndromeGlasgow Outcome ScoreCerebral saltUrine sodiumBaseline characteristicsSymptomatic vasospasmIndependent predictorsUrine outputClinical outcomesOutcome scoresSubsequent vasospasmFunctional outcomeProspective confirmationMultivariate regression modelGenotype testingHaptoglobin 2Haptoglobin genotypeOutcome measuresHemorrhagePatients
2014
Functional recovery after moderate/severe traumatic brain injury
Schneider E, Sur S, Raymont V, Duckworth J, Kowalski R, Efron D, Hui X, Selvarajah S, Hambridge H, Stevens R. Functional recovery after moderate/severe traumatic brain injury. Neurology 2014, 82: 1636-1642. PMID: 24759845, PMCID: PMC4211893, DOI: 10.1212/wnl.0000000000000379.Peer-Reviewed Original ResearchConceptsSevere traumatic brain injuryTraumatic brain injuryYears of educationBrain injuryDisability Rating Scale scoresProspective multicenter cohortMain outcome measuresRating Scale scoresRobust independent predictorModel Systems databaseDose-response relationshipLogistic regression modelsTBI Model Systems databaseCognitive reserveIndependent predictorsMulticenter cohortPrognostic factorsFunctional recoveryRetrospective studyDuration of educationYears postinjuryOutcome measuresPatientsScale scoreNeural adaptation
2012
Should the IDC-9 Trauma Mortality Prediction Model become the new paradigm for benchmarking trauma outcomes?
Haider A, Villegas C, Saleem T, Efron D, Stevens K, Oyetunji T, Cornwell E, Bowman S, Haack S, Baker S, Schneider E. Should the IDC-9 Trauma Mortality Prediction Model become the new paradigm for benchmarking trauma outcomes? Journal Of Trauma And Acute Care Surgery 2012, 72: 1695-1701. PMID: 22695443, DOI: 10.1097/ta.0b013e318256a010.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBenchmarkingCohort StudiesDatabases, FactualFemaleHospital MortalityHumansInternational Classification of DiseasesMaleMiddle AgedModels, StatisticalPredictive Value of TestsRetrospective StudiesSensitivity and SpecificityTrauma Severity IndicesTreatment OutcomeUnited StatesWounds and InjuriesYoung AdultConceptsInjury Severity ScoreNew ISSMortality prediction modelTrauma Mortality Prediction ModelTrauma outcomesInjury typeInjury severityNational Trauma Data BankNew Injury Severity ScoreInjury severity indicesMortality prediction abilityTrauma Data BankTrauma registry dataCrude mortality rateReceiver operator characteristic curveDRG International ClassificationOperator characteristic curveHospital mortalitySeverity scoreSubgroup analysisRegistry dataRetrospective analysisOutcome measuresPrognostic studiesInternational Classification
2011
Congestive Heart Failure and Chronic Obstructive Pulmonary Disease Predict Poor Surgical Outcomes in Older Adults Undergoing Elective Diverticulitis Surgery
Sheer AJ, Heckman JE, Schneider EB, Wu AW, Segal JB, Feinberg R, Lidor AO. Congestive Heart Failure and Chronic Obstructive Pulmonary Disease Predict Poor Surgical Outcomes in Older Adults Undergoing Elective Diverticulitis Surgery. Diseases Of The Colon & Rectum 2011, 54: 1430-1437. PMID: 21979190, DOI: 10.1097/dcr.0b013e31822c4e85.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCongestive heart failureObstructive pulmonary diseaseComorbid congestive heart failureHeart failurePulmonary diseaseHospital mortalityPostoperative complicationsOlder patientsElective surgeryOutcome measuresOlder adultsReview (MEDPAR) Inpatient FilesShock/sepsisRetrospective cohort studyPostoperative complication rateSecondary outcome measuresBenefits of surgeryPoor surgical outcomesPrimary outcome measureSubgroup of patientsAge 65 yearsLeft colon resectionCommon medical conditionsMedicare Provider Analysis