2002
Inhibition of Human CD4+CD25+high Regulatory T Cell Function
Baecher-Allan C, Viglietta V, Hafler DA. Inhibition of Human CD4+CD25+high Regulatory T Cell Function. The Journal Of Immunology 2002, 169: 6210-6217. PMID: 12444126, DOI: 10.4049/jimmunol.169.11.6210.Peer-Reviewed Original ResearchMeSH KeywordsAntigensCD4-Positive T-LymphocytesCoculture TechniquesCytokinesGlucocorticoid-Induced TNFR-Related ProteinHumansImmune ToleranceInterleukin-10Lymphocyte ActivationModels, ImmunologicalReceptors, Interleukin-2Receptors, Nerve Growth FactorReceptors, Tumor Necrosis FactorSignal TransductionT-Lymphocyte SubsetsTransforming Growth Factor betaConceptsAutoreactive T cellsT cellsRegulatory cellsRegulatory T cell functionInflammatory immune responseT cell functionStrength of stimulationPathologic responseInhibition of humanMicrobial AgsResponder cellsImmune responseEffector functionsTCR stimuliTime pointsCell functionTCR signalsPotent regulatorDifferential activationExtent of suppressionStimulationActivationCellsSuppressionStimuli
1994
Differential activation of cytolysis and proliferation in HTLV-I tax-reactive CD8 T cells by a single amino acid substitution in a T cell receptor contact residue of the peptide antigen
Höllsberg P, Weber W, Dangond F, Batra V, Sette A, Hafler D. Differential activation of cytolysis and proliferation in HTLV-I tax-reactive CD8 T cells by a single amino acid substitution in a T cell receptor contact residue of the peptide antigen. Journal Of Neuroimmunology 1994, 54: 168. DOI: 10.1016/0165-5728(94)90360-3.Peer-Reviewed Original Research