2021
Fibrinogen/Albumin Ratio as a Promising Marker for Predicting Survival in Pancreatic Neuroendocrine Neoplasms
Deng S, Fan Z, Xia H, Gong Y, Qian Y, Huang Q, Cheng H, Jin K, Xiao Z, Luo G, Yu X, Liu C. Fibrinogen/Albumin Ratio as a Promising Marker for Predicting Survival in Pancreatic Neuroendocrine Neoplasms. Cancer Management And Research 2021, 13: 107-115. PMID: 33447083, PMCID: PMC7802789, DOI: 10.2147/cmar.s275173.Peer-Reviewed Original ResearchProgression-free survivalFibrinogen/albumin ratioIndependent risk factorOverall survivalPoor OSPan-NENsCutoff valuePrognostic valueMultivariate analysisAssociated with poor OSRisk factorsGrade 3 tumorsStage IV tumorsOptimal cutoff valuePancreatic neuroendocrine neoplasmsNonfunctioning tumorsIV tumorsNeuroendocrine neoplasmsPrimary endpointSecondary endpointsPredictive biomarkersClinicopathological characteristicsPredicting prognosisUnivariate analysisPredicting survival
2020
Dynamics and Correlation Among Viral Positivity, Seroconversion, and Disease Severity in COVID-19
Fu Y, Li Y, Guo E, He L, Liu J, Yang B, Li F, Wang Z, Li Y, Xiao R, Liu C, Huang Y, Wu X, Lu F, You L, Qin T, Wang C, Li K, Wu P, Ma D, Sun C, Chen G. Dynamics and Correlation Among Viral Positivity, Seroconversion, and Disease Severity in COVID-19. Annals Of Internal Medicine 2020, 174: m20-3337. PMID: 33284684, PMCID: PMC7745119, DOI: 10.7326/m20-3337.Peer-Reviewed Original ResearchConceptsIndependent risk factorLaboratory-confirmed COVID-19Noncritically ill patientsViral positivityCritically ill patientsIll patientsDisease severityLow IgM titersRisk factorsViral polymerase chain reactionIgM titersCourse of coronavirus disease 2019Serum inflammatory markersIgM positive rateClinically diagnosed casesIgG positivity rateViral positivity rateMedian durationSpecialty care centersSeroconversion ratesAdult patientsInflammatory markersSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Polymerase chain reaction
2017
Epigenetic Regulations in the Pathogenesis of HCC and the Clinical Application
Puszyk W, Robertson K, Liu C. Epigenetic Regulations in the Pathogenesis of HCC and the Clinical Application. 2017, 69-93. DOI: 10.1007/978-3-319-68082-8_5.Peer-Reviewed Original ResearchNonalcoholic fatty liver diseaseDevelopment of hepatocellular carcinomaHepatocellular carcinoma casesHepatocellular carcinomaHepatitis B virusHepatitis C virusRisk factorsChronic infectionNonalcoholic steatohepatitisViral hepatocellular carcinomaChronic cigarette smokingIndependent risk factorPathogenesis of hepatocellular carcinomaConsumption of excess caloriesLiver cancer casesFatty liver diseaseProgress to nonalcoholic steatohepatitisExposure to environmental factorsHCC casesLiver malignanciesConsumption of alcoholCancer casesB virusC virusLiver disease
2009
NOD2 regulates hematopoietic cell function during graft-versus-host disease
Penack O, Smith O, Cunningham-Bussel A, Liu X, Rao U, Yim N, Na I, Holland A, Ghosh A, Lu S, Jenq R, Liu C, Murphy G, Brandl K, van den Brink M. NOD2 regulates hematopoietic cell function during graft-versus-host disease. Journal Of Experimental Medicine 2009, 206: 2101-2110. PMID: 19737867, PMCID: PMC2757869, DOI: 10.1084/jem.20090623.Peer-Reviewed Original ResearchConceptsAntigen-presenting cellsNOD2 deficiencyHost diseaseCrohn's diseaseExperimental allogeneic bone marrow transplantationAllogeneic bone marrow transplantationHost antigen-presenting cellsAllo-BMT recipientsDevelopment of GVHDExperimental colitis modelHematopoietic cellsHost hematopoietic cellsDonor T cellsIndependent risk factorBone marrow chimerasBone marrow transplantationChimeric recipientsIntestinal inflammationProinflammatory stateColitis modelMarrow transplantationNOD2 mutationsRisk factorsT cellsPaneth cells