1993
Dorsolateral prefrontal lesions and oculomotor delayed-response performance: evidence for mnemonic "scotomas"
Funahashi S, Bruce C, Goldman-Rakic P. Dorsolateral prefrontal lesions and oculomotor delayed-response performance: evidence for mnemonic "scotomas". Journal Of Neuroscience 1993, 13: 1479-1497. PMID: 8463830, PMCID: PMC6576716, DOI: 10.1523/jneurosci.13-04-01479.1993.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCuesEye MovementsMacaca mulattaMemoryOculomotor MusclesPrefrontal CortexReaction TimeSaccadesSpace PerceptionConceptsMemory-guided eye movementsPrefrontal lesionsPrefrontal cortexEye movementsDelay periodDelayed-response deficitsDorsolateral prefrontal lesionsDelayed-response performancePeripheral visual cuesDelayed-response paradigmFrontal eye field regionVisual field locationsSaccadic reaction timesUnilateral lesionsSpatial memory functionIpsilateral cuesMonkey prefrontal cortexODR taskOpposite hemifieldSpatial cuesVisual cuesSimple sensoryMemory mechanismsMemory deficitsVisual targets
1990
Primate frontal eye fields. III. Maintenance of a spatially accurate saccade signal
Goldberg M, Bruce C. Primate frontal eye fields. III. Maintenance of a spatially accurate saccade signal. Journal Of Neurophysiology 1990, 64: 489-508. PMID: 2213128, DOI: 10.1152/jn.1990.64.2.489.Peer-Reviewed Original ResearchConceptsFrontal eye fieldDouble-step taskSaccadic eye movementsEye fieldPostsaccadic activitySecond saccadeEye movementsFirst saccadeMonkey frontal eye fieldRetinal coordinatesDouble-step paradigmRetina. 2Receptive fieldsMovement fieldsVisuomovement cellsCell receptive fieldsPresaccadic activityMovement cellsFlashed targetsSaccade signalOculomotor tasksNeuronsSingle neuronsSaccadesRetinal stimulationVisuospatial coding in primate prefrontal neurons revealed by oculomotor paradigms
Funahashi S, Bruce C, Goldman-Rakic P. Visuospatial coding in primate prefrontal neurons revealed by oculomotor paradigms. Journal Of Neurophysiology 1990, 63: 814-831. PMID: 2341879, DOI: 10.1152/jn.1990.63.4.814.Peer-Reviewed Original ResearchConceptsODR taskVisual cuesPrefrontal cortexVisual responsesVisual probe taskLocation of cuesPrincipal sulcusVisual fieldDelay-period activitySame visual stimuliPrimate Prefrontal NeuronsDirectional visual responsesPassive visual responsesPS neuronsTask-related activityProbe taskSaccadic eye movementsVisuospatial codingCue locationSingle neuron activityVisual stimuliBehavioral enhancementOculomotor paradigmsPhasic visual responsesPrefrontal neurons
1988
Frontal eye field efferents in the macaque monkey: I. Subcortical pathways and topography of striatal and thalamic terminal fields
Stanton G, Goldberg M, Bruce C. Frontal eye field efferents in the macaque monkey: I. Subcortical pathways and topography of striatal and thalamic terminal fields. The Journal Of Comparative Neurology 1988, 271: 473-492. PMID: 2454970, DOI: 10.1002/cne.902710402.Peer-Reviewed Original ResearchMeSH KeywordsAmino AcidsAnimalsAutoradiographyBrain MappingCorpus StriatumEfferent PathwaysElectric StimulationEye MovementsHorseradish PeroxidaseMacacaMacaca fascicularisMacaca mulattaOculomotor MusclesThalamusVisual FieldsWheat Germ Agglutinin-Horseradish Peroxidase ConjugateWheat Germ AgglutininsConceptsFrontal eye fieldMedial dorsal nucleusTerminal fieldsInjection siteDorsal nucleusSubthalamic nucleusCaudate nucleusMacaque monkeysArea 6Thalamic terminal fieldsArea XSaccadic eye movementsAmplitude of saccadesPars parvicellularisSubthalamic pathwayInternal capsuleExternal capsuleThalamic nucleiAnterograde tracerVentrolateral partVentromedial partCaudate bodyDorsomedial portionSubcortical pathwaysCaudal partFrontal eye field efferents in the macaque monkey: II. Topography of terminal fields in midbrain and pons
Stanton G, Goldberg M, Bruce C. Frontal eye field efferents in the macaque monkey: II. Topography of terminal fields in midbrain and pons. The Journal Of Comparative Neurology 1988, 271: 493-506. PMID: 2454971, DOI: 10.1002/cne.902710403.Peer-Reviewed Original ResearchMeSH KeywordsAmino AcidsAnimalsAutoradiographyBrain MappingEfferent PathwaysElectric StimulationEye MovementsHorseradish PeroxidaseMacacaMesencephalonOculomotor MusclesPonsRaphe NucleiSuperior ColliculiTegmentum MesencephaliWheat Germ Agglutinin-Horseradish Peroxidase ConjugateWheat Germ AgglutininsConceptsPontine reticular formationSuperior colliculusReticular formationTerminal patchesAbducens nucleusTerminal fieldsMacaque monkeysIpsilateral nucleus prepositus hypoglossiLateral mesencephalic reticular formationParamedian pontine reticular formationLarge terminal fieldIpsilateral superior colliculusNucleus prepositus hypoglossiMesencephalic reticular formationRostral superior colliculusFibers of passagePatches of labelVentrolateral pontine reticular formationParvicellular red nucleusSaccadic eye movementsCaudal superior colliculusNucleus of DarkschewitschFEF projectionsNucleus limitansVentrolateral sites
1987
The role of striate cortex in the guidance of eye movements in the monkey
Segraves M, Goldberg M, Deng S, Bruce C, Ungerleider L, Mishkin M. The role of striate cortex in the guidance of eye movements in the monkey. Journal Of Neuroscience 1987, 7: 3040-3058. PMID: 3668615, PMCID: PMC6569180, DOI: 10.1523/jneurosci.07-10-03040.1987.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEye MovementsMacacaMacaca mulattaPsychomotor PerformanceReaction TimeSaccadesVisual CortexConceptsInitiation of saccadesCentral fixation pointLatency of saccadesSaccadic eye movementsStriate cortexSmooth pursuitEye velocityEye movementsImpaired fieldSmooth pursuit eye velocityFixation pointStep-ramp stimuliPursuit eye velocityIntact visual systemCortical ablationOculomotor abnormalitiesStimulus velocityFoveal targetAccurate saccadesStationary stimuliCortexSaccadesMonkeysVisual hemifieldLong latency
1986
The effect of attentive fixation on eye movements evoked by electrical stimulation of the frontal eye fields
Goldberg M, Bushnell M, Bruce C. The effect of attentive fixation on eye movements evoked by electrical stimulation of the frontal eye fields. Experimental Brain Research 1986, 61: 579-584. PMID: 3956616, DOI: 10.1007/bf00237584.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAttentionElectric StimulationEye MovementsFixation, OcularMacaca mulattaSaccadesVisual FieldsVisual PathwaysConceptsFrontal eye fieldEye fieldElectrical stimulationActive fixationAttentive fixationEye movementsVisual fixation targetBehavioral statesCerebral cortexEye velocityElicited saccadesLarge saccadesState of fixationFixation targetRhesus monkeysStimulating electrodesOculomotor systemEye positionSaccade amplitudeSaccadesVisual targetsStimulationMonkeysFixationResponsible factorsThe role of the arcuate frontal eye fields in the generation of saccadic eye movements
Goldberg M, Bruce C. The role of the arcuate frontal eye fields in the generation of saccadic eye movements. Progress In Brain Research 1986, 64: 143-154. PMID: 3726143, DOI: 10.1016/s0079-6123(08)63409-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArcuate Nucleus of HypothalamusDarknessEye MovementsMacaca mulattaPhotic StimulationSaccadesVisual Fields
1985
Primate frontal eye fields. II. Physiological and anatomical correlates of electrically evoked eye movements
Bruce C, Goldberg M, Bushnell M, Stanton G. Primate frontal eye fields. II. Physiological and anatomical correlates of electrically evoked eye movements. Journal Of Neurophysiology 1985, 54: 714-734. PMID: 4045546, DOI: 10.1152/jn.1985.54.3.714.Peer-Reviewed Original ResearchConceptsFrontal eye fieldEye fieldArcuate sulcusPresaccadic neuronsSaccade directionArea 8Frontal eye field neuronsEye movementsBrodmann area 8Cortical gray matterSaccadic eye movementsAwake macaque monkeysArea 8APresaccadic activityAnterior bankVentrolateral portionDorsomedial portionElicited saccadesElectrical stimulationLarge saccadesMacaque monkeysGray matterElectrode penetrationsAnatomical correlatesSmall saccades
1981
Visual experience and development of interocular orientation disparity in visual cortex.
Bruce C, Isley M, Shinkman P. Visual experience and development of interocular orientation disparity in visual cortex. Journal Of Neurophysiology 1981, 46: 215-228. PMID: 7264711, DOI: 10.1152/jn.1981.46.2.215.Peer-Reviewed Original Research
1977
Binocular Differences in Cortical Receptive Fields of Kittens After Rotationally Disparate Binocular Experience
Shinkman P, Bruce C. Binocular Differences in Cortical Receptive Fields of Kittens After Rotationally Disparate Binocular Experience. Science 1977, 197: 285-287. PMID: 877554, DOI: 10.1126/science.877554.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCatsDepth PerceptionEye MovementsOrientationVision, OcularVisual CortexVisual FieldsVisual Perception