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TZID:America/New_York
X-LIC-LOCATION:America/New_York
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DTSTART:20241103T020000
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TZNAME:EST
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DTSTART:20250309T020000
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DESCRIPTION:NOTE: You are invited to attend in person\, but may also atten
 d via Zoom. SPEAKER : Lee Kennedy-Shaffer\, PhD\, Assistant Professor\, D
 epartment of Mathematics & Statistics\, Vassar College TITLE : “Estimatin
 g Vaccine Efficacy Against Transmission: Statistical and Epidemiological 
 Challenges" ABSTRACT: Understanding how vaccines affect the future of an 
 infectious disease outbreak and public health more broadly requires an as
 sessment of how well they prevent infection and transmission in addition 
 to disease. While most vaccine trials use outcomes like symptomatic disea
 se\, we can use statistical\, epidemiological\, and biological understand
 ing to design studies that identify other aspects of vaccine performance.
  In this talk\, I will give an overview of trial designs that target thes
 e estimands and dive into our proposal to use viral load to estimate vacc
 ine efficacy against transmission\, detailing the statistical challenges 
 and epidemiological assumptions necessary. I also discuss the generalizab
 ility of these effect estimates as the epidemic progresses and changes an
 d policy questions that arise. These studies have an important role to pl
 ay alongside other designs in predicting and stopping epidemics. YSPH val
 ues inclusion and access for all participants. If you have questions abou
 t accessibility or would like to request an accommodation\, please contac
 t Charmila Fernandes at Charmila.fernandes@yale.edu . We will try to prov
 ide accommodations requested by December 6\, 2023.\n\nSpeaker:\nLee Kenne
 dy-Shaffer\, PhD\n\nAdmission:\nFree\n\nDetails URL:\nhttps://medicine.ya
 le.edu/event/ysph-biostatistics-seminar-tba-12-11-23-copy-4-copy/\n
DTEND;TZID=America/New_York:20231211T130000
DTSTAMP:20260506T060351Z
DTSTART;TZID=America/New_York:20231211T120000
GEO:41.302961;-72.931638
LOCATION:106-A\, 47 College Street\, New Haven\, CT\, United States
SEQUENCE:0
STATUS:Confirmed
SUMMARY:YSPH Biostatistics Seminar: “Estimating Vaccine Efficacy Against T
 ransmission: Statistical and Epidemiological Challenges"
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