Mapping metabolism with a Yale-developed imaging technique
Yale researchers have developed a new imaging technique that captures detailed information about metabolism, which plays a role in many diseases. The novel yet simple technique, which harnesses existing technology, could potentially be used to evaluate the effectiveness of drug therapies for cancer and other conditions, the researchers said.
Lower brain glucose levels found in people with obesity, type 2 diabetes
Glucose levels are reduced in the brains of individuals with obesity and type 2 diabetes compared to lean individuals, according to a new Yale study. The finding might explain disordered eating behavior — and even a higher risk of Alzheimer’s disease — among obese and diabetic individuals, the researchers said.
Yale launches five-year study of origins of autism
Yale researchers will study the development of functional brain connectivity during late pregnancy to early adolescence thanks to a five-year, $12.4 million grant from Autism Centers of Excellence Program, part of efforts by the National Institutes of Health to understand the origins of autism spectrum disorders (ASD).
Brain impairments in premature infants may begin in the womb
Even before they are born, premature babies may display alterations in the circuitry of their developing brains, according to a first-of-its kind research study by Yale School of Medicine researchers and their colleagues at the National Institutes of Health (NIH) and Wayne State University.
April is Alcohol Awareness Month
Whether it’s a single occasion or over a period of time, drinking too much can take a serious toll on your health. It can increase your risk of developing certain cancers and can damage or weaken your heart, liver, pancreas, and immune system. Yale conducts clinical research using the most advanced methods available to understand alcohol dependence and develop improved ways to treat it. April is Alcohol Awareness Month, an ideal time to consider participating in a research study.
Herold is New Chair of International Diabetes Consortium
Kevan C. Herold, MD, C.N.H. Long Professor of Immunobiology and professor of medicine (endocrinology) at Yale School of Medicine, has been named chair of Type 1 Diabetes (T1D) TrialNet, an international consortium dedicated to finding ways to prevent, delay, and slow progression of the disease.
Mavacamten Is Effective in Treating Obstructive Hypertrophic Cardiomyopathy
A new analysis of the EXPLORER-HCM study evaluating mavacamten, an investigational, first-in-class cardiac myosin inhibitor, in patients with obstructive hypertrophic cardiomyopathy (oHCM), found at 30 weeks improvement in the Kansas City Cardiomyopathy Questionnaire Overall Summary Score (KCCQ OSS) was greater in mavacamten patients than placebo.Source: DAIC
Outcomes Worse in Patients with Persistent Conduction Abnormalities after TAVR
Recent advances in TAVR have enabled lower-risk patients to benefit from this therapy. However, post-TAVR complications with the heart’s electrical impulses, known as conduction abnormalities, continue to undermine the next generation of valve repair devices.
Waterbury Black church leaders, Yale team up to dispel myths about COVID vaccine for communities of color, seniors
In Waterbury, an aggressive effort to take the COVID-19 vaccine to hard-to-reach communities embarked on another chapter Friday. This time, one of the city’s most popular Black churches engaged in something unique to shatter some vaccine myths.Source: WTNH