Mapping metabolism with a Yale-developed imaging technique
Yale researchers have developed a new imaging technique that captures detailed information about metabolism, which plays a role in many diseases. The novel yet simple technique, which harnesses existing technology, could potentially be used to evaluate the effectiveness of drug therapies for cancer and other conditions, the researchers said.
Lower brain glucose levels found in people with obesity, type 2 diabetes
Glucose levels are reduced in the brains of individuals with obesity and type 2 diabetes compared to lean individuals, according to a new Yale study. The finding might explain disordered eating behavior — and even a higher risk of Alzheimer’s disease — among obese and diabetic individuals, the researchers said.
Yale launches five-year study of origins of autism
Yale researchers will study the development of functional brain connectivity during late pregnancy to early adolescence thanks to a five-year, $12.4 million grant from Autism Centers of Excellence Program, part of efforts by the National Institutes of Health to understand the origins of autism spectrum disorders (ASD).
Brain impairments in premature infants may begin in the womb
Even before they are born, premature babies may display alterations in the circuitry of their developing brains, according to a first-of-its kind research study by Yale School of Medicine researchers and their colleagues at the National Institutes of Health (NIH) and Wayne State University.
April is Alcohol Awareness Month
Whether it’s a single occasion or over a period of time, drinking too much can take a serious toll on your health. It can increase your risk of developing certain cancers and can damage or weaken your heart, liver, pancreas, and immune system. Yale conducts clinical research using the most advanced methods available to understand alcohol dependence and develop improved ways to treat it. April is Alcohol Awareness Month, an ideal time to consider participating in a research study.
YSM Human Subjects Research Guidance Regarding COVID-19 (Novel Coronavirus) Pandemic
Our top priority remains the safety of our research participants, patients, staff, and faculty. We continue to monitor events to determine what actions are required to keep everyone safe and informed. As the university remains open, the HRPP and YCCI continuity plan for COVID 19 as of today will be to continue normal operations of administrative functions and clinical research resources unless a change is deemed necessary. Both offices will be staffed through a combination of social distancing, rotating schedules, and working remotely from home.
Update on Human Research during COVID-19
We are updating the policy and guidelines recently distributed for modification to our procedures for conducting human subject research at the School of Medicine due to the COVID-19 pandemic. This addendum to the guidelines does not change any underlying policies but updates procedures for the implementation of those policies. It recognizes the existence of several categories of research protocols that require different responses to accomplish our continuing goals. Our primary concern is the safety of our research participants and the research team members who work for YSM and the health system.
Addendum 03/16/2020 21:00 h
As we make decisions on how to respond to the COVID-19 infections we want to begin by re-stating that our primary concern is the safety of our research participants and the research team members who work for YSM and the Health System. Our secondary goal is to preserve the scientific integrity of the research protocols.
Guidance on Conduct of Human Research during COVID-19
We write to inform you of current policy and guidelines for modifications to our procedures for conducting human subject research at the School of Medicine due to the COVID-19 pandemic. These include modifications as well as information on what needs to be reported to the IRB.
Yale Scientists Awarded $8.4M Grant to Develop Treatments for Women With Problem Drinking
Yale Department of Psychiatry scientists have been awarded a five-year, $8.4 million federal grant to establish a new research center at Yale that will develop treatments to help women with problem drinking.
Less Leaflet Thrombosis in Low-Risk TAVR Patients Treated With Oral Anticoagulation
Oral anticoagulation with warfarin after TAVR in patients with severe, symptomatic aortic stenosis at low risk for surgery appears to provide early protection against subclinical thrombosis and does so without increasing the risk of bleeding or vascular complications, according to the results of a small study presented this week at CRT 2020.Source: TCTMD
Yale Genomics Study: Helping Researchers Better Understand the Opioid Epidemic
A human genomics study led by two Yale Department of Psychiatry researchers identified specific genetic regions that link opioid exposure and dependence to neuropsychiatric traits like risk-taking behaviors, alcohol abuse, and depression.