Yale Medicine Surgeons Use 3D Printing to Benefit Patients
Some Yale Medicine surgeons now routinely use 3D printing (essentially producing a solid, three-dimensional object from a virtual digital model) to plan surgeries, design tools specific to an upcoming surgery and that particular patient’s anatomy, and even to print some of the parts used to replace defective ones in the body.Source: Yale Medicine
Lower synaptic density is associated with depression severity and network alterations
Sophie Holmes, PhD, Associate Research Scientist, and Irina Esterlis, PhD, Associate Professor of Psychiatry, are the first and senior authors, respectively, of a study published in Nature Communications that examined synaptic density in 26 patients with major depressive disorder and post-traumatic stress disorder. The research revealed evidence linking lower synaptic density to network alterations and symptoms of depression.Source: Nature Communications
Connectome-based prediction of cocaine abstinence
Sarah Yip, PhD, MSc, Assistant Professor of Psychiatry, is the first author of a paper published in The American Journal of Psychiatry that tracks the results of a study that used connectome-based predictive modeling to identify neural networks predictive of future abstinence from cocaine.Source: The American Journal of Psychiatry
Mapping metabolism with a Yale-developed imaging technique
Yale researchers have developed a new imaging technique that captures detailed information about metabolism, which plays a role in many diseases. The novel yet simple technique, which harnesses existing technology, could potentially be used to evaluate the effectiveness of drug therapies for cancer and other conditions, the researchers said.
Cerebellar and prefrontal cortical alterations in PTSD: Structural and functional evidence
A Yale Department of Psychiatry and Yale School of Medicine paper published in Chronic Stress shows converging structural and functional evidence for cerebellum abnormalities in posttraumatic stress disorder. Sophie Holmes, PhD, Associate Research Scientist, is the first author.Source: Chronic Stress
Lower brain glucose levels found in people with obesity, type 2 diabetes
Glucose levels are reduced in the brains of individuals with obesity and type 2 diabetes compared to lean individuals, according to a new Yale study. The finding might explain disordered eating behavior — and even a higher risk of Alzheimer’s disease — among obese and diabetic individuals, the researchers said.
Yale launches five-year study of origins of autism
Yale researchers will study the development of functional brain connectivity during late pregnancy to early adolescence thanks to a five-year, $12.4 million grant from Autism Centers of Excellence Program, part of efforts by the National Institutes of Health to understand the origins of autism spectrum disorders (ASD).
How neurofeedback helps patients tamp down their fears
Tiny parts of the brain, School of Medicine researchers are discovering, can have a huge impact on our lives. Michelle Hampson, Ph.D., and Judson A. Brewer, M.D., Ph.D., are leading teams that use real-time fMRI and what’s known as neurofeedback to try to teach people how to control brain activity and combat such problems as anxiety, addiction, Tourette syndrome, and post-traumatic stress disorder (PTSD), as well as more mundane self-imposed roadblocks to success.
Levels of key brain chemicals predict children’s reading ability
Reading-impaired young children have higher levels of the metabolites glutamate and choline in their brains, and these higher levels continue to be indicative of difficulties in developing typical reading and language skills, a Yale study has found. The study appears in the Journal of Neuroscience.
Addicts’ cravings have different roots in men and women
A new brain imaging study by Yale School of Medicine researchers suggests stress robustly activates areas of the brain associated with craving in cocaine-dependent women, while drug cues activate similar brain regions in cocaine-dependent men. The study, expected to be published online Jan. 31 in the American Journal of Psychiatry, suggests men and women with cocaine dependence might benefit more from different treatment options.
Pietro De Camilli Selected for 2021 E.B. Wilson Medal
Pietro De Camilli, professor of Neuroscience and Cell Biology at Yale University and a Howard Hughes Medical Institute investigator, has been chosen by ASCB to receive the 2021 E.B. Wilson Medal. De Camilli is also the director of the Kavli Institute of Neuroscience at the Yale University School of Medicine.Source: American Society for Cell Biology
Powers Receives the Carol and Gene Ludwig Award for Early Career Research
Albert Powers, MD, PhD, Assistant Professor of Psychiatry and Psychology, and Medical Director and Associate Director of the Yale PRIME Psychosis Risk Research Clinic, has received the Carol and Gene Ludwig Award for Early Career Research from the Carol and Gene Ludwig Family Foundation.
Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder
"This study addresses several important areas that are underrepresented in the literature. Notably, this study focused on Spanish-speaking-only Latinx individuals who are underrepresented in treatment research on both binge-eating disorder and on obesity. Understanding the effects of existing treatments in culturally diverse samples is imperative so that treatments can be refined and effectively disseminated more broadly. Additionally, evaluating specific behavioral changes that are components of complex interventions may contribute to a better understanding of ways to enhance treatment outcomes and to guide more targeted dismantling studies," said Carlos Grilo, PhD, Professor of Psychiatry and of Psychology and Director of the Program for Obesity Weight and Eating Research (POWER).Source: Obesity
Psychiatric Sequelae of Stroke Affecting the Non-dominant Cerebral Hemisphere
Stephanie Yarnell-Mac Grory, MD, PhD, Assistant Clinical Professor of Psychiatry, and Robert Blake Werner, Jr., MD, Assistant Professor of Psychiatry, are co-authors of the paper "Psychiatric Sequelae of Stroke Affecting the Non-dominant Cerebral Hemisphere" published in Journal of Neurological Sciences.Source: Journal of Neurological Sciences
Workforce Development in Public Psychiatry: Impact of the Yale Fellowship
Jeanne L. Steiner, DO, Professor of Psychiatry; Walter S. Mathis, MD, Assistant Professor of Psychiatry; Dale D. Sebastian, MD, Assistant Professor of Psychiatry; and Tobias D. Wasser, MD, Associate Professor of Psychiatry are co-authors of a paper in Academic Psychiatry that highlights the impact and growth of the Yale Fellowship in Public Psychiatry.Source: Academic Psychiatry