2010
Common Genes Contribute to Depressive Symptoms and Heart Rate Variability: The Twins Heart Study
Su S, Lampert R, Lee F, Bremner JD, Snieder H, Jones L, Murrah NV, Goldberg J, Vaccarino V. Common Genes Contribute to Depressive Symptoms and Heart Rate Variability: The Twins Heart Study. Twin Research And Human Genetics 2010, 13: 1-9. PMID: 20158303, PMCID: PMC2905576, DOI: 10.1375/twin.13.1.1.Peer-Reviewed Original ResearchConceptsHeart rate variabilityCoronary artery diseaseDepressive symptomsHRV indicesReduced heart rate variabilityRate variabilityElectrocardiographic Holter recordingsMeasurements of HRVBeck Depression Inventory-IICurrent depressive symptomsSignificant inverse correlationVietnam Era Twin RegistryFrequency domain variablesBivariate genetic modelingCommon neurobiological dysfunctionArtery diseaseAutonomic dysregulationHolter recordingsHeart StudyMiddle-aged male twinsHRV frequencySymptomsCommon genetic componentInventory-IIHigh frequency
2008
Depressive Symptoms and Heart Rate Variability: Evidence for a Shared Genetic Substrate in a Study of Twins
Vaccarino V, Lampert R, Bremner JD, Lee F, Su S, Maisano C, Murrah NV, Jones L, Jawed F, Afzal N, Ashraf A, Goldberg J. Depressive Symptoms and Heart Rate Variability: Evidence for a Shared Genetic Substrate in a Study of Twins. Psychosomatic Medicine 2008, 70: 628-636. PMID: 18606724, PMCID: PMC5884077, DOI: 10.1097/psy.0b013e31817bcc9e.Peer-Reviewed Original Research