Researchers develop a novel RNA-based therapy to target West Nile Virus
A Yale-led research team developed a new RNA therapy, delivered through the nose, to treat mice infected with West Nile Virus. The innovative approach reduced the virus in the brain, allowing the immune system to destroy the virus and develop long-term protection against West Nile Virus disease, the researchers said.
Unpredictability the key to “rewiring” our fight against infection: In conversation with Professor John MacMicking
John MacMicking of the Systems Biology Institute talks about his work to integrate abstract and experimental science in an effort to “rewire” the host immune response to infection. Dr. MacMicking is an Investigator of the Howard Hughes Medical Institute (HHMI) and tenured Associate Professor of Microbial Pathogenesis and of Immunobiology at the School of Medicine.
Celebrating 18 Years of Microbial Pathogenesis at Yale on the Occasion of Jorge Galán’s 60th Birthday
The Department of Microbial Pathogenesis is pleased to invite our colleagues and friends to attend a symposium on Oct. 14 commemorating 18 years of Microbial Pathogenesis at Yale University, being held on the occasion of Dr. Jorge Galán’s 60th birthday. Following the symposium there will be a reception open to all participants at the Peabody Museum.
Five young Yale scientists recognized for excellence
Five Yale faculty members are among the 84 young researchers designated as Faculty Scholars under a new program to promote early career scientists, launched by the Howard Hughes Medical Institute, the Simons Foundation, and the Bill and Melinda Gates Foundation.
Yale Receives Funding to Study Myasthenia Gravis
The National Institutes of Health through the Rare Diseases Clinical Research Consortia has awarded a research team from Yale University, George Washington University, and Duke University $7.8 million to establish a rare disease network for myasthenia gravis.
Yale Researchers Identify Rare Inherited Immune Disease
When a 9-year-old girl with anemia, breathing problems, and recurrent infections sought help for her mysterious ailments, Yale researchers and their collaborators at the National Institutes of Health sequenced her genes to pinpoint a cause. What they discovered was not only a new disease but unexpected new roles for a gene that affects the immune system.
Blavatnik Gift Will Fund Research into the Biology of Survival
Medzhitov and his research team are working to uncover the mechanisms underlying survival strategies—also known as maintenance programs—an endeavor that will both advance fundamental biology and provide new therapeutic targets to prevent and treat disease.
Genome screen uncovers new targets for cancer immunotherapy
A new genome-wide screen of 20,000 human genes in T cells have turned up several new candidates to unleash the immune system’s ability to attack a variety of tumor types, Yale Cancer Center researchers report Aug. 22 in the journal Cell.
Mechanical forces impact immune response in the lungs
Mechanical forces impact immune response in the lungs By Ziba Kashef August 21, 2019 Share this with Facebook Share this with Twitter Share this with LinkedIn Share this with Email Print this 3d rendered medically accurate illustration of a mans lung (© stock.adobe.com) When the body is fending off an infection, there are changes in temperature, pH balance, and metabolism. Yale researchers wondered if yet other factors might come into play, and in a recent study, confirmed that mechanical forces also influence the immune response.
Rothlin Is Appointed McConnell Duberg Professor
Carla Vanina Rothlin, PhD, newly named as Dorys McConnell Duberg Professor of Immunobiology, studies the mechanisms that regulate the magnitude and resolution of the immune response. Rothlin is also a professor of pharmacology, a member of the Yale Cancer Center, and a Howard Hughes Faculty Scholar.
Herold Is Designated C.N.H. Long Professor
Kevan Herold, MD, newly named as C.N.H. Long Professor of Immunobiology and of Medicine, conducts research on the basis for autoimmune diseases and develops new therapies based on these studies. His focus has largely been in the field of autoimmune Type 1 diabetes.
Study Explores Role of Metabolism in Immune Cell Behavior
What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say Yale researchers.