Professor of Chemistry and of Microbial Pathogenesis
Bacteria; Chemistry; Host-Pathogen Interactions.Crawford Lab
Bacteria
Bacteria are unicellular, prokaryotic organisms that live all around and within us, usually without incident. However, a number of important bacterial pathogens can cause opportunistic infections that are severe or life threatening. The bacteriologists within the Department have made numerous contributions to our understanding of how bacteria cause disease.
Faculty and Labs
Associate Professor Adjunct; Director, Center for Pulmonary Infection Research and Treatment (CPIRT)
Respiratory Tract Infections; Pulmonary Disease, Chronic Obstructive.Dela Cruz LabWaldemar Von Zedtwitz Professor of Medicine (Infectious Diseases) and Professor of Epidemiology (Microbial Diseases) and of Microbial Pathogenesis; Affiliated Faculty, Yale Institute for Global Health; Section Chief, Infectious Diseases, Internal Medicine
Tick-borne transmission of Borrelia burgdorferi (the causative agent of Lyme disease) and Anaplasma phagocytophilum(which causes human granulocytic anaplasmosis); Mosquito transmission of flaviruses and Plasmodium; Innate immune responses and vaccine design.Lucille P. Markey Professor of Microbial Pathogenesis and Professor of Cell Biology
Bacterial type III secretion systems; virulence determinants of food-borne pathogens Salmonellatyphimurium, S. typhi, and Campylobacter jejuni Galán LabC.N.H. Long Professor of Microbial Pathogenesis and Director of Microbial Sciences Institute; Chair, Microbial Pathogenesis
Microbial communities within the gut; the relationship between microbiota composition and function; functional genome-wide analysis. Goodman LabWaldemar Von Zedtwitz Professor of Microbial Pathogenesis
Bacterial two-component signal transduction in Salmonella enterica (which causes gastroenteritis and typhoid fever), Yersinia pestis (which causes bubonic plague), and Escherichia coli (which is a commensal bacteria of the gut); genetic networks and differential gene control; riboswitches. Groisman LabAssociate Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis; Director ID/Rheum Research Conference, Internal Medicine
Chlamydia trachomatis; Trachoma; Infectious Disease Medicine.Gustavus and Louise Pfeiffer Research Foundation M.D.-Ph.D. Program Director and Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis; Professor, Microbial Pathogenesis; Director, MD-PhD Program, Yale University
Virulence factors of Pseudomonas aeruginosa; bacterial biofilm formation.Professor of Microbial Pathogenesis and of Immunobiology; Member, Yale Systems Biology Institute; Investigator, Howard Hughes Medical Institute
Cell-autonomous immunity to microbial pathogens; interferon-induced host defense; structural analysis of antimicrobial nanomachines.Associate Professor Term
Bacteria; Cell Biology; Imaging, Three-Dimensional; Single-Cell Analysis. Rego LabWaldemar Von Zedtwitz Professor of Microbial Pathogenesis and of Immunobiology and Director of Biological and Biomedical Sciences (BBS); Vice-Chair, Department of Microbial Pathogenesis
Remodeling of the host cellular secretory pathway by Legionella pneumophila (Legionnaire’s disease) and Coxiella burnetii (Q fever) effector proteins; bacterial evasion of innate immune responses.