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Yale School of Medicine: Reaching Our Vision

September 29, 2022

Yale School of Medicine: Reaching Our Vision

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  • 00:00Doctor Brown served for 9 years
  • 00:01as the chair of the Department of
  • 00:03Medicine at Vanderbilt Development of
  • 00:05infrastructure to promote the career
  • 00:07success of physician scientists.
  • 00:09She founded the Vanderbilt Master of Science
  • 00:11and Clinical Investigation program in 2000,
  • 00:13served as associate Dean for clinical
  • 00:15and Translational Scientist development
  • 00:17at Vanderbilt from 2006 to 2010,
  • 00:19and is the director of the Division of
  • 00:22Clinical Pharmacology from 2009 to 2010.
  • 00:24Doctor Brown's NIH funded research
  • 00:26focuses on cardiovascular pharmacology
  • 00:28and vascular biology and humans.
  • 00:31She's particularly interested in
  • 00:32understanding the mechanisms of
  • 00:34antihypertensive and antidiabetic
  • 00:35drugs that are peptidase inhibitors,
  • 00:37including the angiotensin converting
  • 00:39enzyme inhibitors,
  • 00:40dipeptidyl peptidase 4 inhibitors,
  • 00:43and neprilysin inhibitors.
  • 00:45Our group has a loose stated not only
  • 00:46how these drugs decrease inflammation,
  • 00:48enhance fibrinolysis,
  • 00:49the breakdown of blood clots,
  • 00:51and improve glucose homeostasis,
  • 00:52but also how they interact with one
  • 00:54another and sometimes cause side effects.
  • 00:56This understanding leads to
  • 00:58optimizing outcomes in patients
  • 01:00with hypertension and diabetes.
  • 01:01Doctor Brown received her AB in molecular
  • 01:04biophysics and biochemistry from Yale
  • 01:05and her MD from Harvard Medical School.
  • 01:07She completed her clinical training
  • 01:09at a fellowship in clinical
  • 01:10pharmacology at Vanderbilt University.
  • 01:12Doctor Brown is a fellow of the American
  • 01:14Association for the Advancement of
  • 01:16Science and a member of the American
  • 01:17Society of Clinical Investigation,
  • 01:19the Association of American Physicians,
  • 01:21the National Academy of Medicine,
  • 01:23and the American Academy of
  • 01:24Arts and Sciences.
  • 01:25She is a master of the American
  • 01:27College of Physicians and a Fellow
  • 01:28of the Royal College of Physicians.
  • 01:29She has served on the
  • 01:31National advisory Research.
  • 01:31Resources Council and the National Heart,
  • 01:33lung and Blood Advisory Council of
  • 01:35the National Institutes of Health.
  • 01:36Doctor Brown currently serves on the
  • 01:38Visiting committee for Harvard Medical
  • 01:40School and the External Advisory
  • 01:41Board for the Harvard MIT Health
  • 01:43Sciences and Technology program.
  • 01:44Finally,
  • 01:45she's a member of the Scientific Advisory
  • 01:47Board for Alnylam Pharmaceuticals.
  • 01:50Thank you very much, Dean Brown,
  • 01:51and cheers to take away.
  • 01:53Thank you. Ariel and I will
  • 01:54share some slides here.
  • 02:03Can you all see those? Great.
  • 02:05So thank you for the invitation to
  • 02:07speak and and for those of you who
  • 02:10have seen the state of the school,
  • 02:11there will be some repetition,
  • 02:13but some some updates as well.
  • 02:16And the title of this is really
  • 02:18to think with you about how we
  • 02:21become all that we can, we can be.
  • 02:24And I will start by reminding
  • 02:28of our mission statement because
  • 02:30everything that I'm going to talk
  • 02:33to about today really derives.
  • 02:35From this Commission first,
  • 02:37that we educate and nurture creative
  • 02:40leaders in medicine and science by
  • 02:42promoting curiosity and critical
  • 02:44inquiry in an inclusive environment
  • 02:46which is enriched by diversity.
  • 02:48Also that we advanced discovery
  • 02:50and innovation fostered by
  • 02:51partnerships across the university
  • 02:53and our local community as well as
  • 02:55other institutions in the world.
  • 02:57And that we care for
  • 02:59patients with compassion,
  • 03:00but also commit to improving
  • 03:02the health of all people.
  • 03:03So as I think about the strategic planning.
  • 03:06That we've done over the last 2 1/2 years,
  • 03:09often in specific areas like education
  • 03:12or research or clinical enterprise.
  • 03:14There are several cross cutting
  • 03:16themes that I'd like to highlight
  • 03:18as we talked today and the first
  • 03:21is this creation of an environment
  • 03:23of inclusive excellence where every
  • 03:25member of our Community can thrive.
  • 03:27And to which we can continue to
  • 03:29recruit the best talent in the world.
  • 03:31We have amazing people at Yale,
  • 03:34and much of our investments over
  • 03:37the last few years is creating a
  • 03:40culture that enables people to
  • 03:42reach their full potential.
  • 03:44And I'll talk a lot about how we
  • 03:46are working on climate and how we're
  • 03:48working on career development.
  • 03:51A second cross cutting theme is the
  • 03:54notion of breaking down silos across
  • 03:56departments between the school and
  • 03:59our Yale New Haven Health system,
  • 04:01between the school and our other
  • 04:04collaborators and the institution
  • 04:06in the university.
  • 04:08And by doing this,
  • 04:09how we promote interdisciplinary research
  • 04:11to increase the impact of our science.
  • 04:14Our science has always been excellent.
  • 04:16But we can do higher impact
  • 04:19science through doing this.
  • 04:20Related to that is building resources
  • 04:24that serve biomedical discovery.
  • 04:26So as a a School of Medicine,
  • 04:28we are always thinking about
  • 04:31recruiting talent,
  • 04:32but we also need to build the cross
  • 04:35cutting resources that enable discoveries.
  • 04:36And so we'll talk about some of
  • 04:39our investments in those areas.
  • 04:41And then lastly,
  • 04:43you know our clinical mission
  • 04:45is extremely important.
  • 04:47We provide care often for underserved
  • 04:49in our community and we do that
  • 04:52in our partnership with the owner
  • 04:54even health system and we are
  • 04:56working a great deal on,
  • 04:57on aligning to become the premier
  • 05:00academic health system that we can be.
  • 05:03So we'll talk a little bit about leadership.
  • 05:04As I say we we are in the business
  • 05:07of recruiting talent and that
  • 05:09means both excellence in research,
  • 05:11education and clinical work,
  • 05:12but also people who share the values
  • 05:15of our school and who are leaders.
  • 05:18This highlights some recent
  • 05:19recruitments over the last few years,
  • 05:22most recently for example Eric Weiner and
  • 05:25joined us in February as the director
  • 05:27of our Cancer Center investments
  • 05:29in some of our research centers.
  • 05:32Leadership Anton Bennett in
  • 05:34molecular and systems metabolism,
  • 05:37Carlos Fernandez Hernando in
  • 05:38vascular biology and Therapeutics,
  • 05:40and Akiko Osaki leading a new
  • 05:43Center for infection and immunity.
  • 05:45We've also recruited leaders both
  • 05:48internally and externally into deputy
  • 05:52Deans roles and I would highlight
  • 05:54these three Bob Rorbach who is leading
  • 05:57our efforts in professionalism and
  • 05:59leadership development and really
  • 06:01establishing an infrastructure where
  • 06:03we can recognize when a faculty
  • 06:06member or a staff member or even
  • 06:08a student are struggling with
  • 06:10issues around professionalism.
  • 06:12We can recognize that early
  • 06:14make early interventions.
  • 06:15To really change our culture overall.
  • 06:21Dante's joined us a little over a
  • 06:24year ago from UT Southwestern and is
  • 06:27bringing new processes and analytics
  • 06:30that enable efficiencies and less,
  • 06:33I would say.
  • 06:36Bureaucracy for our faculty and then
  • 06:39most recently, doctor Peggy McGovern
  • 06:41has joined us as CEO of Yale Medicine
  • 06:44and is our Deputy for Clinical Affairs.
  • 06:47And we'll talk about what that has
  • 06:49enabled in terms of alignment.
  • 06:51In education, of course.
  • 06:53John Francis joined us about
  • 06:55November a year ago as our associate
  • 06:57Dean for Student Affairs.
  • 06:58Veronica Chang assumed the position
  • 07:00of assistant Dean for admissions,
  • 07:02and Marietta Vasquez became associate
  • 07:05Dean for medical student diversity.
  • 07:07There are other things going on in the
  • 07:09campus outside the School of Medicine
  • 07:11that impact on the School of Medicine.
  • 07:13And one is the creation of a freestanding
  • 07:17school of engineering and applied
  • 07:19science led by Dean Jeff Brock,
  • 07:21who has been a tremendous partner,
  • 07:22and I'll talk about that as I talk
  • 07:25about biomedical informatics.
  • 07:26And the other is the full separation
  • 07:29of the Yale School of Public Health,
  • 07:31anticipated after the recruitment
  • 07:33of the new Dean to become a self
  • 07:36supporting and independent.
  • 07:38Right now the School of Public
  • 07:40Health is something in an in between
  • 07:42situation where it is has a Dean
  • 07:44appointed by the President and
  • 07:46sets many of its own policies.
  • 07:48But financially is acts as a department
  • 07:51in the School of Medicine and Melinda
  • 07:54Irwin has recently chaired a search
  • 07:56and and there are finalists for that
  • 08:00permanent Dean's position and our
  • 08:02interim Dean is Melinda Pettigrew.
  • 08:05So one of the ways that we create
  • 08:08an environment that is inclusive is
  • 08:11by celebrating the accomplishments
  • 08:12of our faculty.
  • 08:13And we often do this with traditional
  • 08:16academic accomplishments as shown
  • 08:17here election into the American
  • 08:19Society for Clinical Investigation,
  • 08:21National Academy, etcetera.
  • 08:23Or large awards like the awards
  • 08:27garnered by Doctor de Camilli and
  • 08:30Doctor Ruttle and Doctor Cruz last year.
  • 08:34But it but.
  • 08:35Also in the recognition by our peers
  • 08:37and so I would highlight our faculty
  • 08:40who were honored with distinguished
  • 08:42Political career awards and Mike
  • 08:45Katie who received the David Leffell
  • 08:48Prize for Clinical Excellence.
  • 08:50We are making an effort to be more
  • 08:54intentional about recognizing our staff
  • 08:57who enable that mission that we started with.
  • 09:01So we had some who received the
  • 09:03Linda Lorimer award last year in
  • 09:05the Department of Psychiatry and
  • 09:07we've had three members of our staff
  • 09:10recently complete the Emerge program,
  • 09:12which is a leadership development program,
  • 09:15again emphasizing career development.
  • 09:18And we further communicate about
  • 09:21the accomplishments of our faculty,
  • 09:23staff and students through our
  • 09:25weekly news and recognition.
  • 09:27This goes out to our school,
  • 09:28but we also now send it
  • 09:31to our peer institutions,
  • 09:32the Deans,
  • 09:33and to our alumni as a way of of
  • 09:36really highlighting everything
  • 09:37that is going on here,
  • 09:39because I think we've often been
  • 09:42a little bit shy to do that.
  • 09:44We actually track our communications
  • 09:46to to know are we getting the word
  • 09:49out about the impact of our faculty.
  • 09:52And so for example,
  • 09:55if you Googled Ms and inflammation,
  • 09:58we had the top hit based on our one of
  • 10:01the sometime second hit.
  • 10:03Our stories that related to COVID
  • 10:05have brought many people to the to
  • 10:07our websites who are patients who
  • 10:09can benefit from our healthcare.
  • 10:11And so these are some examples of efforts.
  • 10:14Not area. Let me turn it now to
  • 10:18education and this will look familiar.
  • 10:21It's our incoming class,
  • 10:23which is just outstanding.
  • 10:25And we continue to recruit a diverse
  • 10:29group of students with about 24%
  • 10:31this year from groups traditionally
  • 10:34underrepresented in medicine and
  • 10:36slightly more women than men and with
  • 10:38many of our students having been born
  • 10:41outside the United States and roughly
  • 10:43about 14% of our students being first
  • 10:45generation first in their family.
  • 10:47Complete a college education and as
  • 10:49you can see outstanding stores scores
  • 10:52and coming from the top institutions.
  • 10:55I'm particularly pleased that our
  • 10:57students also when they leave here,
  • 11:00if they leave here,
  • 11:01go to the top institutions as well.
  • 11:04And this is the example of where
  • 11:08our students went after this year.
  • 11:10In the education room,
  • 11:12we are leading in in some particular
  • 11:14areas and and one is in the use of
  • 11:17technology received again and annotation
  • 11:20as an Apple distinguished school for
  • 11:22the the period of 2021 and 2024 and
  • 11:25you could see Mike Schwartz there.
  • 11:27He's often led these efforts.
  • 11:30Umm.
  • 11:31Since Jessica Illuzzi came
  • 11:33in January of 2021,
  • 11:36we've had she's engaged in taking a
  • 11:40look at our medical education programs
  • 11:43and has recently led strategic planning
  • 11:46that identified 3 cross cutting themes.
  • 11:49The first is the.
  • 11:52Engagement of our students in attaining
  • 11:55competency and and by that we mean,
  • 11:58you know,
  • 11:59our medical students benefit from the
  • 12:03Yale system in having a great deal of.
  • 12:07Choice and the ability to tailor
  • 12:11your education.
  • 12:12And.
  • 12:15How you think about whether you're
  • 12:17achieving your goals is something
  • 12:19that we'd like to work on.
  • 12:20We don't have grades.
  • 12:22We believe that you are adults
  • 12:24and you need to be able to.
  • 12:28Do self evaluation.
  • 12:29It's part of lifelong learning
  • 12:31and so developing systems,
  • 12:33including coaching systems
  • 12:34that allow you to do that is
  • 12:37one of the strategic goals.
  • 12:40Included in that, as I mentioned,
  • 12:41our coaches and so a little more hands-on.
  • 12:48Ability to to get input beyond what
  • 12:51you have now with the advisor program.
  • 12:54The second domain is enhancing faculty
  • 12:56engagement in the educational mission.
  • 12:58And Jessica and others have done a lot
  • 13:00of work in the last year making sure
  • 13:02that we're adequately rewarding our
  • 13:04faculty for their educational efforts,
  • 13:06including changing how we fund effort
  • 13:10for education and most recently,
  • 13:13changing our definitions of our promotion
  • 13:16tracks in the faculty handbook that still
  • 13:19has yet to be approved by the corporation,
  • 13:23but to acknowledge.
  • 13:24Work that is innovative in
  • 13:27leading educational programs,
  • 13:29even when that work does not
  • 13:32result in a scholarly production,
  • 13:36although I think we can do much
  • 13:38better again in getting the word out
  • 13:40about the innovation going on here.
  • 13:42And then building an environment that
  • 13:45is more inclusive and by doing things
  • 13:49like creating colleges for the students.
  • 13:51I know many of you have been engaged
  • 13:54in this work and others of you
  • 13:56will be engaged in the next phase.
  • 13:58We are coming up just a year away on a
  • 14:01visit from LCME and I'm very grateful to
  • 14:05our students who have completed a self study.
  • 14:08We've been working on our
  • 14:10DCI and now of course the.
  • 14:12The Self Study group is reviewing
  • 14:14all those materials.
  • 14:16This is a lot of work.
  • 14:18I hope that it is a labor of love
  • 14:20for those of you who are involved it.
  • 14:23It is,
  • 14:24you know,
  • 14:25obviously important to be accredited,
  • 14:27but it's more important in that it gives
  • 14:30us time to reflect and think about
  • 14:33where we can continue to innovate and
  • 14:35and provide the best medical education.
  • 14:38Turning to culture and climate,
  • 14:41one of the hallmarks of our
  • 14:45efforts to develop faculty,
  • 14:47but also to develop in particular those
  • 14:49who have been underrepresented in medicine,
  • 14:52is to make sure that we are
  • 14:55meeting with faculty early enough,
  • 14:57identifying their needs,
  • 14:59helping reduce barriers.
  • 15:01One of the things that I've heard
  • 15:03most often when I've had listening
  • 15:05meetings with faculty is they.
  • 15:07They feel like they don't always
  • 15:10get as much input as they need.
  • 15:13Many of our departments have annual reviews,
  • 15:16but when you look at whether they're
  • 15:19really happening and whether they're
  • 15:21as useful as they need to be,
  • 15:22in some cases they have not.
  • 15:24So we've worked to standardize this.
  • 15:26The group that's on the right
  • 15:29there has been involved in an
  • 15:31iterative process with input from.
  • 15:33Departments that that piloted a
  • 15:36form that can be used as part of
  • 15:39the annual meeting and this we've
  • 15:42had very positive feedback and
  • 15:44that people really felt that they
  • 15:46received input that was helpful
  • 15:47in their career development.
  • 15:49So we are going live with this as
  • 15:52of this month for this this academic
  • 15:54year and asking our departments to
  • 15:57reach some goals in completing this.
  • 16:00The formal diversity and inclusion
  • 16:03strategic plans are online at the office
  • 16:08of EI and they include many features,
  • 16:11again focused on active retention
  • 16:13of our faculty as well as recruiting
  • 16:17retention of our students into
  • 16:19trainees and our trainees into faculty.
  • 16:22One of the things that we've wanted
  • 16:24to do is have some discipline around
  • 16:26this work so that everyone isn't
  • 16:27reinventing the wheel and part of that.
  • 16:29Is sharing best practices,
  • 16:31and so we've gathered a committee of.
  • 16:36University vice chairs and champions.
  • 16:38It's led by Darren Matamore and the
  • 16:41goals there are to collect data that we
  • 16:44can use to make continual improvement.
  • 16:47I present data at our state of the school
  • 16:49such as this that I'm showing here.
  • 16:52This just shows the growth in
  • 16:54representation of those groups
  • 16:55traditionally underrepresented in medicine
  • 16:57in the school over year over year.
  • 17:00It was at 5 year intervals in
  • 17:02the first few bars,
  • 17:03but now year over year showing that we
  • 17:05are seeing progress in recruiting and in
  • 17:09promoting to the associate professor.
  • 17:11Now we have to work on promoting
  • 17:13to the professor level and similar
  • 17:16data for our women. In medicine.
  • 17:18And starting to show new data that
  • 17:22to to look at other things other
  • 17:24than just numbers of faculty,
  • 17:26but including things like among our faculty,
  • 17:30among our professors,
  • 17:32what proportion of our professorships
  • 17:34are endowed shares are held by
  • 17:37women or those underrepresented
  • 17:38in minority and medicine.
  • 17:40And you can see that for the
  • 17:43underrepresented medicine,
  • 17:43it's actually a higher portion than
  • 17:46the than the denominator about the
  • 17:48same for about equivalent to the
  • 17:51number of women who are professors.
  • 17:52So we're consciously looking
  • 17:54at those sorts of things.
  • 17:56We are also doing a lot of work,
  • 17:59or as I said around.
  • 18:01Our environment and how do we
  • 18:04respond if someone is noted to have
  • 18:08struggling with with behavioral
  • 18:10issues or those kinds of things.
  • 18:13Those of you haven't go to the LAPD
  • 18:17website and and read the processes
  • 18:20that we use were very dedicated
  • 18:22to making it feasible for somebody
  • 18:24to come forward without fear of
  • 18:27retaliation and to follow up and to
  • 18:29try to get follow up to those who have.
  • 18:32Move forward,
  • 18:32we're also tracking what kinds of
  • 18:35things we're seeing and these are data
  • 18:37from Bob Rohrbaugh over the last year.
  • 18:40And you can see the pie chart there
  • 18:42that 77% of the concerns that are
  • 18:45expressed are around professionalism.
  • 18:47And I'll go into more detail,
  • 18:48about 13% are around what I would
  • 18:51call climate within a within a unit.
  • 18:54About 3% are related to sexual
  • 18:56harassment or Title 9,
  • 18:58I should say Title 9 issues
  • 19:00and those sorts of things, so.
  • 19:02Looking drilling down in the
  • 19:04professionalism categories disruptive
  • 19:06or inappropriate behavior is by
  • 19:08far the that the farthest the most
  • 19:11prevalent and this is sometimes you
  • 19:13know things in the category of anger
  • 19:16management those sorts of things and.
  • 19:20Recognizing this early and and finding
  • 19:23often that there are underlying issues
  • 19:26either in somebody's personal life
  • 19:29or frustrations that are ongoing
  • 19:32in the environment.
  • 19:34So correcting those things,
  • 19:36but then also giving faculty
  • 19:38coaching to help them improve and
  • 19:41change before something more serious
  • 19:44happens. Some of these happen in the
  • 19:46student and training environment.
  • 19:48Some of them are related
  • 19:49to compliance issues. Few.
  • 19:51Related to harassment or bullying,
  • 19:53so you can see the categorization.
  • 19:55I'll point out that there are some
  • 19:57that are sexual misconduct and
  • 19:59harassment that we're seeing but that
  • 20:01are not in the Title 9 category.
  • 20:03In other words, where the Title 9
  • 20:05Office has said this is not has
  • 20:07not reached a level for our office.
  • 20:09So we will make efforts to start to to
  • 20:13get this information out a little bit more.
  • 20:18Again, creating an inclusive environment,
  • 20:20paying attention to the needs of our faculty.
  • 20:22A common need for our faculty
  • 20:25is support for child rearing,
  • 20:27and in the past year we have increased
  • 20:30extended our time for a paid leave for
  • 20:33child rearing from 8 weeks to 12 weeks,
  • 20:36in part leveraging a new Connecticut law.
  • 20:40This is not easy because it creates
  • 20:43other stresses in the system,
  • 20:45for example, making sure that.
  • 20:47We can provide adequate clinical
  • 20:51coverage when we have small units that
  • 20:53have just a small number of faculty.
  • 20:55So we are recently convening a committee
  • 20:58of members of FAC and administrators to
  • 21:01think through how do we have consistency,
  • 21:05consistent policies around such
  • 21:08issues across departments.
  • 21:10And then we have for many years now since
  • 21:142014 tracked gaps in salary between.
  • 21:18Between our male and female faculty
  • 21:20members and where we see this is in our
  • 21:24clinical departments as you can see here,
  • 21:27perhaps the closing gap,
  • 21:28but we also changed our methodology
  • 21:30in the last year.
  • 21:31And you can see the variance variables
  • 21:33that go into this multivariate regression
  • 21:35analysis and see those things that
  • 21:38have the biggest impact on salary by
  • 21:40far and away it's your subspecialty.
  • 21:42So what is the double AMC median
  • 21:45salary for someone,
  • 21:47but there are other things that.
  • 21:49Obviously it you know how much
  • 21:51political work you do have an impact
  • 21:53and so these things are all controlled
  • 21:55for and yet we still have a gap.
  • 21:57What we do with these data are look
  • 21:59department by department and what
  • 22:01we've found is that when we do that
  • 22:04we are able to bring a department that
  • 22:07may have gotten out of line back into
  • 22:10line back to zero and and we in the
  • 22:13process often identify systemic issues
  • 22:16that we can address across departments.
  • 22:19And this is just the the example of
  • 22:22how we look at this by department
  • 22:25and you can see this department was
  • 22:27one that we focused on this year.
  • 22:30I would point out that one of these
  • 22:33departments that is at around zero
  • 22:34was one that had a very large gap
  • 22:36in salary just a few years ago.
  • 22:40Let me turn now to our research mission.
  • 22:43You know one of the questions is how do
  • 22:45you track your success in research and
  • 22:48ultimately you want to track impact.
  • 22:50It's the number of drugs that you bring to,
  • 22:54to patients or the number
  • 22:57of deaths that you prevent.
  • 22:59Those are very long-term things to track
  • 23:01and you know we are now have drugs
  • 23:03coming to market that are based on basic
  • 23:06science research that was done 30 years ago.
  • 23:09So we often track leading indicators
  • 23:11like NIH funding shown here
  • 23:13and you can see we're in that,
  • 23:15you know, tightly.
  • 23:19Clustered group in the four to 8 range
  • 23:22and we bounce around between there.
  • 23:24I would say we tend to be very high
  • 23:27in the number of single investigator
  • 23:30grants and that's a hard way to.
  • 23:33Have large, have as big an NIH budget as
  • 23:37we have and so we've been emphasizing.
  • 23:40Again, interdisciplinary large grants
  • 23:42and then this just shows the data
  • 23:44by department and I think you know
  • 23:46you can see that about half of our
  • 23:49departments are in the top ten in
  • 23:51NIH funding and you know many are
  • 23:53year over year in the top one or two
  • 23:55such as psychiatry and medicine.
  • 23:57Our faculty of course also do research
  • 24:00at the VA and it's a it's not an
  • 24:04insignificant amount and the VA
  • 24:06research program is a really wonderful.
  • 24:10Resource,
  • 24:10particularly for new investigators to
  • 24:13to maximize their chance of getting funded.
  • 24:17There are pressures on our research program
  • 24:20beyond just getting funding support.
  • 24:22One of those has been a decline in
  • 24:25the number of graduate students and
  • 24:28and postdoctoral fellows who of
  • 24:30course are the future of discovery.
  • 24:32And there are several factors
  • 24:34that have come to bear.
  • 24:35One is the influence of recent
  • 24:41governmental policies around certain visa
  • 24:44holders and particularly from China.
  • 24:47The other is that we had,
  • 24:49we had a number of training grants
  • 24:52going through an NIH institute that is
  • 24:55decreasing the number of training grants.
  • 24:57So as an interim solution,
  • 24:59the School of Medicine along with
  • 25:01the Graduate School is funding slots
  • 25:03to maintain our ability to train
  • 25:06graduate students and postdoctoral
  • 25:08fellows while we come up with
  • 25:11other solutions to fund slots,
  • 25:13such as through endowment
  • 25:15or through collaborations.
  • 25:17With industry and those sorts of things.
  • 25:21We are working to increase the diversity
  • 25:24of our postdoctoral fellows as well.
  • 25:26And one of the things that we
  • 25:29appreciate is that often the best
  • 25:31way to grow talent is to invest
  • 25:33early and then retain that talent.
  • 25:36And so you,
  • 25:37fat Levy and Kristen Brennan are
  • 25:39leading a new program called
  • 25:41the Science Fellows Program,
  • 25:42which creates the ability to recruit
  • 25:46those superb postdoctoral fellows
  • 25:48and groom them for transition to
  • 25:51independence as faculty members.
  • 25:53This is envisioned to be cluster hires,
  • 25:55so that you're bringing in two or
  • 25:58three or four fellows at the same
  • 26:00time who are working in related areas.
  • 26:03We are also spending a lot of effort
  • 26:06on enabling our physician scientists.
  • 26:09This effort has been led by Keith Tote,
  • 26:12but also Nee Addy and Nick Click
  • 26:16Light who have created huge resources,
  • 26:19both salary support for people
  • 26:22beginning their careers,
  • 26:24mechanisms to make sure that mentorship
  • 26:26is working,
  • 26:26access to grant writing resources,
  • 26:29and the creation of the Janeway Society,
  • 26:30which brings together all of our
  • 26:33junior faculty.
  • 26:34To talk about how one starts a research
  • 26:38program. What are the barriers?
  • 26:39What? How?
  • 26:40How does one navigate those barriers?
  • 26:43We've created a successful grant
  • 26:45library so that those who are
  • 26:47submitting grants can can learn
  • 26:49from others who have
  • 26:51submitted successful grants.
  • 26:52And this is just the types of grants
  • 26:54that are included in that library.
  • 26:56And it it could not happen without
  • 26:58the generosity of our faculty who
  • 27:00are willing to share their grants,
  • 27:02including those that were not initially
  • 27:04funded and then got funded so we
  • 27:07can see how they responded to it,
  • 27:09to the comments from reviewers.
  • 27:13They have also developed mock study
  • 27:16sections and again the generosity
  • 27:18of many faculty who who participate
  • 27:20in those and review grants together.
  • 27:22And that ensures that when someone
  • 27:25then finally submits the grant to
  • 27:27the National Institutes of Health,
  • 27:28it is the best possible grant
  • 27:30that could go out the door.
  • 27:31And that enables them to get be more
  • 27:35likely to be funded the first time
  • 27:38through and shorten that time to funding.
  • 27:40Linda Bockenstedt has led an an effort
  • 27:43to look at our research faculty.
  • 27:45This is a track that is fundamental
  • 27:47to many research programs.
  • 27:49These are our faculty who have
  • 27:52particular expertise in methods
  • 27:54but perhaps don't desire to have an
  • 27:57independent research program and
  • 27:58the stresses of writing grants.
  • 28:01And but the issue that we have with this
  • 28:03track is that it's used in different ways,
  • 28:05and there's often a disconnect
  • 28:07between the expectations of a faculty
  • 28:09member and the expectations of.
  • 28:11Their principal investigator.
  • 28:12So that committee has made
  • 28:14a number of recommendations.
  • 28:16One is to clarify those expectations,
  • 28:18expectations at the outset of the
  • 28:21standard offer letter to create
  • 28:23individual pathways within this track
  • 28:26to do a better job of mentoring
  • 28:28this group of faculty,
  • 28:29including using a form like the F
  • 28:32DAC that we've developed and so
  • 28:35that we're in the process of
  • 28:37implementing those sorts of things.
  • 28:39Again,
  • 28:39as a way to increase the types
  • 28:41of faculty we're developing,
  • 28:43we have had an effort in biomedical
  • 28:45data science.
  • 28:46There's a real shortage of people
  • 28:48who have expertise in this area.
  • 28:50The students who are interested in this,
  • 28:52I would encourage you to pursue
  • 28:54those interests.
  • 28:55But this is a program in collaboration
  • 28:57with Burner Ingelheim where we have
  • 28:59grown it actually more rapidly than
  • 29:02anticipated because it's been so
  • 29:04successful and each student has
  • 29:06reach fellow has.
  • 29:08Mentor within the university and
  • 29:10a mentor within Barringer Anaheim,
  • 29:12allowing them to cross fertilize.
  • 29:16We have also recently recruited
  • 29:18Lucilla Ana Machado,
  • 29:19a member of the National Academy
  • 29:21of Medicine to lead what will start
  • 29:23as a freestanding section of
  • 29:25biomedical informatics and data science,
  • 29:27but evolve into a new department.
  • 29:30And Lucilla has been on campus quite a bit,
  • 29:34will be here today and tomorrow
  • 29:37really working.
  • 29:38And how we build better support for
  • 29:41our faculty, our students,
  • 29:43in terms of biomedical informatics.
  • 29:45And I'm aware that our students are
  • 29:47frustrated about access to J DAT,
  • 29:49and this is something that we still
  • 29:52will be able to help with.
  • 29:54We are in in the realm of cross
  • 29:58cutting research.
  • 29:59We recently stood up a Yale Center
  • 30:01for Brain and Mind Health.
  • 30:03As you know, we have very
  • 30:05strong neuroscience here.
  • 30:06The Woosah Institute was created
  • 30:08to study human cognition.
  • 30:10Yale New Haven Health System
  • 30:13is building a new neuroscience
  • 30:15tower for clinical neuroscience.
  • 30:17And there was a real need to create.
  • 30:22Mechanisms to bring discovery
  • 30:24into trials for our patients
  • 30:26and to learn from our patients.
  • 30:28And so this group of five faculty
  • 30:32members representing neurosurgery,
  • 30:34the Child Study Center,
  • 30:36psychiatry and neurology.
  • 30:38Interviewed all of the stakeholders,
  • 30:40convened a retreat,
  • 30:42strategic retreat and conceived
  • 30:45of this center,
  • 30:47which will create resources and bring
  • 30:50people here to translate discovery
  • 30:53into our into the clinical realm.
  • 30:56We have some roadblocks in that area.
  • 30:58One is that our our contracting
  • 31:01and our time to initiation
  • 31:04of clinical trials is slow.
  • 31:07Just the goal is that this
  • 31:08would happen within 90 days.
  • 31:09You can see over this two year
  • 31:11period that the vast majority of
  • 31:13contracts and initiations took longer.
  • 31:15We have a group that's working on this.
  • 31:17We have some things that we need to
  • 31:20tweak within the School of Medicine
  • 31:22before we can really fix this.
  • 31:24We're investing in, as I said,
  • 31:27resources to enable everybody's research.
  • 31:30One is a biorepository,
  • 31:32where we're collecting samples
  • 31:34from patients and keeping them
  • 31:37stored appropriately,
  • 31:38processed and stored appropriately so
  • 31:40that investigators can access them.
  • 31:42Two of the higher technology
  • 31:45cores that we are just standing
  • 31:47up is first A-fib SEM core,
  • 31:50being led by Shanzu and song.
  • 31:53Saying who we were very fortunate
  • 31:56to recruit from Janelia Farm and
  • 31:58who have developed mechanisms
  • 32:01using fibs them to image cells down
  • 32:05to the to the for Micron level
  • 32:09incredible resolution leading them
  • 32:11to be able to publish for example
  • 32:14in a collaborative group the the
  • 32:16connectome of the dress Drosophila
  • 32:19brain so really impressive work
  • 32:21and similarly a new Murphy.
  • 32:24Multiplexed fish for transcriptome imaging,
  • 32:27led by money dekmar that's
  • 32:29available to all of our resources.
  • 32:34Ironically, at this point our research
  • 32:37enterprise is not constrained by money,
  • 32:39but by space. We have a space plan.
  • 32:44In in place, and I would say we have it.
  • 32:48It's been somewhat frustrating because
  • 32:51we are already behind schedule
  • 32:54largely due to labor shortages and
  • 32:56supply chain shortages post COVID.
  • 32:59We just had a walk through of 300,
  • 33:01George again this morning to think about
  • 33:04what we need to do to improve this building.
  • 33:07But you can see that after we
  • 33:10complete renovations in this building
  • 33:12and build out four floors and 100.
  • 33:14College we will be building
  • 33:16out floors in 101 college,
  • 33:19the School of Public Health will
  • 33:22be consolidating some of its.
  • 33:24Classroom space.
  • 33:25We will have backfill space related to
  • 33:29this work that we can then renovate.
  • 33:31This is the the.
  • 33:34Preparation for another building,
  • 33:36which is to move the School of
  • 33:39public health classrooms into 300
  • 33:42George temporarily so that we can.
  • 33:46Plan for a new building in this
  • 33:50strip mall area that's that's
  • 33:52now used for classrooms.
  • 33:53That will be very exciting.
  • 33:54It will allow us to cross bridges
  • 33:57here and what the students might
  • 33:59observe is that then you start to see
  • 34:02lines here over at Harkness Hall.
  • 34:04I think all of us know that Harkness
  • 34:07Hall is outlived its useful life and we
  • 34:10have plans to to renovate that eventually.
  • 34:13But you can see by the timeline that that's.
  • 34:16Getting passed when you guys are here.
  • 34:20Even I hope for the MD,
  • 34:21PhD students who are on the call.
  • 34:23So.
  • 34:24We also this December will convene
  • 34:27for the first time a scientific
  • 34:31Advisory Board comprised of,
  • 34:34you know, Nobel laureate,
  • 34:36several Lasker winners,
  • 34:38leaders in industry and interestingly I
  • 34:41think all but one have a Yale association,
  • 34:44maybe all of them do,
  • 34:46which was not something we know.
  • 34:48Charles Sawyers, I believe this is not,
  • 34:50not something we intended to do,
  • 34:52but happened by chance and and so we're
  • 34:54looking forward to seeking their advice.
  • 34:56On how we can do things a little bit better.
  • 35:00Lastly, looking at the clinical mission,
  • 35:03you know what academic health
  • 35:05systems have traditionally done.
  • 35:07Is offer access to cutting edge care,
  • 35:11whether that's chemotherapy or at Yale,
  • 35:14you know.
  • 35:15Closed loop insulin pumps,
  • 35:18transplant imaging,
  • 35:20etcetera.
  • 35:20But what increasingly academic health
  • 35:24systems are able to do is also offer
  • 35:28population health that increases
  • 35:30the health of our entire community.
  • 35:33And we have amazing physician nurses
  • 35:37staff in our academic health system.
  • 35:41One piece of evidence for that is that
  • 35:44we were among all of the hospitals in
  • 35:47the country in the top 24 for having
  • 35:50the lowest mortality rate during COVID.
  • 35:52And so I hold this out as an example of what
  • 35:56we can do when we are all working together.
  • 36:00It is not,
  • 36:01however,
  • 36:02always what we do,
  • 36:03and although we offer excellent care,
  • 36:07we often offer it in silos
  • 36:09and not in a coordinated way,
  • 36:11and we also often don't
  • 36:14measure what we're doing so
  • 36:16this. Slide which shows where we are in
  • 36:19NIH ranking and has a number of NR not
  • 36:22ranked and has a number of levels below
  • 36:2510 is not what Yale School of Medicine
  • 36:30or you only Haven Health should aspire
  • 36:33to and the reason for this is that.
  • 36:35As I say, we are not working together.
  • 36:37We're still working in silos.
  • 36:40We have tremendous opportunity when
  • 36:42you look at where we are represented
  • 36:45across the state of Connecticut.
  • 36:48The state of Connecticut has demographics
  • 36:50that mirror the rest of the country
  • 36:53and we have both some of the wealthiest
  • 36:56communities in the country as well as the
  • 36:59largest disparities in income in the country.
  • 37:03So as a.
  • 37:04Place where we can have impact
  • 37:07across a diverse set of communities.
  • 37:10This is a wonderful place to be.
  • 37:13And so we need to realize that ability to
  • 37:16improve health across all of our communities.
  • 37:19We also have a financial relationship
  • 37:21with our clinical enterprise.
  • 37:22We we support our research and our
  • 37:26educational mission in part through our
  • 37:29revenues from the clinical enterprise
  • 37:31and those have been growing and we
  • 37:34expect that they will not continue
  • 37:36to grow at that same rate rate.
  • 37:38So we have to work smarter.
  • 37:40One of the reasons is that we have an
  • 37:42aging population and and more of our
  • 37:46older patients are shifting from commercial.
  • 37:49Insurance tends to pay better to Medicare,
  • 37:51where hospitals often lose money
  • 37:54on the care of patients.
  • 37:56We also have lost some patients that
  • 37:59we think are the patients we should
  • 38:02see that is the patients in in.
  • 38:04Requiring tertiary and quaternary
  • 38:06care to hospitals that we feel are
  • 38:09less equipped to care for them,
  • 38:10and so we need to reverse that.
  • 38:13So we are engaging in a significant
  • 38:16effort around realigning this,
  • 38:18the School of Medicine and Neal New Haven
  • 38:22Health system as an academic health system.
  • 38:25Very grateful to have the
  • 38:27partnership of Chris O'Connor,
  • 38:29the CEO for Yale New Haven Health System.
  • 38:32And a number of people have been working on
  • 38:36this for the first time in memorable history.
  • 38:40We are developing a shared strategic plan.
  • 38:44And one of the things that I would
  • 38:46highlight is these are the pillars
  • 38:48that the group has identified and in
  • 38:51the highest ranking both among our,
  • 38:53our.
  • 38:53With medicine colleagues on this committee,
  • 38:56but also among our hospital members
  • 38:59of this committee,
  • 39:00leading Edge research was important
  • 39:02and and and actually came out on top.
  • 39:06But providing access to our patients,
  • 39:09you know,
  • 39:09you can provide the best possible care,
  • 39:11but if a patient can't access it,
  • 39:13it doesn't do them any good.
  • 39:16Providing exceptional value that
  • 39:18that allows all in the community
  • 39:22to benefit and then of course
  • 39:26cultivating our educational missions.
  • 39:29And so you'll see some of the cross
  • 39:32cutting foundational elements here.
  • 39:34We also are doing some work,
  • 39:36although I think this is an area
  • 39:38that we have much more work to do to
  • 39:41coordinate our operations where we have.
  • 39:45We're not working in parallel,
  • 39:47but we're working together.
  • 39:48So once we have that strategic plan,
  • 39:50we're following the same
  • 39:52data we're following.
  • 39:53We're not having duplication of
  • 39:55things that will allow us to provide
  • 39:58better service and also to be.
  • 40:03To lower expenses, frankly and and
  • 40:05these are some of the people that
  • 40:07will be involved in that work.
  • 40:09And then we're thinking about how we
  • 40:12align the physician practice plan beyond
  • 40:15medicine with the employed practice
  • 40:17plan NE Medical Group so that we are
  • 40:21working together and that a patient
  • 40:23is getting care that is seamless and
  • 40:26not fragmented and we have some very.
  • 40:30Significant work that you'll hear
  • 40:32about within the next two months
  • 40:35or so in which we're going to do
  • 40:37this and and stay tuned for that.
  • 40:40Lastly, we have to.
  • 40:43Make our funds flow between the hospital
  • 40:46and the School of Medicine rational.
  • 40:48This is a cartoon of the many,
  • 40:51many agreements we have back and forth,
  • 40:54which is crazy.
  • 40:55And so we're thinking about how do we
  • 40:58create a fund flow model that aligns
  • 41:01incentives and where people get paid
  • 41:03for their work and and it's not a one
  • 41:06off negotiation where it's fairly
  • 41:08formulaic and those things have a
  • 41:10huge impact on our ability to fund.
  • 41:13An educational system for example,
  • 41:15and and fund our research,
  • 41:17just say a little bit about finance.
  • 41:20I mentioned that Arnie Donton joined
  • 41:24in July of 2021 and discovered
  • 41:29why we recruited him,
  • 41:32which is that we have a lot of
  • 41:34work to do around getting seamless
  • 41:36processes in place and analytics
  • 41:38to enable our core missions.
  • 41:40And so this is his mission
  • 41:43statement and vision.
  • 41:44But when there's been
  • 41:46failure of those processes,
  • 41:48it has pretty dramatic consequences.
  • 41:52And so some of you are aware that
  • 41:54we had a $40 million theft over a
  • 41:56period of about 10 years dating back
  • 41:59to 2012 in one of our departments.
  • 42:01That cannot happen unless you have
  • 42:04failure in many places in the system.
  • 42:07It's it's not unlike this,
  • 42:09the safety analysis we do in the
  • 42:12hospital when there's been an adverse event.
  • 42:14And so it was everything from
  • 42:17oversight of individuals to how we
  • 42:19train people to how the controls work
  • 42:22that some of which are centralized
  • 42:24to how we could see the data.
  • 42:26And one of the things that our work in
  • 42:30correcting these has has highlighted
  • 42:33is around climate and the fact that
  • 42:36many of us don't feel like it's our
  • 42:39job to to pay attention to these things.
  • 42:41And it does seem mundane and.
  • 42:44It doesn't seem like it's
  • 42:46directly related to what you do,
  • 42:47but I will tell you that it it is.
  • 42:49And so you know,
  • 42:50these are some of the things
  • 42:52that we've heard from.
  • 42:55Senior faculty sometimes.
  • 42:57And my favorite is do you know who I am?
  • 43:00And you know,
  • 43:01there's an arrogance associated
  • 43:02with that that should never be
  • 43:03part of Yale School of Medicine.
  • 43:05And it goes back to what we were
  • 43:07talking about around professionalism.
  • 43:09While we're talking about money,
  • 43:10I will mention that we are in
  • 43:13the midst of a capital campaign.
  • 43:15One of the goals of that campaign is
  • 43:18to raise money for financial aid to
  • 43:21make our School of Medicine truly debt free.
  • 43:25We have had a decline in our.
  • 43:29That of our students are median
  • 43:32debt of our students is around
  • 43:35in this past year 79,000 compared
  • 43:38to a much higher number.
  • 43:40Average is more like 110,000 I believe
  • 43:44compared to a national average of about 204.
  • 43:47That should get the median should
  • 43:49get closer to 60 as we start
  • 43:52to realize the capping,
  • 43:53the benefit of capping the unit loan.
  • 43:55But of course we'd like to get
  • 43:58that number down to zero and so.
  • 44:00We we also have an opportunity to match funds
  • 44:03and create a quasi endowment to do that.
  • 44:06This takes time, but but it's a high
  • 44:09priority in our capital campaign.
  • 44:11And just to show you that we are starting
  • 44:14to reap the benefits of that campaign.
  • 44:16With an increase in in funding
  • 44:19over the last three years.
  • 44:21So I've talked about a lot of specific
  • 44:24elements around the three missions.
  • 44:27I would add the 4th mission,
  • 44:28which is how we develop people,
  • 44:30whether it's our students
  • 44:32or trainees or our faculty.
  • 44:33And I've shared with you some cross
  • 44:35cutting themes about how we will
  • 44:37do that to realize our vision.
  • 44:38I think we've allowed plenty of time
  • 44:40for questions and I will stop sharing.
  • 44:46Thank you so very much, Dean Brown.
  • 44:48If anyone has any questions, it's viewing.
  • 44:51I haven't seen any so far, but there
  • 44:52is an in the bottom part in the chat.
  • 44:55There should be a question and answer
  • 44:57area and people can put in their
  • 45:00questions and we can try to answer them.
  • 45:04Not seeing anything so far you.
  • 45:07People may may want to take a a
  • 45:09lunch break, so that's OK too.
  • 45:22While we're waiting to see if
  • 45:23anyone does have some questions
  • 45:24that they'd like to submit,
  • 45:25I'd just like to take the time
  • 45:27to thank you, Dean Brown,
  • 45:28again for coming and speaking.
  • 45:29It's always a pleasure to get to work
  • 45:31with you and to get to see all the
  • 45:33fantastic work that you and everyone
  • 45:34here is doing to try to further the
  • 45:36training and the opportunities and
  • 45:38the culture here at the schools.
  • 45:39Very inspiring.
  • 45:40So thank you very much.
  • 45:41You have a great team. So.
  • 45:44And and I and again thank you as you
  • 45:47know because we meet in the MSC,
  • 45:49but I I think that. You know,
  • 45:52one of the philosophies of the
  • 45:54old system is that you are future,
  • 45:57future colleagues and you very much,
  • 45:58the students are very much
  • 46:00been part of this effort. So.
  • 46:02Yes, that is. I very much felt that
  • 46:04and experience that myself and I know
  • 46:06many of my other classmates have,
  • 46:08so we're very excited about.
  • 46:11Question in the chat,
  • 46:12do you have any thoughts on
  • 46:14the future Yale Health CEO?
  • 46:15So many of you may have seen the
  • 46:17announcement that Paul Jennison is
  • 46:19stepping down and there's now a
  • 46:21national search for that position.
  • 46:24I I and Peg McGovern, our CEO of your
  • 46:28medicine is on that search committee.
  • 46:29I think we have tremendous opportunity.
  • 46:31It's a, it's a little bit
  • 46:34unusual to have a separate.
  • 46:36To have the the health plan for the
  • 46:40university separate from the faculty
  • 46:42practice plan to the extent that they are,
  • 46:46and I think we can.
  • 46:48We can work when the new leader
  • 46:51is in place in ways that will
  • 46:54increase efficiency and access
  • 46:56again for our university community,
  • 46:58at the same time making sure that
  • 47:01we're providing the best value
  • 47:03care about based care that we can.
  • 47:24You don't see any more questions
  • 47:26coming in at the moment,
  • 47:27but for the MSC perspectives,
  • 47:29our theme this year is equity and access
  • 47:31and it's fantastic just how much of
  • 47:33the schools principals align with that
  • 47:35based on what you've been speaking about
  • 47:37today and what our experiences have been.
  • 47:39So would like to tune in in the future.
  • 47:41We will be trying to continue on that theme
  • 47:44and look forward to the future
  • 47:45conversations. Thank you everybody.
  • 47:46Thank you so much.