1990
Conserved sequences in the U2 snRNA-encoding genes of Kinetoplastida do not include the putative branchpoint recognition region
Tschudi C, Williams S, Ullu E. Conserved sequences in the U2 snRNA-encoding genes of Kinetoplastida do not include the putative branchpoint recognition region. Gene 1990, 91: 71-77. PMID: 2401409, DOI: 10.1016/0378-1119(90)90164-m.Peer-Reviewed Original ResearchConceptsU2 small nuclear RNASmall nuclear RNAU2 genesEvolutionary conservationOrder KinetoplastidaConserved sequencesNuclear RNASequence variationFlanking regionsNuclear extractsRecognition sequenceKinetoplastidaUpstream elementRecognition regionGenesRNACorresponding sequenceLeishmania mexicana amazonensisSequenceT. congolenseTrypanosoma congolenseBiosynthesisNucleotidesProteinCongolense
1988
Polygene transcripts are precursors to calmodulin mRNAs in trypanosomes.
Tschudi C, Ullu E. Polygene transcripts are precursors to calmodulin mRNAs in trypanosomes. The EMBO Journal 1988, 7: 455-463. PMID: 3366120, PMCID: PMC454342, DOI: 10.1002/j.1460-2075.1988.tb02833.x.Peer-Reviewed Original ResearchConceptsCalmodulin mRNACultured procyclic trypanosomesAbundant RNA speciesSteady-state RNAPulse-labeled RNAAuthentic precursorIntergenic regionRNA speciesProcyclic trypanosomesCalmodulin genePolyadenylation sitesAfrican trypanosomesHybridization probesTranscriptsStreptavidin-agaroseDiscrete endsSmall familyTrypanosomesMRNAGenesRNASpeciesCalmodulinTrypanosoma brucei gambienseBrucei gambiense
1986
The U2 RNA analogue of Trypanosoma brucei gambiense: implications for a splicing mechanism in trypanosomes
Tschudi C, Richards F, Ullu E. The U2 RNA analogue of Trypanosoma brucei gambiense: implications for a splicing mechanism in trypanosomes. Nucleic Acids Research 1986, 14: 8893-8903. PMID: 3786140, PMCID: PMC311918, DOI: 10.1093/nar/14.22.8893.Peer-Reviewed Original ResearchConceptsU2 RNASpliced leader RNASingle-copy geneSignificant sequence homologyMaturation of mRNAMammalian counterpartsCopy geneU RNALeader RNASplicing mechanismSequence homologySecondary structureRNATrypanosomesGenesRNA analogSplicingHomologyTrypanosoma brucei gambiensePossible interactionsMRNABrucei gambienseMaturation
1985
Calmodulin genes in trypanosomes are tandemly repeated and produce multiple mRNAs with a common 5' leader sequence.
Tschudi C, Young A, Ruben L, Patton C, Richards F. Calmodulin genes in trypanosomes are tandemly repeated and produce multiple mRNAs with a common 5' leader sequence. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 3998-4002. PMID: 3858856, PMCID: PMC397921, DOI: 10.1073/pnas.82.12.3998.Peer-Reviewed Original Research
1984
Alu sequences are processed 7SL RNA genes
Ullu E, Tschudi C. Alu sequences are processed 7SL RNA genes. Nature 1984, 312: 171-172. PMID: 6209580, DOI: 10.1038/312171a0.Peer-Reviewed Original ResearchConceptsRNA genesAlu sequencesMiddle repetitive DNA sequencesAbundant cytoplasmic RNARepetitive DNA sequencesHuman 7SL RNAInsect sequencesAlu domainMammalian radiationDrosophila melanogasterEvolutionary distanceXenopus sequenceAbundant familyDNA sequencesNucleotide sequenceCDNA copyCytoplasmic RNAPair sequencePrimary structureProtein secretionRNAGenesHuman counterpartSequenceSignificant block