1998
Exonic Sequences in the 5′ Untranslated Region of α-Tubulin mRNA Modulate trans Splicing in Trypanosoma brucei
López-Estraño C, Tschudi C, Ullu E. Exonic Sequences in the 5′ Untranslated Region of α-Tubulin mRNA Modulate trans Splicing in Trypanosoma brucei. Molecular And Cellular Biology 1998, 18: 4620-4628. PMID: 9671472, PMCID: PMC109048, DOI: 10.1128/mcb.18.8.4620.Peer-Reviewed Original Research
1996
Trans -splicing in trypanosotnatid protozoa
Ullu E, Tschudi C, Gunzl A. Trans -splicing in trypanosotnatid protozoa. 1996, 115-133. DOI: 10.1093/oso/9780199636020.003.0007.Peer-Reviewed Original ResearchTrans splicingSplice siteT. brucei cellsPolycistronic pre-mRNARNA processing reactionsEnd of transcriptsDifferent variant surface glycoproteinsSeparate RNA moleculesVariant surface glycoproteinSL RNAList of organismsSmall RNAsBrucei cellsSL sequenceTrypanosomatid protozoaMature mRNALeader RNAMature speciesPre-mRNATrypanosoma bruceiRNA moleculesProcessing reactionsRNASurface glycoproteinFirst evidence
1993
Temporal order of RNA-processing reactions in trypanosomes: rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts.
Ullu E, Matthews K, Tschudi C. Temporal order of RNA-processing reactions in trypanosomes: rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts. Molecular And Cellular Biology 1993, 13: 720-725. PMID: 8417363, PMCID: PMC358950, DOI: 10.1128/mcb.13.1.720.Peer-Reviewed Original ResearchConceptsRNA-processing reactionsTrans splicingPre-mRNASplice sitePolycistronic transcription unitsSplice acceptor siteTrypanosome genesMRNA biogenesisTranscription unitTrypanosome mRNAsLeader RNATubulin transcriptsSplicingAlpha-tubulinPolyadenylationMRNA synthesisAcceptor sitesTrypanosomesTemporal orderMRNABiogenesisGenesTranscriptsRNAOrganismsTemporal Order of RNA-Processing Reactions in Trypanosomes: Rapid trans Splicing Precedes Polyadenylation of Newly Synthesized Tubulin Transcripts
Ullu E, Matthews K, Tschudi C. Temporal Order of RNA-Processing Reactions in Trypanosomes: Rapid trans Splicing Precedes Polyadenylation of Newly Synthesized Tubulin Transcripts. Molecular And Cellular Biology 1993, 13: 720-725. DOI: 10.1128/mcb.13.1.720-725.1993.Peer-Reviewed Original ResearchRNA-processing reactionsTrans splicingPre-mRNASplice sitePolycistronic transcription unitsRNA processing reactionsSplice acceptor siteTrypanosome genesMRNA biogenesisTranscription unitTrypanosome mRNAsLeader RNATubulin transcriptsSplicingPolyadenylationΒ-tubulinΑ-tubulinMRNA synthesisAcceptor sitesTrypanosomesTemporal orderMRNABiogenesis
1990
Destruction of U2, U4, or U6 small nuclear RNA blocks Trans splicing in trypanosome cells
Tschudi C, Ullu E. Destruction of U2, U4, or U6 small nuclear RNA blocks Trans splicing in trypanosome cells. Cell 1990, 61: 459-466. PMID: 1692263, DOI: 10.1016/0092-8674(90)90527-l.Peer-Reviewed Original ResearchConceptsTrans splicingU snRNAsPre-mRNAU6 small nuclear RNAU4/U6 snRNPsAlpha-tubulin transcriptsSmall nuclear RNAHigh molecular weight RNAMolecular weight RNASite-directed cleavageSL sequenceLeader RNATrypanosome cellsU6 snRNPsNuclear RNAU6 snRNATrypanosoma bruceiSplicing processSplicingWeight RNASnRNAEarly stepsRNAase HRNAIntrons