2019
Modulation of flagellar rotation in surface-attached bacteria: A pathway for rapid surface-sensing after flagellar attachment
Schniederberend M, Williams JF, Shine E, Shen C, Jain R, Emonet T, Kazmierczak BI. Modulation of flagellar rotation in surface-attached bacteria: A pathway for rapid surface-sensing after flagellar attachment. PLOS Pathogens 2019, 15: e1008149. PMID: 31682637, PMCID: PMC6855561, DOI: 10.1371/journal.ppat.1008149.Peer-Reviewed Original ResearchMeSH KeywordsBacterial ProteinsBiofilmsCyclic AMPFimbriae, BacterialFlagellaGene Expression Regulation, BacterialMonomeric GTP-Binding ProteinsMutationPhenotypePseudomonas aeruginosaSignal TransductionVirulenceConceptsFlagellar rotationSurface-attached bacteriaGram-negative opportunistic pathogen Pseudomonas aeruginosaOpportunistic pathogen Pseudomonas aeruginosaSwitch complex proteinsSingle polar flagellumBiofilm formationSurface-associated behaviorsSurface-associated structuresType IV piliPathogen Pseudomonas aeruginosaGenetic screenPolar flagellumTranscriptional programsBiofilm initiationComplex proteinsMutant bacteriaFlagellar attachmentSecond messengerP. aeruginosaFlhFBacteriaFlagellaPathwayAltered behavior
2013
Spatial and numerical regulation of flagellar biosynthesis in polarly flagellated bacteria
Kazmierczak BI, Hendrixson DR. Spatial and numerical regulation of flagellar biosynthesis in polarly flagellated bacteria. Molecular Microbiology 2013, 88: 655-663. PMID: 23600726, PMCID: PMC3654036, DOI: 10.1111/mmi.12221.Peer-Reviewed Original ResearchMeSH KeywordsBacteriaBacterial ProteinsFlagellaGene Expression Regulation, BacterialMacromolecular SubstancesMonomeric GTP-Binding ProteinsTrans-ActivatorsConceptsPolar flagellatesFlagellar assemblyProper cell divisionRotation of flagellaFlagellar biosynthesisFlagellation patternsGram-negative bacteriaPeritrichous flagellaOrganelle numberCell divisionCell biologyFlhGFlhFBacterial speciesBacterial cellsFlagellatesFlagellaDifferent bacteriaMechanistic insightsProteinBacteriaRecent findingsSpeciesSpecific activityDistinct patterns
2012
The GTPase Activity of FlhF Is Dispensable for Flagellar Localization, but Not Motility, in Pseudomonas aeruginosa
Schniederberend M, Abdurachim K, Murray TS, Kazmierczak BI. The GTPase Activity of FlhF Is Dispensable for Flagellar Localization, but Not Motility, in Pseudomonas aeruginosa. Journal Of Bacteriology 2012, 195: 1051-1060. PMID: 23264582, PMCID: PMC3571332, DOI: 10.1128/jb.02013-12.Peer-Reviewed Original ResearchConceptsFlagellar functionGTPase activityOpportunistic human pathogen Pseudomonas aeruginosaHuman pathogen Pseudomonas aeruginosaSignal recognition particlePathogen Pseudomonas aeruginosaSingle-cell assaysFlhF proteinFlagellar localizationFlagellar assemblyRecognition particleAbiotic environmentProtein dimerizationFlagellar rotationNucleotide bindingFlhFPoint mutantsSurface organellesSwimming motilityBacterial motilityP. aeruginosaBacillus subtilisPseudomonas aeruginosaEnzymatic activityHydrolytic activity
2006
FlhF Is Required for Swimming and Swarming in Pseudomonas aeruginosa
Murray TS, Kazmierczak BI. FlhF Is Required for Swimming and Swarming in Pseudomonas aeruginosa. Journal Of Bacteriology 2006, 188: 6995-7004. PMID: 16980502, PMCID: PMC1595508, DOI: 10.1128/jb.00790-06.Peer-Reviewed Original ResearchMeSH KeywordsBacterial ProteinsFlagellaFlagellinGene DeletionGene ExpressionMicroscopy, Electron, TransmissionMicroscopy, VideoMonomeric GTP-Binding ProteinsMovementPseudomonas aeruginosaTranscription, GeneticConceptsWild-type bacteriaAssembly of flagellaRod-shaped organismExpression of flagellinFlhF proteinFlagellar assemblyFlagellar genesFlagellar poleFlhFFlagellin expressionMonotrichous bacteriaDecreased transcriptionCell surfaceBacteria resultsBacteriaLiquid mediumTranscriptionFlagellaOrganismsProteinDifferent motility patternsAberrant placementPseudomonas aeruginosaMotilityExpression