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MHS Program Information

Program Requirements and Course Information

Requirements for MHS Degree

Thesis Committee and Thesis

A full-length original thesis, at the culmination of a two-year commitment to the program and based upon the required two-year research project, of approximately 50-60 pages in length and reviewed and approved by a three-person thesis committee. The applicant must indicate how the three-person MHS thesis committee will be arranged. One member must come from outside the department or program of the primary advisor. The advisor and applicant are required to accept persons proposed for this committee by the MHS Degree Advisory Committee. The final thesis must be presented to the three-person thesis committee in an open forum. After approval by student's MHS thesis committee & MHS Departmental Director, the final thesis must be submitted for review to the Office of Student Research by March 1 for degree conferral in May.

Individual Development Plan (IDP)

Submission of an Individual Development Plan (IDP), developed by the MHS candidate and mentor once at intake and once following year 1 of the program. This will be reviewed by OSR to ensure adequate preparation to begin the program and adequate progress.

Progress meetings
Meet with the thesis committee two to three times a year to evaluate if adequate progress is being made, and elicit suggestions for correction if adequate progress is not being made.
Prepare at least one manuscript for publication in a peer-reviewed journal.
Grand Rounds
Presentation at Grand Rounds/Departmental meetings (at least 1 per year).

Required core courses: A minimum of three courses is required for the degree, whether the applicant is conducting patient-oriented research, laboratory research or translational research. These are IMED 645 (Introduction to Biostatistics in Clinical Investigation); IMED 625 (Principles of Clinical Research); and an ethics component that applicants can choose between, of eitherIMED 630 (Ethical Issues in Biomedical Research) orSect Ed 501 (Responsible Conduct of Research).

Read more about the course descriptions.

For those conducting clinical research, possible alternative required courses for IMED 645 and IMED 625 are: Biostatistics and Clinical and Health Services Research Methods presented by the National Clinician Scholars Program.

Elective courses: At least two elective courses for each applicant are required. For those conducting laboratory or translational research, it is strongly recommended that CBB 740a, Clinical and Translational Informatics (selected seminars) be taken. Also, IMED 655 (Writing Your First Grant), should be taken if class size permits. Applicants are advised to speak with their thesis committee to choose electives best suited to their project and career goals.


Tuition for the degree is $28,000, of which $8,000 is required to be paid. At the time of application, it is required that each applicant indicate how this $8,000 will be paid. The balance ($28K-$8K) will either be a waived fee by the School of Medicine or can be supported by an NIH training grant from the responsible department.

Please contact Anne Kellett in the Office of Student Research for details regarding tuition.

Tuition Rebate and Refund Policy

For details on YSM’s refund policy, please review the Yale School of Medicine Bulletin.