Study Identifies New Cell Type That Triggers Deadly Allergic Reactions
For millions of Americans, contact with certain foods can cause anaphylaxis, a life-threatening allergic reaction. A new study has uncovered a previously unknown cell type that promotes the reaction and could be used to identify individuals who are most at risk.
Medical School Professor Runs Through All 169 Connecticut Towns
Edward Snyder, MD, professor of laboratory medicine, doesn’t run to win, but he does run for the crown of a king. Last March, Snyder achieved a goal 16 years in the making—running races in all 169 towns in Connecticut. Those few who complete the feat are crowned as royalty by his running club.
Stephanie Eisenbarth: Discovering the bigger picture
Stephanie Eisenbarth is an Associate Professor in the Immunology Faculty at Yale University. Her work has shown that the guanine nucleotide exchange factor Dock8 plays a role in the migration of a specific dendritic cell subset, and that when Dock8 is missing, some dendritic cells can no longer prime CD4+ T cells. Stephanie’s laboratory now focuses on understanding how T cell–driven pathology is initiated. We chatted with Stephanie to find out about her journey in science.Source: Journal of Experimental Medicine
Bringing Your Lab to the Operating Room
Dr. Joe El-Khoury of Laboratory Medicine at Yale reviews the clinical utility, analytical considerations, and operational aspects of intraoperative parathyroid hormone (ioPTH) testing to highlight the important role laboratories play in providing high quality of care while reducing cost to the system.Source: Medical Lab Management
Fighting the Cold Virus and Other Threats, Body Makes Trade-off, Says Study
A Yale research team has revealed how cells in different parts of the human airway vary in their response to the common cold virus. Their finding, published in Cell Reports, could help solve the mystery of why some people exposed to the cold virus get ill while others don’t, said the researchers.
Targeting vaccines more effectively
Migratory type 2 conventional dendritic cells (cDC2s) appear to induce an especially robust immune response to vaccination, making vaccines more effective. Stephanie C. Eisenbarth, MD, PhD, associate professor of laboratory medicine, of immunobiology, and of medicine, and colleagues investigated the process by which dendritic cells convey vaccine-delivered antigens to T cells in the lymph nodes, which in turn spur antibody production.Source: Medicine@Yale
Blood research receives recognition
Stephanie C. Eisenbarth, MD, PhD, associate professor of laboratory medicine, of immunobiology, and of medicine (immunology), has received the National Blood Foundation’s Award for Innovative Research, for work that has been instrumental in helping to determine why some patients become alloimmunized after transfusion.Source: Medicine@Yale
Deputy Deans of Scientific and Faculty Affairs Appointed
The School of Medicine announced the appointment of Linda K. Bockenstedt, MD, as deputy dean for faculty affairs, Brian R. Smith, MD, as deputy dean for scientific affairs (clinical departments), and Michael C. Crair, PhD, as deputy dean for scientific affairs (basic science departments), effective July 1, 2017.