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Research

Overview & Mission

The overarching research mission of our faculty is to advance fundamental biomedical science and translate new knowledge to advance patient care and public health. Research efforts in the department span a wide field of topics including chromatin regulation, stem cell biology, epilepsy and neural networks, substance use disorders, host-pathogen interactions, cancer development and progression, and human immune system function in health and disease. Our diverse faculty have broad and deep expertise in a wide variety of disciplines:

  • Structural biology
  • Neurobiology (epilepsy and substance use disorders)
  • Metabolomics
  • Immunobiology
  • Virology
  • Cancer Biology
  • Stem Cell Biology
  • Hematology
  • Machine Learning and Artificial Intelligence
  • Quantum Computing and Medical Informatics

Our faculty are highly interactive and collaborative both amongst ourselves and with the broader Yale faculty beyond departmental boundaries. In addition to the weekly Grand Rounds, a seminar series with invited speakers in basic and translational science, our faculty has monthly informal research presentations at faculty meetings, and an annual research retreat. Many faculty have formal links with the Cancer Center, and secondary appointments in basic science departments such as Immunobiology, Cell Biology, Cellular and Molecular Physiology, Molecular Biophysics and Biochemistry, Microbial Pathogenesis, and Genetics.

Residents have a wide array of choices for working with faculty members within the department or, alternately, with faculty outside the department. With inter-disciplinary research yielding great advances in science and medicine, our department is poised to lead the next generation of biomedicine. We welcome you to join us in this endeavor.