2004
Real-time quantitative RT-PCR identifies distinct c-RET, RET/PTC1 and RET/PTC3 expression patterns in papillary thyroid carcinoma
Rhoden KJ, Johnson C, Brandao G, Howe JG, Smith BR, Tallini G. Real-time quantitative RT-PCR identifies distinct c-RET, RET/PTC1 and RET/PTC3 expression patterns in papillary thyroid carcinoma. Laboratory Investigation 2004, 84: 1557-1570. PMID: 15502856, DOI: 10.1038/labinvest.3700198.Peer-Reviewed Original ResearchAdultCarcinoma, PapillaryChildExonsFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedNuclear Receptor CoactivatorsOncogene ProteinsOncogene Proteins, FusionPolymerase Chain ReactionProtein-Tyrosine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-retReceptor Protein-Tyrosine KinasesReverse Transcriptase Polymerase Chain ReactionRNA, MessengerThyroid NeoplasmsTranscription FactorsReal-Time Quantitative Reverse Transcription-PCR for Cyclin D1 mRNA in Blood, Marrow, and Tissue Specimens for Diagnosis of Mantle Cell Lymphoma
Howe JG, Crouch J, Cooper D, Smith BR. Real-Time Quantitative Reverse Transcription-PCR for Cyclin D1 mRNA in Blood, Marrow, and Tissue Specimens for Diagnosis of Mantle Cell Lymphoma. Clinical Chemistry 2004, 50: 80-87. PMID: 14633913, DOI: 10.1373/clinchem.2003.024695.Peer-Reviewed Original ResearchConceptsMantle cell lymphomaReal-time reverse transcription PCRCases of MCLCyclin D1 mRNAQuantitative RT-PCRLymphoproliferative diseaseReverse transcription-PCRCell lymphomaD1 mRNAMicroglobulin mRNADiagnosis of MCLTranscription-PCRCyclin D1 mRNA expressionB cell-specific markersCritical diagnostic markerReal-time quantitative RT-PCRD1 mRNA expressionTime quantitative reverse transcription PCRQuantitative reverse transcription PCROvert diseaseMarrow specimensAmbiguous immunophenotypeCD19 mRNAMalignant cellsTissue specimens
2003
Real-time Quantitative RT-PCR of Cyclin D1 mRNA in Mantle Cell Lymphoma: Comparison with FISH and Immunohistochemistry
Hui* P, Howe* J, Crouch J, Nimmakayalu M, Qumsiyeh MB, Tallini G, Flynn SD, Smith BR. Real-time Quantitative RT-PCR of Cyclin D1 mRNA in Mantle Cell Lymphoma: Comparison with FISH and Immunohistochemistry. Leukemia & Lymphoma 2003, 44: 1385-1394. PMID: 12952233, DOI: 10.1080/1042819031000079168.Peer-Reviewed Original ResearchCyclin D1Diagnosis, DifferentialFalse Negative ReactionsHumansImmunohistochemistryIn Situ Hybridization, FluorescenceLymphoma, B-CellLymphoma, Mantle-CellReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionRNA, MessengerRNA, NeoplasmSensitivity and SpecificityTranslocation, Genetic
1997
Epstein‐Barr virus suspension cell assay using in situ hybridization and flow cytometry
Crouch J, Leitenberg D, Smith B, Howe J. Epstein‐Barr virus suspension cell assay using in situ hybridization and flow cytometry. Cytometry 1997, 29: 50-57. PMID: 9298811, DOI: 10.1002/(sici)1097-0320(19970901)29:1<50::aid-cyto5>3.0.co;2-h.Peer-Reviewed Original Research
1989
SIMILAR EFFECTS OF CYCLOSPORINE AND VERAPAMIL ON LYMPHOKINE, INTERLEUKIN 2 RECEPTOR, AND PROTO-ONCOGENE EXPRESSION
WALZ G, ZANKER B, WIEDER K, HADRO E, MOSCOVITCH-LOPATIN M, SMITH B, STROM T. SIMILAR EFFECTS OF CYCLOSPORINE AND VERAPAMIL ON LYMPHOKINE, INTERLEUKIN 2 RECEPTOR, AND PROTO-ONCOGENE EXPRESSION. Transplantation 1989, 47: 331-333. PMID: 2645720, DOI: 10.1097/00007890-198902000-00029.Peer-Reviewed Original ResearchConceptsT cell activationT cell mitogenesisC-mycIL-2RCultures of peripheral blood mononuclear cellsIncrease of intracellular Ca2+Calcium channel blocking agentsPeripheral blood mononuclear cellsMitogen-activated T cellsExpression of IL-2REvents of T cell activationEarly events of T cell activationEffect of cyclosporineIntracellular Ca2+Interleukin-2 receptorP55 interleukin 2 receptorChannel blocking agentsConcentrations of verapamilBlood mononuclear cellsCalcium-independent pathwayClinically therapeutic levelsIL-2 gene expressionProto-oncogene expressionPhorbol myristate acetateIn vitro concentrationsVerapamil selectively inhibits expression of interleukin-2 messenger RNA in mitogen activated mononuclear blood cells.
Zanker B, Walz G, Wieder K, Moscovitch-Lopatin M, Smith B, Strom T. Verapamil selectively inhibits expression of interleukin-2 messenger RNA in mitogen activated mononuclear blood cells. Transplantation Proceedings 1989, 21: 85-7. PMID: 2784906.Peer-Reviewed Original Research
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