1992
Cardiopulmonary Bypass Induces Leukocyte-Platelet Adhesion
Rinder C, Bonan J, Rinder H, Mathew J, Hines R, Smith B. Cardiopulmonary Bypass Induces Leukocyte-Platelet Adhesion. Blood 1992, 79: 1201-1205. PMID: 1371416, DOI: 10.1182/blood.v79.5.1201.1201.Peer-Reviewed Original ResearchConceptsLeukocyte-platelet conjugatesCardiopulmonary bypassMonocyte-platelet conjugatesEnd of CPBStart of CPBActivation of monocytesAlpha-granule releaseGMP-140 expressionGranule membrane protein-140Time courseLeukocyte-platelet adhesionCD11b expressionMonocyte activationSurface CD11bWhole bloodGMP-140Surface expressionProtein 140Increased numberCD11bBypassMonocytesPlateletsPlatelet adhesionConjugatesCardiopulmonary bypass induces leukocyte-platelet adhesion
Rinder C, Bonan J, Rinder H, Mathew J, Hines R, Smith B. Cardiopulmonary bypass induces leukocyte-platelet adhesion. Blood 1992, 79: 1201-1205. DOI: 10.1182/blood.v79.5.1201.bloodjournal7951201.Peer-Reviewed Original ResearchLeukocyte-platelet conjugatesCardiopulmonary bypassMonocyte-platelet conjugatesEnd of CPBStart of CPBActivation of monocytesAlpha-granule releaseGMP-140 expressionGranule membrane protein-140Time courseLeukocyte-platelet adhesionCD11b expressionMonocyte activationSurface CD11bWhole bloodGMP-140Surface expressionProtein 140Increased numberCD11bBypassMonocytesPlateletsPlatelet adhesionConjugates
1991
Modulation of Platelet Surface Adhesion Receptors during Cardiopulmonary Bypass
Rinder C, Mathew J, Rinder H, Bonan J, Ault K, Smith B. Modulation of Platelet Surface Adhesion Receptors during Cardiopulmonary Bypass. Anesthesiology 1991, 75: 563-570. PMID: 1718190, DOI: 10.1097/00000542-199110000-00004.Peer-Reviewed Original ResearchConceptsIIb/IIIaCardiopulmonary bypassGlycoprotein IIb/IIIaPlatelet activationQualitative platelet defectsGlycoprotein IVGlycoprotein IbAlpha-granule releaseGranule membrane protein-140Surface glycoprotein IbHLA APlatelet functionBaseline valuesVon Willebrand factor receptorBypassThrombospondin receptorGlycoprotein Ib expressionFlow cytometryIb expressionPlatelet defectsSelective decreasePlatelet receptorsFactor receptorReceptorsProtein 140