2025
Gambling in Connecticut adolescents: Prevalence, socio-demographic characteristics, trauma exposure, suicidality, and other risk behaviors
Stefanovics E, Zhai Z, Potenza M. Gambling in Connecticut adolescents: Prevalence, socio-demographic characteristics, trauma exposure, suicidality, and other risk behaviors. PLOS ONE 2025, 20: e0290589. PMID: 39908256, PMCID: PMC11798454, DOI: 10.1371/journal.pone.0290589.Peer-Reviewed Original ResearchConceptsSocial supportRisk behaviorsCorrelates of gamblingTraumatic experiencesPoor health outcomesAssociated with traumatic experiencesImplement tailored interventionsReceipt of social supportHealth risk behaviorsConnecticut high school studentsSocio-demographic characteristicsFamily social supportAcademic performanceAssociated with suicideInfluence gambling behaviorPublic health concernTailored interventionsHealth outcomesPast-year gamblingYouth Risk Behavior SurveyPoor academic performanceTrauma exposureRisk Behavior SurveyCurrent prevalenceHigh school studentsAbsenteeism Among Healthcare Workers: Job Grade and Other Factors That Matter in Sickness Absence
Sakr C, Fakih L, Musharrafieh U, Khairallah G, Makki M, Doudakian R, Tamim H, Redlich C, Slade M, Rahme D. Absenteeism Among Healthcare Workers: Job Grade and Other Factors That Matter in Sickness Absence. International Journal Of Environmental Research And Public Health 2025, 22: 127. PMID: 39857580, PMCID: PMC11764580, DOI: 10.3390/ijerph22010127.Peer-Reviewed Original ResearchConceptsSick leave episodesHealthcare workersSick leavePredictors of sick leaveHealth-related predictorsPoor health outcomesHigher sickness absenteeismJob gradeNegative binomial regression analysisAdequate patient careBinomial regression analysisHealth inequalitiesHealth outcomesHealth recordsSickness absenceDisrupt workflowPatient careTertiary medical centerSickness absenteeismWork-relatedSocio-economic factorsMedical conditionsMedical CenterFemale sexInvestigate predictors
2024
Sleep Deficiency in Young Children
Ordway M, Logan S, Sutton E. Sleep Deficiency in Young Children. Sleep Medicine Clinics 2024, 19: 549-557. PMID: 39455176, DOI: 10.1016/j.jsmc.2024.07.004.Peer-Reviewed Original ResearchConceptsSleep healthPoor health outcomesBehavioral sleep interventionsChildren's sleep healthSleep deficiencyHealth disparitiesPublic health concernHealth outcomesPediatric sleep researchMental healthSocioecological influencesSleep interventionsMultidimensional constructYoung ChildrenSleep disordersHealthSocioecological factorsHealth concernSleep researchEarly childhoodEarly lifeSampling methodAssociated riskDeficiencyAssociation between childhood abuse and risk of post-COVID-19 conditions: Results from three large prospective cohort studies
Vyas C, Wang S, Menor A, Kubzansky L, Slopen N, Rich-Edwards J, Chavarro J, Kang J, Roberts A. Association between childhood abuse and risk of post-COVID-19 conditions: Results from three large prospective cohort studies. Brain Behavior And Immunity 2024, 123: 143-150. PMID: 39191351, PMCID: PMC11698154, DOI: 10.1016/j.bbi.2024.08.046.Peer-Reviewed Original ResearchPost-COVID-19 conditionPost-COVID conditionsHealth-relatedPhysical/emotional abusePsychological factorsRisk of poor health outcomesGrowing Up Today StudyNurses' Health StudyPoor health outcomesAssociated with riskAssociated with increased riskChildhood abusePost-COVID-19COVID-19 surveyCOVID-19 questionnaireHealth outcomesHealth StudyProspective studyEmotional abuse subscaleSexual abuseSelf-reportCohort studyNo childhood abuseCOVID-19-related symptomsToday StudyThe Impact of Food Insecurity on the Management and Survival of Stage I-III Esophageal Cancer
Papageorge M, Potter A, Auchincloss H, Sachdeva U, Yang C, Schumacher L. The Impact of Food Insecurity on the Management and Survival of Stage I-III Esophageal Cancer. Annals Of Thoracic Surgery Short Reports 2024, 2: 524-527. PMID: 39790405, PMCID: PMC11708528, DOI: 10.1016/j.atssr.2024.02.002.Peer-Reviewed Original ResearchCancer careFood insecurityStage I-III esophageal cancerAssociated with poor health outcomesImpact of food insecurityFood insecurity interventionsPoor health outcomesEsophageal cancerEsophageal cancer careFood insecurity ratesReceipt of surgeryCox proportional hazards modelsMultinomial logistic regressionHealth outcomesProportional hazards modelNon-HispanicSurgical interventionMultivariate Cox proportional hazards modelSignificant disparitiesReduce inequalitiesLogistic regressionCancer-specific survivalStage III diseaseCompared to patientsSurvival of patientsPoor self‐rated health is associated with faster cognitive decline and greater small vessel disease in older adults with type 2 diabetes
Ramsingh N, Lin H, Ouyang Y, Ravona‐Springer R, Livny A, Soleimani L, Bendlin B, Meir M, Heymann A, Sano M, Azuri J, Beeri M. Poor self‐rated health is associated with faster cognitive decline and greater small vessel disease in older adults with type 2 diabetes. Diabetes/Metabolism Research And Reviews 2024, 40: e3761. PMID: 38287720, DOI: 10.1002/dmrr.3761.Peer-Reviewed Original ResearchConceptsLower self-rated healthSelf-rated healthOlder adultsCognitive domainsAssociation of self-rated healthBaseline self-rated healthPoor self-rated healthHigher self-rated healthGlobal cognitionCognitive declineAssociated with faster cognitive declineExecutive functionCognitive Decline studyPoor health outcomesFaster cognitive declineAssociated with cognitive declineMulti-morbidityHealth outcomesIsrael DiabetesType 2 diabetes mellitusType 2 diabetesAssociated with higher volumeDecline studiesAttention/working memoryEpisodic memory
2023
Poor self‐rated health is associated with faster cognitive decline and greater small vessel disease in older adults with type 2 diabetes
Ramsingh N, Lin H, Ouyang Y, Ravona‐Springer R, Livny A, Soleimani L, Bendlin B, Ben‐Meir M, Heymann A, Sano M, Azuri J, Beeri M. Poor self‐rated health is associated with faster cognitive decline and greater small vessel disease in older adults with type 2 diabetes. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.072883.Peer-Reviewed Original ResearchOlder adultsCognitive domainsCognitive declineExecutive functionPoor self-rated healthType 2 diabetesGlobal cognitionAssociated with faster cognitive declineSelf-rated healthCognitive Decline studyPoor health outcomesFaster cognitive declineTotal gray matterAssociated with cognitive declineMulti-morbidityHealth outcomesIsrael DiabetesAttention/working memoryEpisodic memoryBrain characteristicsAssociated with higher volumeMethod ParticipantsDecline studiesCognitive impairmentCognitionBeyond MACE: a multidimensional approach to outcomes in clinical trials for older adults with stable ischemic heart disease
Kalra K, Moumneh M, Nanna M, Damluji A. Beyond MACE: a multidimensional approach to outcomes in clinical trials for older adults with stable ischemic heart disease. Frontiers In Cardiovascular Medicine 2023, 10: 1276370. PMID: 38045910, PMCID: PMC10690830, DOI: 10.3389/fcvm.2023.1276370.Peer-Reviewed Original ResearchStable ischemic heart diseaseIschemic heart diseaseClinical trialsOlder adult populationOlder adultsHeart diseaseHealth outcomesAdult populationMajor adverse cardiovascular outcomesHigh cardiovascular riskAdverse cardiovascular outcomesMultiple chronic diseasesPatient-centered approachCardiovascular clinical trialsPoor health outcomesMore effective careQuality of lifeHolistic health outcomesCardiovascular outcomesCardiovascular riskGeriatric syndromesRandomized trialsPatient populationPatient preferencesChronic diseasesSex‐Specific Associations of Obstructive Sleep Apnea Risk With Patient Characteristics and Functional Outcomes After Acute Myocardial Infarction: Evidence From the VIRGO Study
Gupta A, Barthel A, Mahajan S, Dreyer R, Yaggi H, Bueno H, Lichtman J, Krumholz H. Sex‐Specific Associations of Obstructive Sleep Apnea Risk With Patient Characteristics and Functional Outcomes After Acute Myocardial Infarction: Evidence From the VIRGO Study. Journal Of The American Heart Association 2023, 12: e027225. PMID: 37702090, PMCID: PMC10547292, DOI: 10.1161/jaha.122.027225.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaAcute myocardial infarctionHigh OSA riskOSA riskSex-specific associationsFunctional outcomeHealth statusHigh riskVIRGO StudyMyocardial infarctionDepressive symptomsHistory of OSATime of AMIImpact of OSAObstructive sleep apnea riskLow-risk patientsSleep apnea riskMajority of patientsTime of presentationSex-specific outcomesWorse health statusHigh-risk menPoor health statusMental health statusPoor health outcomesImpact of childhood maltreatment on adult resilience
Li C, Lv G, Liu B, Ju Y, Wang M, Dong Q, Sun J, Lu X, Zhang L, Wan P, Guo H, Zhao F, Liao M, Zhang Y, Li L, Liu J. Impact of childhood maltreatment on adult resilience. BMC Psychiatry 2023, 23: 637. PMID: 37648984, PMCID: PMC10470179, DOI: 10.1186/s12888-023-05124-w.Peer-Reviewed Original ResearchConceptsMajor depressive disorder groupsMajor depressive disorderChildhood Trauma QuestionnaireChildhood maltreatmentEmotional neglectAdult resiliencePhysical neglectEmotional abuseHealthy controlsChildhood Trauma Questionnaire total scoreHC groupImpact of childhood maltreatmentCD-RISCSevere childhood maltreatmentAssociated with poor health outcomesConnor-Davidson Resilience ScaleScores of CD-RISCDepressive disorderPoor health outcomesTrauma QuestionnairePoor mental healthPsychiatric hospitalOptimality scoreTraumatized peopleFactor scoresWhat Do We Know About Interventions to Reduce Intersectional Stigma and Discrimination in the Context of HIV? A Systematic Review
Stangl A, Atkins K, Leddy A, Sievwright K, Sevelius J, Lippman S, Veras M, Zamudio-Haas S, Smith M, Pachankis J, Logie C, Rao D, Weiser S, Nyblade L. What Do We Know About Interventions to Reduce Intersectional Stigma and Discrimination in the Context of HIV? A Systematic Review. Stigma And Health 2023, 8: 393-408. DOI: 10.1037/sah0000414.Peer-Reviewed Original ResearchContext of HIVIntersectional stigmaSystematic reviewHuman immunodeficiency virus (HIV) stigmaMeta-Analyses (PRISMA) guidelinesPoor health outcomesPreferred Reporting ItemsStigma reduction interventionsPositive intervention effectsStigma domainsReporting ItemsHealth outcomesHIVSexual healthReduction interventionsAspects of stigmaMajority of studiesMost interventionsIntervention effectsStigma measuresInterventionOutcomesStigma outcomesStructural interventionsStigmaDesign, implementation and preliminary results of a type-2 hybrid cluster-randomized trial of integrating screening and treatment for major depressive disorder into specialty clinics providing opioid agonist therapies in Ukraine
Machavariani E, Bromberg D, Dumchev K, Dvoriak S, Zeziulin O, Morozova O, Esserman D, Pykalo I, Saichuk N, Ivasiy R, Haddad M, Altice F. Design, implementation and preliminary results of a type-2 hybrid cluster-randomized trial of integrating screening and treatment for major depressive disorder into specialty clinics providing opioid agonist therapies in Ukraine. Contemporary Clinical Trials 2023, 131: 107248. PMID: 37263492, PMCID: PMC10527419, DOI: 10.1016/j.cct.2023.107248.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyMajor depressive disorderCo-occurring disordersAgonist therapyDepressive disorderSpecialty clinicPsychiatric disordersPatient-level outcomesPrevalent psychiatric disordersCluster-randomized trialPoor health outcomesProvider-level dataMDD treatmentTreatment algorithmExperimental armHigh prevalenceDelivery outcomesHealth outcomesSerial surveysClinicPatientsProject ECHOSubstance useMonthsDisordersCo-occurring Medical Multimorbidity, Mental Illness, and Substance Use Disorders Among Older Criminal Legal System-Involved Veterans
Han B, Bronson J, Washington L, Yu M, Kelton K, Tsai J, Finlay A. Co-occurring Medical Multimorbidity, Mental Illness, and Substance Use Disorders Among Older Criminal Legal System-Involved Veterans. Medical Care 2023, 61: 477-483. PMID: 37204150, PMCID: PMC10330246, DOI: 10.1097/mlr.0000000000001864.Peer-Reviewed Original ResearchConceptsMedical multimorbidityMental illnessOlder veteransCLS involvementCo-occurring mental illnessVeterans Health Administration facilitiesMultivariable logistic regression modelConcurrent mental illnessPatterns of multimorbidityDisease-specific carePoor health outcomesSubstance use disordersLogistic regression modelsHigh prevalenceHigh riskLow prevalenceMultimorbidityAppropriate careUse disordersHealth outcomesIllnessAdministration facilitiesPrevalenceHealth recordsVeteransHierarchical Development of Physical Frailty and Cognitive Impairment and Their Association With Incident Cardiovascular Disease
Damluji A, Ijaz N, Chung S, Xue Q, Hasan R, Batchelor W, Orkaby A, Kochar A, Nanna M, Roth D, Walston J, Resar J, Gerstenblith G. Hierarchical Development of Physical Frailty and Cognitive Impairment and Their Association With Incident Cardiovascular Disease. JACC Advances 2023, 2: 100318. PMID: 37538136, PMCID: PMC10399211, DOI: 10.1016/j.jacadv.2023.100318.Peer-Reviewed Original ResearchMajor adverse cardiovascular eventsAdverse cardiovascular eventsCognitive impairmentCardiovascular eventsCardiovascular outcomesCardiovascular riskCardiovascular diseaseIncident major adverse cardiovascular eventsOlder adultsAdverse cardiovascular outcomesIncident cardiovascular diseasePhysical frailty phenotypeCoronary artery diseaseMultiple chronic conditionsPoor health outcomesAging Trends StudyFrailty phenotypeArtery diseasePrimary outcomeGeriatric conditionsChronic conditionsNational HealthPhysical frailtyStudy populationHigh riskNeonatal Intensive Care Unit Latent Profiles of Maternal Distress: Associations With 5-Year Maternal and Child Mental Health Outcomes
Njoroge W, Gerstein E, Lean R, Paul R, Smyser C, Rogers C. Neonatal Intensive Care Unit Latent Profiles of Maternal Distress: Associations With 5-Year Maternal and Child Mental Health Outcomes. Journal Of The American Academy Of Child & Adolescent Psychiatry 2023, 62: 1123-1133. PMID: 37084882, PMCID: PMC10543383, DOI: 10.1016/j.jaac.2023.02.015.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitChild mental health outcomesPreterm infantsHealth outcomesMental health outcomesNICU stressReference listsHealth factorsSocial determinantsChildren age 5 yearsHigher depressionIntensive care unitLife stressDisparate health outcomesPoor health outcomesAge 5 yearsEthnic groupsNICU dischargeCare unitRisk dyadsChildren ages 5Clinical riskUniversal screeningMaternal symptomatologyAffective symptomsThe use of hotels/motels to address homelessness among veterans during the COVID-19 pandemic: lessons from the supportive services for veteran families program
Montgomery A, Zickmund S, Byrne T, Galyean P, Suo Y, Pettey W, Velasquez T, Gelberg L, Kertesz S, Tsai J, Nelson R. The use of hotels/motels to address homelessness among veterans during the COVID-19 pandemic: lessons from the supportive services for veteran families program. Journal Of Social Distress And The Homeless 2023, 33: 305-315. DOI: 10.1080/10530789.2023.2187522.Peer-Reviewed Original ResearchHotels/motelsQualitative interviewsCOVID-19 pandemicSupportive servicesHousing instabilityProgrammatic responsesVeteran householdsFinancial assistanceHomelessnessFamilies ProgramService leadershipVulnerable groupsOngoing public health concernProgram providersPoor health outcomesMethods studyVulnerable populationsCOVID-19InterviewsMotelsQuantitative dataAssistanceServicesPandemicPolicyExploring the Relationship between Debt and Health after Incarceration: a Survey Study
Ginapp C, Aminawung J, Harper A, Puglisi L. Exploring the Relationship between Debt and Health after Incarceration: a Survey Study. Journal Of Urban Health 2023, 100: 181-189. PMID: 36650355, PMCID: PMC9918653, DOI: 10.1007/s11524-022-00707-6.Peer-Reviewed Original Research
2022
The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological research
Steffens D, Fahed M, Manning K, Wang L. The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological research. Translational Psychiatry 2022, 12: 525. PMID: 36572691, PMCID: PMC9792580, DOI: 10.1038/s41398-022-02292-3.Peer-Reviewed Original ResearchConceptsPrefrontal cortex circuitCortex circuitPeripheral biomarkersPresence of apathyNeurobiology of apathyPoor health outcomesDefinitive treatmentFuture studiesApathy symptomsClinical managementNeuropsychiatric comorbiditiesFunctional declineCommon conditionNeurocognitive impairmentCognitive disordersNeuropsychological featuresHealth outcomesCognitive impairmentBrain circuitryNeuropsychiatric disordersPrefrontal cortexOlder adultsClinical realityBiomarker researchImpairmentInsomnia and Other Sleep Disorders in Older Adults
Cohen Z, Eigenberger P, Sharkey K, Conroy M, Wilkins K. Insomnia and Other Sleep Disorders in Older Adults. Psychiatric Clinics Of North America 2022, 45: 717-734. PMID: 36396275, DOI: 10.1016/j.psc.2022.07.002.Peer-Reviewed Original ResearchNicotine dose-dependent epigenomic-wide DNA methylation changes in the mice with long-term electronic cigarette exposure.
Peng G, Xi Y, Bellini C, Pham K, Zhuang ZW, Yan Q, Jia M, Wang G, Lu L, Tang MS, Zhao H, Wang H. Nicotine dose-dependent epigenomic-wide DNA methylation changes in the mice with long-term electronic cigarette exposure. American Journal Of Cancer Research 2022, 12: 3679-3692. PMID: 36119846, PMCID: PMC9442002.Peer-Reviewed Original ResearchElectronic cigarette exposureCigarette exposureMale ApoE-/- miceApoE-/- miceCytokine mRNA expressionPoor health outcomesWhite blood cellsElectronic cigarette useDose-dependent mannerE-cigarette aerosolAerosol inhalationCigarette smokingActivation of MAPKHigher nicotine concentrationsMAPK pathway activationCell-damaging effectsCpG sitesHealth outcomesCigarette useMRNA expressionNicotine concentrationsPathway activationSignificant CpG sitesBlood cellsSignificant alterations
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