2024
Reprint of: Sex differences in appeal, reward, and sensory experience of E-cigarette flavors among adults who smoke cigarettes
Davis D, Buta E, Green B, Krishnan-Sarin S. Reprint of: Sex differences in appeal, reward, and sensory experience of E-cigarette flavors among adults who smoke cigarettes. Preventive Medicine 2024, 188: 108114. PMID: 39232940, DOI: 10.1016/j.ypmed.2024.108114.Peer-Reviewed Original ResearchDrug Effects QuestionnaireE-cigarette appealLabeled Hedonic ScaleGeneral Labeled Magnitude ScaleSensory experienceEffects of sexSex differencesRewardEffective questionnairesExploratory analysisE-cigarette flavorsNicotine concentrationsE-cigarettesSmoking cigarettesE-cigarette experienceLinear mixed modelsEffects of e-cigarettesIntensity of flavorMenthol flavorsAdultsSexScaleCuesCigaretteHedonic scaleSex differences in appeal, reward, and sensory experience of E-cigarette flavors among adults who smoke cigarettes
Davis D, Buta E, Green B, Krishnan-Sarin S. Sex differences in appeal, reward, and sensory experience of E-cigarette flavors among adults who smoke cigarettes. Preventive Medicine 2024, 185: 108040. PMID: 38866212, PMCID: PMC11323236, DOI: 10.1016/j.ypmed.2024.108040.Peer-Reviewed Original ResearchDrug Effects QuestionnaireE-cigarette appealLabeled Hedonic ScaleGeneral Labeled Magnitude ScaleSensory experienceEffects of sexSex differencesRewardEffective questionnairesExploratory analysisE-cigarette flavorsNicotine concentrationsE-cigarettesSmoking cigarettesE-cigarette experienceIntensity of flavorLinear mixed modelsMenthol flavorsEffects of e-cigarettesAdultsSexScaleHedonic scaleCigaretteCuesHow healthcare providers and the right information may play a critical role in quitting success among smokers interested in using e-cigarettes for quitting: Results from a survey of U.S adults
Sharma A, King J, Krishnan-Sarin S, O’Malley S, Morean M, Bold K. How healthcare providers and the right information may play a critical role in quitting success among smokers interested in using e-cigarettes for quitting: Results from a survey of U.S adults. PLOS ONE 2024, 19: e0303245. PMID: 38753868, PMCID: PMC11098412, DOI: 10.1371/journal.pone.0303245.Peer-Reviewed Original ResearchConceptsHealthcare providersQuit smokingE-cigarettesBenefits of e-cigarettesPromote smoking cessationPotential public health benefitsGlobal public health priorityPublic health priorityReduce cigarette smokingIncrease quit ratesSmoking cessation attemptsCessation supportNicotine concentrationsHealth prioritySource of informationQuit ratesUS adultsU.S adultsSmoking cessationQuit successCessation attemptsHealthcareProvidersSmokingCigarette smoking
2022
Chronic oral nicotine exposure decreases aversive taste of nicotine, increases nicotine withdrawal and reinstatement, but cherry flavor does not alter nicotine’s effects in adolescent rats
Bagdas D, Harris L, Addy N. Chronic oral nicotine exposure decreases aversive taste of nicotine, increases nicotine withdrawal and reinstatement, but cherry flavor does not alter nicotine’s effects in adolescent rats. Neuroscience Letters 2022, 793: 137008. PMID: 36476758, PMCID: PMC9948648, DOI: 10.1016/j.neulet.2022.137008.Peer-Reviewed Original ResearchConceptsTaste responsesNicotine concentrationsNicotine exposureNicotine withdrawalNicotine effectsAdolescent ratsChronic exposureOral nicotine exposureTaste reactivityAversive tasteChronic nicotine exposureDevelopment of toleranceLow nicotine concentrationsE-cigarette useE-cigarette flavoringsHigher nicotine concentrationsNicotine abstinenceNicotine useNaïve animalsChronic effectsNicotineRatsAversive responsesDifferent nicotine concentrationsWithdrawalE-cigarette Use Patterns, Flavors, and Device Characteristics Associated With Quitting Smoking Among a U.S. sample of Adults Using E-cigarettes in a Smoking Cessation Attempt
Bold K, O’Malley S, Krishnan-Sarin S, Morean M. E-cigarette Use Patterns, Flavors, and Device Characteristics Associated With Quitting Smoking Among a U.S. sample of Adults Using E-cigarettes in a Smoking Cessation Attempt. Nicotine & Tobacco Research 2022, 25: 954-961. PMID: 36462196, PMCID: PMC10077943, DOI: 10.1093/ntr/ntac276.Peer-Reviewed Original ResearchConceptsE-cigarette useE-cigarettesTobacco regulatory policyLonger durationNicotine concentrationsAbstinence durationNon-tobacco flavorsMultivariable linear regression modelsSmoking cessation attemptE-cigarette use patternsDuration of abstinenceLonger abstinence durationCessation successSmoking cessationCigarette cessationQuitting smokingMultivariable modelCessation attemptsQuit attemptsE-cigarette flavorsSmokingAverage durationAbstinenceAdultsPublic healthNicotine dose-dependent epigenomic-wide DNA methylation changes in the mice with long-term electronic cigarette exposure.
Peng G, Xi Y, Bellini C, Pham K, Zhuang ZW, Yan Q, Jia M, Wang G, Lu L, Tang MS, Zhao H, Wang H. Nicotine dose-dependent epigenomic-wide DNA methylation changes in the mice with long-term electronic cigarette exposure. American Journal Of Cancer Research 2022, 12: 3679-3692. PMID: 36119846, PMCID: PMC9442002.Peer-Reviewed Original ResearchElectronic cigarette exposureCigarette exposureMale ApoE-/- miceApoE-/- miceCytokine mRNA expressionPoor health outcomesWhite blood cellsElectronic cigarette useDose-dependent mannerE-cigarette aerosolAerosol inhalationCigarette smokingActivation of MAPKHigher nicotine concentrationsMAPK pathway activationCell-damaging effectsCpG sitesHealth outcomesCigarette useMRNA expressionNicotine concentrationsPathway activationSignificant CpG sitesBlood cellsSignificant alterationsUse and Product Characteristics of “Tobacco Free Nicotine” E-Cigarettes Among Young Adults
Davis DR, Bold KW, Camenga D, Kong G, Jackson A, Lee J, Rajesh-Kumar L, Krishnan-Sarin S, Morean ME. Use and Product Characteristics of “Tobacco Free Nicotine” E-Cigarettes Among Young Adults. Nicotine & Tobacco Research 2022, 25: 379-385. PMID: 35913677, PMCID: PMC9910142, DOI: 10.1093/ntr/ntac188.Peer-Reviewed Original ResearchConceptsE-cigarette useFrequent e-cigarette useE-cigarettesYoung adultsAdjusted modelMore frequent e-cigarette useNicotine pouchesMultivariable adjusted modelsE-cigarette use statusNicotine e-cigarettesLogistic regression modelsBinary logistic regression modelRace/ethnicityU.S. young adultsOnset ageYounger ageBivariate comparisonsNicotine concentrationsTobacco productsAlcohol useAdultsFree nicotineUse statusLifetime frequencyLifetime e-cigarette useGenotypic Differences in the Effects of Menthol on Nicotine Intake and Preference in Mice
Akinola LS, Rahman Y, Ondo O, Gonzales J, Bagdas D, Jackson A, Davidson-Wert N, Damaj MI. Genotypic Differences in the Effects of Menthol on Nicotine Intake and Preference in Mice. Frontiers In Neuroscience 2022, 16: 905330. PMID: 35769694, PMCID: PMC9234577, DOI: 10.3389/fnins.2022.905330.Peer-Reviewed Original ResearchOral nicotine consumptionEffect of mentholD2J miceMenthol effectsNicotine consumptionΑ7 nAChRsDifferential effectsTwo-bottle choiceTAAR1 geneOral aversionC57BL/6J miceNicotine rewardSystemic administrationNicotine intakeDBA/2J miceB6J micePharmacological responseNicotine addictionGenotype-specific mechanismsNicotine concentrationsMiceMouse strainsBasal preferenceGenetic factorsNicotine
2018
Psychometric Evaluation of the E-cigarette Dependence Scale
Morean M, Krishnan-Sarin S, Sussman S, Foulds J, Fishbein H, Grana R, O’Malley S. Psychometric Evaluation of the E-cigarette Dependence Scale. Nicotine & Tobacco Research 2018, 21: 1556-1564. PMID: 29301008, PMCID: PMC6821314, DOI: 10.1093/ntr/ntx271.Peer-Reviewed Original ResearchConceptsE-cigarette useE-cigarette dependence scalesE-cigarettesE-cigarette usersE-cigarette dependenceNicotine dependenceCigarette smoking statusCurrent cigarette smoking statusDaily e-cigarette usersDependence ScaleExclusive e-cigarette usersConvergent validityLiquid nicotine contentSmoking statusCigarette smokersQuit attemptsLeast weeklyNicotine concentrationsUse outcomesPsychometric evaluationTest-criterion relationshipsCigarettesAnonymous surveyStrong psychometric propertiesSmokers
2017
Electronic cigarette use among individuals with a self‐reported eating disorder diagnosis
Morean M, L'Insalata A. Electronic cigarette use among individuals with a self‐reported eating disorder diagnosis. International Journal Of Eating Disorders 2017, 51: 77-81. PMID: 29076176, DOI: 10.1002/eat.22793.Peer-Reviewed Original ResearchConceptsEating disordersSelf-reportED historyNicotine concentrationsNegative affectTreatment providersE-cigarettesLose/control weightPrimary study aimE-cigarette useAmerican adultsED treatmentElectronic cigarette useCigarette useNicotineParticipantsAdult vapersIndividualsStudy aimAnonymous surveyAffectHealth concernDisordersTreatmentClientsStudying the interactive effects of menthol and nicotine among youth: An examination using e-cigarettes
Krishnan-Sarin S, Green BG, Kong G, Cavallo DA, Jatlow P, Gueorguieva R, Buta E, O’Malley S. Studying the interactive effects of menthol and nicotine among youth: An examination using e-cigarettes. Drug And Alcohol Dependence 2017, 180: 193-199. PMID: 28915478, PMCID: PMC5659733, DOI: 10.1016/j.drugalcdep.2017.07.044.Peer-Reviewed Original ResearchConceptsAd lib useE-cigarettesE-cigarette usersStimulant effectsNicotine concentrationsNicotine-containing e-cigarettesNicotine withdrawal symptomsMenthol concentrationRandom counterbalanced orderPositive rewarding effectsNicotine exposureNicotine withdrawalWithdrawal symptomsRewarding effectsMenthol glucuronideHigh menthol concentrationLow dosesNicotine levelsTobacco productsNicotineCounterbalanced order
2016
Nicotine concentration of e-cigarettes used by adolescents
Morean ME, Kong G, Cavallo DA, Camenga DR, Krishnan-Sarin S. Nicotine concentration of e-cigarettes used by adolescents. Drug And Alcohol Dependence 2016, 167: 224-227. PMID: 27592270, PMCID: PMC5158305, DOI: 10.1016/j.drugalcdep.2016.06.031.Peer-Reviewed Original ResearchConceptsNicotine usersNicotine e-liquidE-cigarettesNicotine concentrationsE-cigarette usersNicotine-free e-liquidsHigher nicotine concentrationsE-liquidsOwn e-cigaretteCross-sectional surveyLiquid nicotine concentrationHigher nicotine levelsE-cigarette use frequencySmoking statusCigarette smokingMale sexMore smokersNicotine exposureTobacco shopsNicotine levelsSmokersAdolescentsMore malesSexMales
2006
Comparison of parental reports of smoking and residential air nicotine concentrations in children
Gehring U, Leaderer B, Heinrich J, Oldenwening M, Giovannangelo M, Nordling E, Merkel G, Hoek G, Bellander T, Brunekreef B. Comparison of parental reports of smoking and residential air nicotine concentrations in children. Occupational And Environmental Medicine 2006, 63: 766. PMID: 16912089, PMCID: PMC2077986, DOI: 10.1136/oem.2006.027151.Peer-Reviewed Original ResearchConceptsAir nicotine concentrationsEnvironmental tobacco smokeUrinary cotinine measurementsNicotine concentrationsETS exposureResidential exposureCotinine measurementsPredictive valueAir nicotine levelsUrinary cotinine levelsUrinary cotinine concentrationsChildren's residential exposureQuestionnaire reportsDose-response fashionResidential ETS exposureNegative predictive valuePositive predictive valueAir nicotineCotinine levelsCotinine concentrationsSymptomatic childrenOccasional smokersSymptom statusTobacco smokeNicotine levels
2000
Using Nicotine Measurements and Parental Reports to Assess Indoor Air: The Piama Birth Cohort Study
Brunekreef B, Leaderer B, van Strien R, Oldenwening M, Smit H, Koopman L, Kerkhof M. Using Nicotine Measurements and Parental Reports to Assess Indoor Air: The Piama Birth Cohort Study. Epidemiology 2000, 11: 350-352. PMID: 10784258, DOI: 10.1097/00001648-200005000-00023.Peer-Reviewed Original ResearchConceptsPIAMA birth cohort studyBirth cohort studyNumber of cigarettesNon-smoking householdsSmoking exposureCohort studySmoking habitsNicotine concentrationsExposure classificationNicotine measurementsMeasurement weeksParental reportsWeeksQuestionnaireQuestionnaire dataSmokingInfantsCigarettesNicotineMonths
1995
Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women
O'Connor T, Holford T, Leaderer B, Hammond S, Bracken M. Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women. American Journal Of Epidemiology 1995, 142: 1315-1321. PMID: 7503052, DOI: 10.1093/oxfordjournals.aje.a117599.Peer-Reviewed Original ResearchConceptsUrine cotinineEnvironmental tobacco smokePregnant womenTobacco smokeWork exposureAir nicotine concentrationsSelf-reported exposurePersonal air monitorsExposure assessment methodsAir nicotineMeasurement of exposureHome exposureCotinineNicotine concentrationsExposure classificationWomenCohen's kappaExposureSpearman rank-order correlation coefficientAir monitorsRank-order correlation coefficientKappaSocial exposureSmokeHigh levels
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