2024
Coverage of Indoor Smoking and Vaping Restrictions in the U.S., 1990–2021
Seidenberg A, Braganza K, Chomas M, Diaz M, Friedman A, Phillips S, Pesko M. Coverage of Indoor Smoking and Vaping Restrictions in the U.S., 1990–2021. American Journal Of Preventive Medicine 2024, 67: 494-502. PMID: 38876294, PMCID: PMC11600437, DOI: 10.1016/j.amepre.2024.06.007.Peer-Reviewed Original ResearchIndoor smoking restrictionsVaping restrictionsAmerican Nonsmokers' Rights FoundationSecondhand smoke exposureTobacco-related diseasesUS Census populationRisk of premature deathE-cigarette useNon-smoking adultsSmoking restrictionsIndoor smokingCensus populationUS populationSmoke exposureE-cigarettesComprehensive restrictionsCoverage of policyPremature deathLocal jurisdictionsPercentage of statesNational coverageE-cigarette aerosolUS statesNational residentsWorkplace
2022
Nicotine dose-dependent epigenomic-wide DNA methylation changes in the mice with long-term electronic cigarette exposure.
Peng G, Xi Y, Bellini C, Pham K, Zhuang ZW, Yan Q, Jia M, Wang G, Lu L, Tang MS, Zhao H, Wang H. Nicotine dose-dependent epigenomic-wide DNA methylation changes in the mice with long-term electronic cigarette exposure. American Journal Of Cancer Research 2022, 12: 3679-3692. PMID: 36119846, PMCID: PMC9442002.Peer-Reviewed Original ResearchElectronic cigarette exposureCigarette exposureMale ApoE-/- miceApoE-/- miceCytokine mRNA expressionPoor health outcomesWhite blood cellsElectronic cigarette useDose-dependent mannerE-cigarette aerosolAerosol inhalationCigarette smokingActivation of MAPKHigher nicotine concentrationsMAPK pathway activationCell-damaging effectsCpG sitesHealth outcomesCigarette useMRNA expressionNicotine concentrationsPathway activationSignificant CpG sitesBlood cellsSignificant alterations
2020
Chemical Adducts of Reactive Flavor Aldehydes Formed in E-Cigarette Liquids Are Cytotoxic and Inhibit Mitochondrial Function in Respiratory Epithelial Cells
Jabba SV, Diaz AN, Erythropel HC, Zimmerman JB, Jordt SE. Chemical Adducts of Reactive Flavor Aldehydes Formed in E-Cigarette Liquids Are Cytotoxic and Inhibit Mitochondrial Function in Respiratory Epithelial Cells. Nicotine & Tobacco Research 2020, 22: s25-s34. PMID: 33320255, PMCID: PMC8224836, DOI: 10.1093/ntr/ntaa185.Peer-Reviewed Original ResearchConceptsRespiratory epithelial cellsBEAS-2B cellsE-cigarette aerosolEpithelial cellsEffect of benzaldehydeE-liquidsMetabolic toxic effectsPrimary human nasal epithelial cellsHuman nasal epithelial cellsInhalation toxicity studiesElectronic nicotine delivery systemsCell metabolic assayNasal epithelial cellsMitochondrial functionAlveolar epithelial cellsE-cigarette liquidsFlavor aldehydesNicotine delivery systemsEnergy metabolic functionsE-cigarette usersEdU cell proliferationConcentration-dependent mannerSpare respiratory capacityInhibits mitochondrial functionLIVE/DEAD cell assay
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