2024
The diagnostic value of the central vein sign in radiologically isolated syndrome
Landes‐Chateau C, Levraut M, Okuda D, Themelin A, Cohen M, Kantarci O, Siva A, Pelletier D, Mondot L, Lebrun‐Frenay C, Lebrun‐Frenay C, Kantarci O, Siva A, Pelletier D, Azevedo C, Makhani N, Okuda D. The diagnostic value of the central vein sign in radiologically isolated syndrome. Annals Of Clinical And Translational Neurology 2024, 11: 662-672. PMID: 38186317, PMCID: PMC10963291, DOI: 10.1002/acn3.51986.Peer-Reviewed Original ResearchConceptsRadiologically isolated syndromeCentral vein signCVS+ lesionsNon-MSMultiple sclerosisControl group of sex-RIS diagnosisAge-matched subjectsDetectable preclinical phaseProportion of lesionsWhite matter lesionsGroup of sex-Effective imaging biomarkerMagnetic resonance imagingDiagnostic performanceDiagnostic accuracyDiagnostic valueLesion criteriaImaging biomarkersLesionsResonance imagingLesion-specificAbsolute numberControl groupROC comparisons
2013
Diagnosing Neuromyelitis Optica
Makhani N, Bigi S, Banwell B, Shroff M. Diagnosing Neuromyelitis Optica. Neuroimaging Clinics Of North America 2013, 23: 279-291. PMID: 23608690, DOI: 10.1016/j.nic.2012.12.007.Peer-Reviewed Original ResearchConceptsNeuromyelitis opticaRecurrent optic neuritisInflammatory demyelinating disorderNMO spectrum disordersChildhood-onset diseaseBroad clinical spectrumAquaporin-4 expressionImportant therapeutic implicationsOptic neuritisTransverse myelitisDemyelinating disorderPrompt diagnosisMagnetic resonance imaging techniquesRecurrent attacksClinical spectrumBrain lesionsHigh riskTherapeutic implicationsAquaporin-4Severe disabilityDiagnostic accuracyOpticaDisordersSpectrum disorderImaging techniques