2024
ASSOCIATIONS BETWEEN REDUCTIONS IN DEPRESSIVE SYMPTOMS AND REDUCTIONS IN PAIN AND ANXIETY SYMPTOMS AND SUBSTANCE USE: EMULATION OF A RANDOMIZED TRIAL
Khan M, Acri M, Ban K, Scheidell J, Stevens E, Manandhar-Sasaki P, Charles D, Chichetto N, Crystal S, Gordan A, Marshall B, Edelman E, Justice A, Braithwaite R, Caniglia E. ASSOCIATIONS BETWEEN REDUCTIONS IN DEPRESSIVE SYMPTOMS AND REDUCTIONS IN PAIN AND ANXIETY SYMPTOMS AND SUBSTANCE USE: EMULATION OF A RANDOMIZED TRIAL. AJPM Focus 2024, 100258. DOI: 10.1016/j.focus.2024.100258.Peer-Reviewed Original ResearchUnhealthy alcohol useDepressive symptomsAnxiety symptomsIllicit opioid useOdds ratioAlcohol useVeterans Aging Cohort StudyPain symptomsConfidence intervalsTarget trial emulation frameworkElevated depressive symptomsAssociated with reductionsReducing depressive symptomsAging Cohort StudySubstance useOpioid useMultisite observational studyDepressive symptom reductionNext follow-up visitUS veteransReduce painFollow-up visitCohort studyAntidepressant medicationComparing individuals
2023
The Association of Prescribed Opioids and Incident Cardiovascular Disease
Sung M, Eden S, Becker W, Crystal S, Duncan M, Gordon K, Kerns R, Kundu S, Freiberg M, So-Armah K, Edelman E. The Association of Prescribed Opioids and Incident Cardiovascular Disease. Journal Of Pain 2023, 25: 104436. PMID: 38029949, PMCID: PMC11058015, DOI: 10.1016/j.jpain.2023.11.019.Peer-Reviewed Original ResearchIncident cardiovascular diseaseModifiable CVD risk factorsCVD risk factorsHuman immunodeficiency virusCardiovascular diseasePrescribed opioidsOpioid receiptRisk factorsUse disordersCox proportional hazards regression modelVeterans Aging Cohort StudyVeterans Health Administration (VHA) carePropensity scoreProportional hazards regression modelsCVD incidence ratesPrescription opioid exposureIncident CVD eventsPrevalence of hypertensionAging Cohort StudyHigher opioid dosesOpioid use disorderHazards regression modelsNational prospective cohortVeterans Administration dataCocaine use disorder