2018
Deuterium metabolic imaging (DMI) for MRI-based 3D mapping of metabolism in vivo
De Feyter HM, Behar KL, Corbin ZA, Fulbright RK, Brown PB, McIntyre S, Nixon TW, Rothman DL, de Graaf RA. Deuterium metabolic imaging (DMI) for MRI-based 3D mapping of metabolism in vivo. Science Advances 2018, 4: eaat7314. PMID: 30140744, PMCID: PMC6105304, DOI: 10.1126/sciadv.aat7314.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainBrain MappingCase-Control StudiesDeuteriumGliomaGlucoseHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedRatsRats, Inbred F344ConceptsOral intakeMetabolic imagingGlucose uptakeHigh-grade brain tumorsRat glioma modelPositron emission tomography (PET) detectionSimilar metabolic patternMetabolic imaging techniquesDeuterium metabolic imagingHigher glucose uptakeGlucose analog 2FDG-PETF-fluoroIntravenous infusionBrain tumorsGlioma modelGlucose metabolismNormal brainTomography detectionAnimal modelsMagnetic resonance spectroscopicTumor tissueHuman liverMetabolic patternsNoninvasive approach
2016
Detection of cerebral NAD+ in humans at 7T
de Graaf R, De Feyter H, Brown PB, Nixon TW, Rothman DL, Behar KL. Detection of cerebral NAD+ in humans at 7T. Magnetic Resonance In Medicine 2016, 78: 828-835. PMID: 27670385, PMCID: PMC5366282, DOI: 10.1002/mrm.26465.Peer-Reviewed Original ResearchAdultAlgorithmsBrainBrain ChemistryFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNADSignal Processing, Computer-Assisted