2024
Differential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations
Hua L, Solomon A, Tenembaum S, Scalfari A, Rovira À, Rostasy K, Newsome S, Marrie R, Magyari M, Kantarci O, Hemmer B, Hemingway C, Harnegie M, Graves J, Cohen J, Bove R, Banwell B, Corboy J, Waubant E. Differential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations. JAMA Neurology 2024, 81 PMID: 39283621, DOI: 10.1001/jamaneurol.2024.3062.Peer-Reviewed Original ResearchMisdiagnosis and underdiagnosis of multiple sclerosis: A systematic review and meta-analysis.
Zürrer W, Cannon A, Ilchenko D, Gaitán M, Granberg T, Piehl F, Solomon A, Ineichen B. Misdiagnosis and underdiagnosis of multiple sclerosis: A systematic review and meta-analysis. Multiple Sclerosis Journal 2024, 13524585241274527. PMID: 39246018, DOI: 10.1177/13524585241274527.Peer-Reviewed Original ResearchMeta-analysisSystematic reviewPooled proportionDiagnostic errorsPotential impact of sexMultiple sclerosisMS careMS misdiagnosisHealthcare systemQualitative synthesisImpact patientsMeta-analysesMS diagnosisHighest prevalenceImpact of sexDiagnostic delayUnderdiagnosisFrequency of misdiagnosisDiagnostic challengeMisdiagnosisCareHealthcarePatientsDiagnosisPotential impactMisdiagnosis of Multiple Sclerosis: Past, Present, and Future
Rjeily N, Solomon A. Misdiagnosis of Multiple Sclerosis: Past, Present, and Future. Current Neurology And Neuroscience Reports 2024, 1-11. PMID: 39243340, DOI: 10.1007/s11910-024-01371-w.Peer-Reviewed Original ResearchMS diagnostic criteriaMultiple sclerosisDiagnostic criteriaCentral vein signParamagnetic rim lesionsAssociated with misdiagnosisRecent FindingsRecent studiesMS misdiagnosisMRI findingsEvaluating patientsSuspected MSDiagnostic accuracyRim lesionsFindingsRecent studiesImaging biomarkersMisdiagnosisDiagnostic biomarkersCommon disordersPatientsBiomarkersPotential strategyMultiple sclerosis presenting with paroxysmal symptoms: Patients at the limitations of current diagnostic criteria.
Heward K, Roy-Hewitson C, Solomon A. Multiple sclerosis presenting with paroxysmal symptoms: Patients at the limitations of current diagnostic criteria. Multiple Sclerosis Journal 2024, 13524585241253513. PMID: 38751226, DOI: 10.1177/13524585241253513.Peer-Reviewed Original ResearchMS diagnostic criteriaCentral nervous systemMultiple sclerosisDiagnostic criteriaClinically isolated syndromeRelapsing remitting MSParoxysmal neurological symptomsLhermitte's phenomenonOptic neuritisClinical attacksTrigeminal neuralgiaCase seriesNeurological symptomsTonic spasmsPatient presentationParoxysmal symptomsPatientsClinical guidanceNervous systemSyndromeOptimal careSymptomsAnecdotal reportsSclerosisNeuralgiaChoroid plexus volume differentiates MS from its mimics
Levit E, Ren Z, Gonzenbach V, Azevedo C, Calabresi P, Cree B, Freeman L, Longbrake E, Oh J, Schindler M, Sicotte N, Reich D, Ontaneda D, Sati P, Cao Q, Shinohara R, Solomon A. Choroid plexus volume differentiates MS from its mimics. Multiple Sclerosis Journal 2024, 30: 1072-1076. PMID: 38481081, PMCID: PMC11288781, DOI: 10.1177/13524585241238094.Peer-Reviewed Original ResearchMultiple Sclerosis Diagnostic Delay and Misdiagnosis
Kaisey M, Solomon A. Multiple Sclerosis Diagnostic Delay and Misdiagnosis. Neurologic Clinics 2024, 42: 1-13. PMID: 37980109, DOI: 10.1016/j.ncl.2023.07.001.Peer-Reviewed Original ResearchConceptsMultiple sclerosis misdiagnosisPatients' clinical outcomesMS diagnostic criteriaMS symptomsClinical outcomesDiagnostic delayDiagnostic challengeDiagnostic criteriaMS misdiagnosisDiagnostic biomarkersAccurate diagnosisIncorrect diagnosisPatientsDiagnosisMisdiagnosisEducational effortsSymptoms
2023
A multicenter pilot study evaluating simplified central vein assessment for the diagnosis of multiple sclerosis
Daboul L, O’Donnell C, Amin M, Rodrigues P, Derbyshire J, Azevedo C, Bar-Or A, Caverzasi E, Calabresi P, Cree B, Freeman L, Henry R, Longbrake E, Oh J, Papinutto N, Pelletier D, Prchkovska V, Raza P, Ramos M, Samudralwar R, Schindler M, Sotirchos E, Sicotte N, Solomon A, Shinohara R, Reich D, Sati P, Ontaneda D. A multicenter pilot study evaluating simplified central vein assessment for the diagnosis of multiple sclerosis. Multiple Sclerosis Journal 2023, 30: 25-34. PMID: 38088067, PMCID: PMC11037932, DOI: 10.1177/13524585231214360.Peer-Reviewed Original ResearchConceptsCentral vein signMultiple sclerosisPositive lesionsInter-rater agreementDiagnosis of MSMagnetic resonance imaging (MRI) biomarkersDiagnostic performancePossible multiple sclerosisInter-rater reliability assessmentGood diagnostic performanceMcDonald criteriaMulticenter studyVein assessmentMean ageVein signImaging biomarkersLesionsMRI sequencesCharacteristic curveSclerosisPatientsDiagnosisAssessmentParticipantsOptimal method
2020
Effects of Disease Modifying Therapy (DMT) Exposure on infant birth weight and birth length: Interim Data from Prospective PREG-MS Cohort. (4481)
Pol-Patil J, Maneiri M, Mahlanza T, Klawiter E, Solomon A, Lathi E, Ionete C, Morales I, Severson C, Stankiewicz J, Cabot A, Katz J, Sadovnick A, Chaves C, Bhattacharyya S, Kimbrough D, Baber U, Beretich B, Rizvi S, Napoli S, Chitnis T, Singhal T, Kaplan T, Houtchens M. Effects of Disease Modifying Therapy (DMT) Exposure on infant birth weight and birth length: Interim Data from Prospective PREG-MS Cohort. (4481). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4481.Peer-Reviewed Original Research
2019
Challenges in Multiple Sclerosis Diagnosis: Misapplication and Misunderstanding of the McDonald Criteria (S6.001)
Solomon A, Pettigrew R, Naismith R, Chahin S, Krieger S, Weinshenker B. Challenges in Multiple Sclerosis Diagnosis: Misapplication and Misunderstanding of the McDonald Criteria (S6.001). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.s6.001.Peer-Reviewed Original Research
2016
The spectrum of multiple sclerosis misdiagnosis in the era of McDonald criteria: A multicenter study (PL01.003)
Solomon A, Bourdette D, Cross A, Applebee A, Skidd P, Howard D, Spain R, Cameron M, Kim E, Mass M, Yadav V, Whitham R, Longbrake E, Naismith R, Wu G, Parks B, Wingerchuk D, Rabin B, Toledano M, Tobin W, Kantarci O, Carter J, Keegan B, Weinshenker B. The spectrum of multiple sclerosis misdiagnosis in the era of McDonald criteria: A multicenter study (PL01.003). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.pl01.003.Peer-Reviewed Original ResearchComparison of Therapeutic Goals and Preferences in Multiple Sclerosis Patients and Providers Using Nominal Group Technique (P3.100)
Col N, Solomon A, Qu H, Springmann V, Ionete C, Pbert L, Anthony W, Griffin C, Tierman B, Kutz C, Berrios Morales I, Hopson A, Phillips G, Alvarez E. Comparison of Therapeutic Goals and Preferences in Multiple Sclerosis Patients and Providers Using Nominal Group Technique (P3.100). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.p3.100.Peer-Reviewed Original Research
2014
Multiple Cranial Neuropathy in Paraneoplastic Anti-Hu Antibody Syndrome (P4.029)
Schmidt T, Solomon A. Multiple Cranial Neuropathy in Paraneoplastic Anti-Hu Antibody Syndrome (P4.029). Neurology 2014, 82 DOI: 10.1212/wnl.82.10_supplement.p4.029.Peer-Reviewed Original Research