2005
A family study of early‐onset obsessive‐compulsive disorder
do Rosario‐Campos M, Leckman JF, Curi M, Quatrano S, Katsovitch L, Miguel EC, Pauls DL. A family study of early‐onset obsessive‐compulsive disorder. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2005, 136B: 92-97. PMID: 15892140, DOI: 10.1002/ajmg.b.30149.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderRecurrence riskChronic ticsFirst-degree family membersChildhood-onset obsessive-compulsive disorderDiagnosis of OCDChronic tic disorderStandardized semi-structured interviewFirst-degree relativesEarly-onset casesOnset obsessive-compulsive disorderDSM-IV criteriaEarly-onset obsessive-compulsive disorderBest-estimate processRandom digit dialingHigh comorbid ratesAge of onsetFamily studiesHigh genetic loadingMean ageSpecialty clinicTic disordersComorbid ratesValid subgroupsCase relatives
2002
Characteristics of acute stress symptoms and nitric oxide concentration in young rescue workers in Taiwan
Yeh CB, Leckman J, Wan FJ, Shiah IS, Lu RB. Characteristics of acute stress symptoms and nitric oxide concentration in young rescue workers in Taiwan. Psychiatry Research 2002, 112: 59-68. PMID: 12379451, DOI: 10.1016/s0165-1781(02)00179-8.Peer-Reviewed Original ResearchConceptsAcute stress disorderYoung military personnelControl groupMale military personnelNitric oxideInitial evaluationMilitary personnelPoint prevalence ratesAcute stress symptomsDSM-IV criteriaSignificant inverse correlationStress symptomsNitric oxide concentrationPlasma concentrationsPlasma measuresPrevalence ratesRelated syndromesNeuropsychological interviewStress disorderInverse correlationPlasma samplesLongitudinal studyPotential roleRescue workersDisaster workers