https://medicine.yale.edu/lab/spudich/news-rss/?title=Latest%20News&orgId=120156 A selection of the latest research, academic, and other newsworthy developments at Spudich Lab en-us Copyright 2026 Yale School of Medicine Thu, 12 Mar 2026 17:42:00 Z https://medicine.yale.edu/lab/spudich/news-article/nimh-grant-advances-research-into-long-covid-and-related-brain-changes/ https://medicine.yale.edu/lab/spudich/news-article/nimh-grant-advances-research-into-long-covid-and-related-brain-changes/ The National Institute of Mental Health (NIMH) has awarded a five-year R01 grant to Serena Spudich, MD, MA, Gilbert H. Glaser Professor of Neurology; Todd Constable, PhD, Elizabeth Mears and House Jameson Professor of Radiology; and Lindsay McAlpine, MD, assistant professor of neurology for research that will employ the use of novel neuroimaging to understand the brain changes that occur alongside the neurologic symptoms of Long COVID. Mon, 24 Feb 2025 05:00:00 Z https://medicine.yale.edu/lab/spudich/news-article/new-evidence-supports-autoimmunity-as-one-of-long-covids-underlying-drivers/ https://medicine.yale.edu/lab/spudich/news-article/new-evidence-supports-autoimmunity-as-one-of-long-covids-underlying-drivers/ Mice that received antibodies from Long COVID patients showed symptoms including pain and dizziness, a Yale-led study has found. Mon, 22 Jul 2024 16:00:00 Z https://www.webmd.com/covid/news/20240718/depression-or-long-covid-understanding-overlapping-symptoms https://www.webmd.com/covid/news/20240718/depression-or-long-covid-understanding-overlapping-symptoms The list of long COVID symptoms has reached the hundreds, making it especially difficult for doctors to parse through each patient’s health profiles to determine what is coming from long COVID and how to treat it. Thu, 18 Jul 2024 04:00:00 Z https://medicine.yale.edu/lab/spudich/news-article/mcalpine-wins-grant-to-elucidate-causes-of-neuro-pasc/ https://medicine.yale.edu/lab/spudich/news-article/mcalpine-wins-grant-to-elucidate-causes-of-neuro-pasc/ Assistant Professor of Neurology Lindsay McAlpine, MD, has received the Mentored Patient-Oriented Research Career Development Award from the National Institute of Neurological Disorders and Stroke (NINDS). The grant will provide mentorship as McAlpine continues research on the causes of neurologic post-acute sequelae of SARS-CoV-2 infection (neuro-PASC). Mon, 08 Jul 2024 04:00:00 Z https://www.youtube.com/watch?v=L053vXI1g8I https://www.youtube.com/watch?v=L053vXI1g8I Lindsay McAlpine, MD, delivers a lecture, "Neuropathogenesis of Long COVID," as part of the Demystifying Long COVID North American Conference 2024, where she details her research in this field and her work within the COVID Mind Study at Yale. Mon, 01 Jul 2024 04:00:00 Z https://www.yalemedicine.org/news/how-to-manage-long-covid-brain-fog https://www.yalemedicine.org/news/how-to-manage-long-covid-brain-fog Yale Medicine doctors discuss “brain fog” and how it can affect people with Long COVID. It’s not curable, but treatments and coping strategies can help. Wed, 29 May 2024 04:00:00 Z https://www.self.com/story/signs-of-autoimmune-disease https://www.self.com/story/signs-of-autoimmune-disease Most autoimmune diseases are chronic conditions, meaning they don’t have a cure. However, they are usually very treatable; an effective medication plan, physical therapy, and certain surgical procedures can help slow down or prevent severe complications or even permanent damage down the road. That’s why seeing a doctor about your symptoms early on is so important. Here are six signs you might have an autoimmune disease. Fri, 17 May 2024 04:00:00 Z https://www.youtube.com/watch?v=9g11r3Z3fi4 https://www.youtube.com/watch?v=9g11r3Z3fi4 Assistant Professor Lindsay McAlpine, MD, delivered a research lecture, "Vascular Inflammation in Neuropsychiatric Post-Acute Sequelae of COVID-19," as part of the Demystifying Long COVID International Conference 2023. Mon, 08 Jan 2024 05:00:00 Z https://www.youtube.com/watch?v=X-HxwX4o71E https://www.youtube.com/watch?v=X-HxwX4o71E Assistant Professor Lindsay McAlpine, MD, delivers a research lecture, "Focal Cerebral Hypoperfusion in Individuals with Cognitive Impairment After COVID-19," as part of the Demystifying Long COVID International Conference 2023. Mon, 08 Jan 2024 05:00:00 Z https://medicine.yale.edu/lab/spudich/news-article/brain-fog-new-study-examines-causes-of-this-long-covid-symptom/ https://medicine.yale.edu/lab/spudich/news-article/brain-fog-new-study-examines-causes-of-this-long-covid-symptom/ A new study finds that neuroinflammation and blood-brain-barrier dysfunction are not likely drivers of the neuropsychiatric symptoms of Long COVID, giving researchers more clues in their quest to uncover what actually may be the culprit. This study is the first time researchers have tested a large cohort of people living with Long COVID for spinal fluid markers of brain inflammation and blood-brain-barrier dysfunction. Fri, 10 Nov 2023 16:00:00 Z https://www.yalemedicine.org/news/long-covid-symptoms https://www.yalemedicine.org/news/long-covid-symptoms Yale’s Long COVID program aims to treat patients with lingering COVID-19 symptoms, such as fatigue, brain fog, and shortness of breath. Fri, 27 Oct 2023 04:00:00 Z https://www.youtube.com/watch?v=NAz7s2LriA4 https://www.youtube.com/watch?v=NAz7s2LriA4 As a follow-up to a similar QA webinar held in July 2023, Assistant Professor Lindsay McAlpine, MD, shares additional research and clinical insights into the persistent neurologic symptoms of Long COVID. Wed, 13 Sep 2023 04:00:00 Z https://www.youtube.com/watch?v=XjmLjgZGBRA https://www.youtube.com/watch?v=XjmLjgZGBRA Assistant Professor Lindsay McAlpine, MD, details her work with Long COVID patients in the NeuroCOVID Clinic at Yale, as well as the latest research and treatment methods targeting persistent neurologic symptoms of COVID-19. Wed, 02 Aug 2023 04:00:00 Z https://medicine.yale.edu/lab/spudich/news-article/center-for-brain-and-mind-health-first-annual-symposium/ https://medicine.yale.edu/lab/spudich/news-article/center-for-brain-and-mind-health-first-annual-symposium/ The CBMH first annual symposium was held in May 2023, with over 100 in-person participants ranging from trainees to senior faculty. Thu, 01 Jun 2023 04:00:00 Z https://medicine.yale.edu/lab/spudich/news-article/yale-creates-center-devoted-to-brain-and-mind-health/ https://medicine.yale.edu/lab/spudich/news-article/yale-creates-center-devoted-to-brain-and-mind-health/ The center will foster transformational work that bridges existing departments, levels of analysis, and disciplinary boundaries, and will focus on areas of clinical and translational neuroscience that are broader than any single disease. Tue, 30 Aug 2022 04:00:00 Z