New Strategies Needed for TKI Resistance in EGFR+ Lung Cancer
The development of tyrosine kinase inhibitors (TKIs) has revolutionized the treatment of EGFR-mutant non–small cell lung cancer (NSCLC) in recent years, but new strategies are needed to overcome resistance mechanisms that promote disease recurrence, Katerina A. Politi, PhD, said during a 2019 ASCO session featuring emerging research.Source: OncLive
Lung Cancer Research Foundation Announces New Scientific Advisory Board Chair
NEW YORK, May 23, 2019 /PRNewswire/ -- The Lung Cancer Research Foundation (LCRF) today announced that Dr. Katerina Politi has been named the chair of its Scientific Advisory Board. Politi, an Associate Professor of Pathology and Internal Medicine (in the Section of Medical Oncology) at Yale School of Medicine, will be taking over the role from Dr. James B. Dougherty, who has held the chair position for 14 years.Source: Yahoo! Finance
Yale Cancer Center Scientists Receive Grant to Advance Lung Cancer Research
Katerina Politi, PhD and Don Nguyen, PhD, members of the Signal Transduction Research Program at Yale Cancer Center (YCC), have received a 5-year, nearly $4 million National Cancer Institute (NCI) grant to support Lung Cancer research.
Yale researchers uncover lung cancer resistance mechanism
A new Yale study has shown how lung cancer may develop resistance to therapy in some patients. Researchers at the School of Medicine have found that lung cancer cells may become resistant to a type of cancer therapy by disrupting patients’ normal immune response. The finding provides researchers with a molecular basis for understanding drug resistance in lung cancer. The study was published in the Cancer Discovery journal on Oct. 12. “Understanding the biology of acquired resistance to these therapies is really important because this knowledge will allow us to figure out what we need to do to treat resistant tumors,” said Katerina Politi, a professor in the School of Medicine’s Department of Pathology and the study’s senior author. “Knowledge of how tumors escape can also help us develop ideas for therapeutic approaches to prevent drug resistance.”Source: Yale Daily News
‘Running Sprints During A Marathon’: Experts Say Mental Health Suffering As COVID Rages On
“It’s hard, because we had these expectations that things were getting better and now they’re getting worse,” said Dr. Peter Morgan, chair of psychiatry at Bridgeport hospital and associate professor of psychiatry at the Yale University School of Medicine.Source: Connecticut Post
Cannabis and Psychosis: Recent Epidemiological Findings Continuing the “Causality Debate”
In a new piece published in The American Journal of Psychiatry, Suhas Ganeesh, MD, postdoctoral associate in psychiatry, and Deepak Cyril D'Souza, MD, professor of psychiatry at Yale School of Medicine, argue that if cannabis caused psychosis, then the increases in the rates of cannabis use should be accompanied by a parallel increase in the rates of psychosis.Source: The American Journal of Psychiatry
Nikayin, Ostroff: Advanced Training in Interventional Psychiatry
Sina Nikayin, MD, assistant professor of psychiatry, and Robert Ostroff, MD, co-medical director of the Interventional Psychiatry Service at Yale New Haven Psychiatric Hospital, are co-authors of a paper in Journal of the Neurological Sciences that describes interventional psychiatry training at Yale New Haven Psychiatric Hospital.Source: Journal of the Neurological Sciences
For those battling mental illness, cards deliver hope during the holidays
In 2019, Katherine Ponte, JD, MBA, lecturer in the Department of Psychiatry, created a program called Psych Ward Greeting Cards to bring hope and comfort — via greeting cards with inspirational messages and sometimes small gifts — to hospitalized patients in psychiatric wards. Through the program, people donate store-bought or handmade greeting cards to Ponte in which they write notes of encouragement or messages of hope for recovery.Source: Yale News
Nasal Vaccination May Protect Against Respiratory Viruses Better Than Injected Vaccines
Akiko Iwasaki, PhD, discusses her lab's finding that intranasal vaccinations, by triggering immune properties of mucosal membranes, may offer better protection against respiratory viruses than injected vaccines.
Nasal Vaccine May Aid Fight Against New Viral Variants
Akiko Iwasaki and her colleagues found that intranasal vaccination provided broad-based protection against heterologous respiratory viruses in mice, while so-called systemic immunization, which uses an injection to elicit body-wide protection, did not.Source: YaleNews
Would You Pay Someone to Listen to You Vent? The Rise of 'Professional Listeners'
Sofia Noori, MD, MPH, clinical instructor in psychiatry, spoke to Salon for a story about the growing industry of professional listeners. She said there is an ethical gray area when wellness services and mental health services are mistaken for each other.Source: Salon
Solomon: My Book Was Censored in China. Now It’s Blacklisted — in Texas.
"Finding my work thus blacklisted disturbingly evoked a childhood during which I was shunned and abused for being gay, in which I felt ashamed, defenseless, sad and epically vulnerable," writes Andrew Solomon, PhD, Lecturer in the Department of Psychiatry at Yale School of Medicine in a new essay for The New York Times.Source: The New York Times