New Strategies Needed for TKI Resistance in EGFR+ Lung Cancer
The development of tyrosine kinase inhibitors (TKIs) has revolutionized the treatment of EGFR-mutant non–small cell lung cancer (NSCLC) in recent years, but new strategies are needed to overcome resistance mechanisms that promote disease recurrence, Katerina A. Politi, PhD, said during a 2019 ASCO session featuring emerging research.Source: OncLive
Lung Cancer Research Foundation Announces New Scientific Advisory Board Chair
NEW YORK, May 23, 2019 /PRNewswire/ -- The Lung Cancer Research Foundation (LCRF) today announced that Dr. Katerina Politi has been named the chair of its Scientific Advisory Board. Politi, an Associate Professor of Pathology and Internal Medicine (in the Section of Medical Oncology) at Yale School of Medicine, will be taking over the role from Dr. James B. Dougherty, who has held the chair position for 14 years.Source: Yahoo! Finance
Yale Cancer Center Scientists Receive Grant to Advance Lung Cancer Research
Katerina Politi, PhD and Don Nguyen, PhD, members of the Signal Transduction Research Program at Yale Cancer Center (YCC), have received a 5-year, nearly $4 million National Cancer Institute (NCI) grant to support Lung Cancer research.
Yale researchers uncover lung cancer resistance mechanism
A new Yale study has shown how lung cancer may develop resistance to therapy in some patients. Researchers at the School of Medicine have found that lung cancer cells may become resistant to a type of cancer therapy by disrupting patients’ normal immune response. The finding provides researchers with a molecular basis for understanding drug resistance in lung cancer. The study was published in the Cancer Discovery journal on Oct. 12. “Understanding the biology of acquired resistance to these therapies is really important because this knowledge will allow us to figure out what we need to do to treat resistant tumors,” said Katerina Politi, a professor in the School of Medicine’s Department of Pathology and the study’s senior author. “Knowledge of how tumors escape can also help us develop ideas for therapeutic approaches to prevent drug resistance.”Source: Yale Daily News
Sinha Elected Vice President; Mason on Board of Research Society on Alcohol
Rajita Sinha, PhD, Foundations Fund Professor of Psychiatry and professor in the Child Study Center and of neuroscience; and Graeme Mason, PhD, professor of radiology and biomedical imaging and of psychiatry, have been elected to officer and board positions for the Research Society on Alcohol (RSA).
Student Loan Forgiveness Is a Racial Justice Issue. The Senate Is Wrong to Overturn Biden's Plan
"Student debt after all is a racial justice issue. Due to systemic racism, Black and brown Americans have to borrow more money to achieve the same level of education. And even after achieving that same level of education, we are subjected to workplace inequities rendering us as statistically more likely to be underpaid, under-promoted, and undervalued no matter our field of employ," writes Carmen Black, MD, assistant professor of psychiatry and director of Social Justice and Health Equity (SJHE) Education.Source: Newsweek
Preliminary Study of Interactive Effects of THC and Ethanol on Driving
Yale researchers, in a paper published in Psychopharmacology, studied the combined and separate effects of ethanol and tetrahydrocannabinol (THC) on perceived ability to drive, subjective effects, and simulated driving.Source: Psychopharmacology
Crusto Honored by Society for Community Research and Action
Cindy A. Crusto, PhD, professor of psychiatry (psychology) and associate dean for gender equity at Yale School of Medicine, has been chosen to receive the 2022 Outstanding Contributions for Mentorship in Racial Justice Award from the Society for Community Research and Action (SCRA), Division 27 of the American Psychological Association.
D'Souza Edits 'Marijuana and Madness'
Deepak Cyril D’Souza, MD, Albert E. Kent Professor of Psychiatry and a leading expert on the pharmacology of cannabinoids, is editor of “Marijuana and Madness,” the third edition of an award-winning book that provides a comprehensive overview of the complex associations between cannabis and mental illness.
Lived Experience–Led Research Agenda to Address Early Death in People With a Diagnosis of a Serious Mental Illness
Greg Rhee, PhD, assistant professor adjunct of psychiatry, is co-author of a paper in JAMA Network Open that attempts to develop the first lived experience–led research agenda to address early mortality in people with serious mental illness.Source: JAMA Network Open
Kathy Carroll Honored with New Playground in Newhallville
A brand new, vibrant playground in the Newhallville section of New Haven stands as a lasting monument to the legacy of Kathleen “Kathy” Carroll, PhD, grounded in Carroll’s love of community, passion for citizenship and inclusion, and dedication to giving.
Considerations of Sex and Gender in FDA Tobacco Regulation
Danielle R. Davis, PhD, assistant professor of psychiatry; Suchitra Krishnan-Sarin, PhD, Albert E. Kent Professor of Psychiatry; and Carolyn M. Mazure, PhD, Norma Weinberg Spungen and Joan Lebson Bildner Professor in Women's Health Research and Professor of Psychiatry and of Psychology, and director, Women's Health Research at Yale, provide examples of proposed regulatory changes by the FDA that could benefit from a greater focus on women and the influence of sex and gender on tobacco use.Source: JAMA
Strategies for the Management of Voices Shared in a Brazilian Hearing Voices Group
Graziela Reis, MPH; Larry Davidson, PhD; Chyrell Bellamy, PhD, and Mark Costa, MD, are co-authors of a paper in Psychiatric Quarterly that describes the voice management strategies shared in a hearing voices peer support group within a Brazilian public mental health service.Source: Psychiatric Quarterly
Desai Launches New Field of Structural Psychology
The academic and generational experiences of Miraj U. Desai, PhD, assistant professor of psychiatry, have come together in the Structural Health and Psychology (SHP) Lab, where Desai investigates the structural bases of health, equity, and inequity, as well as in a new field Desai created, called structural psychology. Structural psychology spans the entire translational science spectrum, inclusive of basic, clinical, community, and population health research.