2010
Role of metallothionein in cadmium traffic and toxicity in kidneys and other mammalian organs
Sabolić I, Breljak D, Škarica M, Herak-Kramberger C. Role of metallothionein in cadmium traffic and toxicity in kidneys and other mammalian organs. BioMetals 2010, 23: 897-926. PMID: 20549307, DOI: 10.1007/s10534-010-9351-z.Peer-Reviewed Original ResearchConceptsProximal tubule cellsChronic toxicityTubular injuryRole of metallothioneinMT-1Intracellular MTSquamous epitheliumCytotoxicity of CdChronic intoxicationTubule cellsVariety of stimuliRole of MTKidneyMajor physiological functionsMT-2Oxidative stressAdult mammalsMT-4Acute toxicityMajor targetMT-3Essential metals ZnMost tissuesToxicityDe novo synthesis
2005
Rat renal glucose transporter SGLT1 exhibits zonal distribution and androgen-dependent gender differences
Sabolić I, Škarica M, Gorboulev V, Ljubojević M, Balen D, Herak-Kramberger C, Koepsell H. Rat renal glucose transporter SGLT1 exhibits zonal distribution and androgen-dependent gender differences. American Journal Of Physiology. Renal Physiology 2005, 290: f913-f926. PMID: 16204409, DOI: 10.1152/ajprenal.00270.2005.Peer-Reviewed Original ResearchConceptsBrush border membraneProximal tubulesPT segmentsRat SGLT1Gender differencesExpression of SGLT1Androgen inhibitionRenal capsuleSmooth musclePeptide-specific polyclonal antibodiesRat kidneyGlucose transporter SGLT1S3 segmentBlood vesselsPart of glucoseImmunoblotting dataMRNA levelsMammalian proximal tubuleMedullary raysBBM vesiclesTissue cryosectionsTransporter SGLT1KidneySGLT1Immunostaining