Within tarantula venom, new hope for safe and novel painkillers found
Screening more than 100 spider toxins, Yale researchers identified a protein from the venom of the Peruvian green velvet tarantula that blunts activity in pain-transmitting neurons. The findings, reported in the March 3 issue of the journal Current Biology, show the new screening method used by the scientists has the potential to search millions of different spider toxins for safe pain-killing drugs and therapies.
Our recent TRPA1 toxineering paper, led by Junhong Gui, has been covered by the New York Times.
"Toxineering," a new method developed by investigators at the Kavli Institute for Neuroscience at Yale, may be used to screen millions of spider toxins for safe pain-killing drugs and therapies. With it, Michael Nitabach and his colleagues have identified a protein from the venom of the Peruvian green velvet tarantula that targets an ion channel linked to neuropathic pain.Source: The New York Times
Lighting a new path to understanding the 'language' of the brain
School of Medicine researchers have developed a new technique that allows them to non-invasively and simultaneously measure electrical activity in many neurons in a living organism, a prerequisite for understanding the complex language of the brain. The technique, described in the Aug. 8 issue of the journal Cell, involves inserting a fluorescent protein that varies in intensity in response to changes in electrical signals into neurons and recording the changing light with optical sensors.
Grant Will Help Yale Team Develop Diagnostic Tool to Evaluate Tumors
The Yale Center for Clinical Investigation (YCCI) has awarded a research pilot award to an interdisciplinary team of Yale researchers for a project titled, “Utilizing Machine Learning to Model the Volumetric Growth of Vestibular Schwannomas.”
Study: Alzheimer's Drug Shows Modest Success Slowing Declines in Memory, Thinking
Christopher Van Dyck, MD, professor of psychiatry and director of the Alzheimer's Disease Research Unit, spoke about an experimental drug for Alzheimer's disease patients at the Clinical Trials on Alzheimer's Disease meeting in San Francisco in November.Source: NPR
Provision of Mental Health Services in the Veterans Health Administration: A Nationwide Comparison With Other Providers
On average, Veterans Health Administration (VHA) mental healthcare facilities offer significantly more treatment modalities, specialized services, and dedicated treatment programs than non-VHA facilities, according to a new study by Yale Psychiatry researchers published online in Psychiatric Services.
Yale Study Seeks to Understand Neurobiology Underlying Bipolar Disorder Vs. Major Depressive Disorder
Yale scientists, including Sophie Holmes, PhD; Ruth Asch, PhD; and Irina Esterlis, PhD, used positron emission tomography to understand the neurobiology underlying bipolar disorder versus major depressive disorder. The findings were published in Biological Psychiatry.Source: Biological Psychiatry
Cook, Simiola Awarded PCORI Grant
Joan Cook, PhD, professor of psychiatry, and Vanessa Simiola, research assistant, have been awarded a Patient-Centered Outcomes Research Institute grant to implement written exposure therapy for posttraumatic stress disorder in six civilian health care systems across the United States.Source: Patient-Centered Outcomes Research Institute
Federal Grant Will Fund PRCH's 'Recovery Finance' Project
Researchers from the Yale Department of Psychiatry’s Program for Recovery and Community Health (PRCH), including Annie Harper, PhD, associate research scientist in psychiatry; and Chyrell Bellamy, PhD, professor of psychiatry and director of PRCH, have been awarded a $1.675 million grant by the National Institute On Minority Health And Health Disparities of the National Institutes of Health.
Collaboration on NIH grant between Sullivan, Nez Henderson will create program to help Indigenous women experiencing domestic violence quit smoking
Tami Sullivan, PhD, associate professor of psychiatry at Yale School of Medicine, and Patricia Nez Henderson, MD, MPH, vice president for the Black Hills Center for American Indian Health (BHCAIH) and the first Indigenous woman to graduate from Yale School of Medicine, have been awarded a grant from the National Institutes of Health (NIH) to pilot a mindfulness-based, culturally-tailored smoking cessation intervention for Indigenous women who experience intimate partner violence (IPV).
Yuen's CHATogether program helps AAPI families broach difficult topics, according to a new study
A new study evaluating the therapeutic impacts of CHATogether suggest that through its methods of storytelling and creative digital theater, the CHATogether program facilitates the discussion of challenging topics specific to the AAPI community such as mental health, racial identity development, and challenges on child-parent relational conflicts.
Physician-Legislators in Federal and State Government in 2022
Tanvee Varma, a third-year student at Yale School of Medicine, and Matthew Goldenberg, MD, MSc, associate professor of psychiatry, are co-authors of a paper in JAMA that reports on the number of physicians who hold public office.Source: JAMA
Does Street Outreach Engage Its Intended Target Population? Clinical Experience in the Veteran’s Health Administration Homeless Service Programs
Emma Lo, MD; Jack Tsai, PhD; Elina Stefanovics, PhD; and Robert Rosenheck, MD, are co-authors of a paper in Psychiatric Quarterly that found veterans engaged through clinical street outreach programs reported substantially more days of unsheltered homelessness than a clinic-referred group of veterans.Source: Psychiatric Quarterly
Verplaetse Presents to NIDA and NIAAA
Terril L. Verplaetse, PhD, assistant professor of psychiatry, was selected to participate in the joint National Institute on Drug Abuse (NIDA) and National Institute on Alcohol Abuse and Alcoholism (NIAAA) Early Career Investigator Showcase (ECIS) on November 2.