Nader Atlasy, PhD
Research & Publications
Nader Atlasy Ph.D, is a Molecular Biologist who studies the complexity of the immune system in different contexts. During his doctoral studies in the lab of Prof. Henk Stunnenberg (promoter) and Dr. Joost Martens (co-promoter) at Radboud Institute for Molecular Life Sciences (RIMLS), the Netherlands, he applied cutting-edge technologies and bioinformatic approaches to investigate the whole transcriptome programs of the immune cells in the human small intestine and in Celiac disease where he characterized novel transcriptome signatures based on identification of different myeloid (sub)populations in the gut and established a comprehensive single-cell transcriptome atlas of immune cell compartment and further identified the underlying disease-related transcriptional programs of the cells. To gain more knowledge and training in the field of cancer immunology, he then joined the lab of Prof. Paul Coffer at Center for Molecular Medicine, Utrecht UMC, the Netherlands, where he studied the biology of regulatory T-cells (Treg) in human colorectal carcinomas (CRC). There he combined the single-cell transcriptome analysis and in vitro 3D co-culture system of human Tregs and CRC derived organoids and extensively studied the T-cell/cancer interactions to identify novel markers for development of target-based therapies. To further extend his knowledge and expertise in cancer immunobiology, he joined the lab of Prof. Markus Muschen, at Yale Center for Molecular and Cellular Oncology, Yale School of Medicine, to study the molecular programs and the mechanistic principles behind the human leukemia development.