https://medicine.yale.edu/lab/le-zhang/news-rss/?title=Latest%20News&orgId=121325 A selection of the latest research, academic, and other newsworthy developments at Le Zhang Lab en-us Copyright 2026 Yale School of Medicine Sat, 11 Jul 2026 03:06:17 Z https://news.yale.edu/2026/06/03/beyond-brain-organs-help-shape-nervous-systems-control-them https://news.yale.edu/2026/06/03/beyond-brain-organs-help-shape-nervous-systems-control-them A new Yale study finds that organs help direct the development of their own nervous systems, creating specialized networks that enable a two-way conversation between body and brain. Wed, 03 Jun 2026 20:00:00 Z https://medicine.yale.edu/lab/le-zhang/news-article/parkinsons-disease-associated-with-neuroinflammation-in-the-brain-new-analyses-reveal/ https://medicine.yale.edu/lab/le-zhang/news-article/parkinsons-disease-associated-with-neuroinflammation-in-the-brain-new-analyses-reveal/ Using single-cell transcriptomics and proteomics, Yale researchers have created a detailed cell atlas of brains affected by Parkinson’s disease. Thu, 07 Nov 2024 05:00:00 Z https://medicine.yale.edu/lab/le-zhang/news-article/revealing-communications-between-brain-and-body/ https://medicine.yale.edu/lab/le-zhang/news-article/revealing-communications-between-brain-and-body/ “This is the first time we actually know how different body signals are being represented through the vagal interoception system to the brain in a very precise and accurate manner,” says co-senior investigator Rui Chang, PhD. “We know that the brain can very precisely discriminate signals, but what is the biological reason for that discrimination?” Wed, 16 Mar 2022 04:00:00 Z https://medicine.yale.edu/ysm/yale-medicine-magazine/article/analyzing-the-aging-brain-offers-hope-for-dementia/ https://medicine.yale.edu/ysm/yale-medicine-magazine/article/analyzing-the-aging-brain-offers-hope-for-dementia/ The causes of dementia remain largely unknown to medicine. Scientists and researchers are working hard to connect what is known with gaps in treatment, and illuminating those mysteries that have yet to be resolved. Fri, 14 Jan 2022 05:00:00 Z https://medicine.yale.edu/lab/le-zhang/news-article/understanding-alzheimers-disease-single-cell-analysis-and-sex-specific-research-provide-new-insights/ https://medicine.yale.edu/lab/le-zhang/news-article/understanding-alzheimers-disease-single-cell-analysis-and-sex-specific-research-provide-new-insights/ Alzheimer's researchers identify sex-specific differences by studying single cells, revealing genetic activity that may help explain women's risk for AD. Mon, 11 May 2020 04:00:00 Z