2024
Unraveling the genetic tapestry of pediatric sarcomeric cardiomyopathies and masquerading phenocopies in Jordan
Azab B, Aburizeg D, Shaaban S, Ji W, Mustafa L, Isbeih N, Al-Akily A, Mohammad H, Jeffries L, Khokha M, Lakhani S, Al-Ammouri I. Unraveling the genetic tapestry of pediatric sarcomeric cardiomyopathies and masquerading phenocopies in Jordan. Scientific Reports 2024, 14: 15141. PMID: 38956129, PMCID: PMC11219879, DOI: 10.1038/s41598-024-64921-9.Peer-Reviewed Original ResearchConceptsExome sequencingSarcomere-related genesMitochondrial-related diseasesAt-risk family membersGenetic architectureGenetic landscapePathogenic variantsGene panelPediatric cardiomyopathyMolecular underpinningsGenetic testingPhenocopiesSarcomeric cardiomyopathiesGenesSequenceStorage disorderFamily membersAt-riskVariantsEarly interventionExomeFamilyGlycogen storage disorderHypertrophic cardiomyopathyCardiomyopathy
2021
Prevalence of and risk factors for depression among female Syrian refugees and Jordanians with chronic disease: a pilot study.
Sharp M, Parpia A, Ahram M, Mahmoud R, Khoshnood K. Prevalence of and risk factors for depression among female Syrian refugees and Jordanians with chronic disease: a pilot study. Eastern Mediterranean Health Journal 2021, 27: 1142-1152. PMID: 35137382, DOI: 10.26719/emhj.20.123.Peer-Reviewed Original ResearchConceptsChronic diseasesRisk factorsFemale Syrian refugeesGreater oddsDepression levelsChronic disease managementDeterminants of depressionChronic physical conditionsHealth intervention planningMultivariable ordinal regressionTimes greater oddsCross-sectional surveyMental health interventionsHigher depression levelsGenitourinary disordersComorbid depressionDisease burdenHealth characteristicsIdentified predictorsHealth statusHealth interventionsHigh levelsDiseasePilot studyDisorder statusExploring the bidirectional relationship between chronic disease and depression among female Syrian refugees and Jordanians: a qualitative analysis.
Sharp M, Kara J, Almidani S, Ahram M, Mahmoud R, Khoshnood K. Exploring the bidirectional relationship between chronic disease and depression among female Syrian refugees and Jordanians: a qualitative analysis. Eastern Mediterranean Health Journal 2021, 27: 1153-1161. PMID: 35137383, DOI: 10.26719/emhj.21.017.Peer-Reviewed Original ResearchConceptsChronic diseasesJordanian womenChronic illnessBidirectional relationshipMental healthIntersection of depressionNegative health care experiencesChronic disease interventionsHealth care experiencesSyrian womenContributors of morbidityComorbid depressionChronic conditionsFemale Syrian refugeesHealth care structuresMedical careNeuropsychiatric conditionsCare experiencesClinical settingDiseaseDisease interventionCare structuresWomenHealth careSensitive interventions
2019
Minds Under Siege: Cognitive Signatures of Poverty and Trauma in Refugee and Non‐Refugee Adolescents
Chen A, Panter‐Brick C, Hadfield K, Dajani R, Hamoudi A, Sheridan M. Minds Under Siege: Cognitive Signatures of Poverty and Trauma in Refugee and Non‐Refugee Adolescents. Child Development 2019, 90: 1856-1865. PMID: 31646618, PMCID: PMC6900191, DOI: 10.1111/cdev.13320.Peer-Reviewed Original ResearchConceptsCognitive signatureGender-balanced sampleNeurocognitive pathwaysExecutive functionPosttraumatic stressWM deficitsTrauma exposureInhibitory controlCognitive functionChildhood adversityMindSyrian refugeesImpact of warWMSubstantial violenceAdversityMemoryAdolescentsFearDeficitsRelative contributionCareful distinctionInsecurityAssociationMeasuresAssociation of MAOA genetic variants and resilience with psychosocial stress: A longitudinal study of Syrian refugees
Clukay CJ, Dajani R, Hadfield K, Quinlan J, Panter-Brick C, Mulligan CJ. Association of MAOA genetic variants and resilience with psychosocial stress: A longitudinal study of Syrian refugees. PLOS ONE 2019, 14: e0219385. PMID: 31314763, PMCID: PMC6636744, DOI: 10.1371/journal.pone.0219385.Peer-Reviewed Original ResearchConceptsPsychosocial stressPerceived Stress ScaleTrauma exposureProtective factorsGenetic variantsLow trauma exposureHigh trauma exposureMental health measuresMental health trajectoriesAdult mental healthSymptom scoresPsychosocial healthPsychosocial factorsEarly childhood traumaHealth measuresHealth trajectoriesMental healthTraumaMonoamine oxidaseTime pointsPsychosocial wellbeingLifelong effectsChildhood traumaHigher resilience levelsLongitudinal studyC-reactive protein, Epstein-Barr virus, and cortisol trajectories in refugee and non-refugee youth: Links with stress, mental health, and cognitive function during a randomized controlled trial
Panter-Brick C, Wiley K, Sancilio A, Dajani R, Hadfield K. C-reactive protein, Epstein-Barr virus, and cortisol trajectories in refugee and non-refugee youth: Links with stress, mental health, and cognitive function during a randomized controlled trial. Brain Behavior And Immunity 2019, 87: 207-217. PMID: 30797045, PMCID: PMC7327518, DOI: 10.1016/j.bbi.2019.02.015.Peer-Reviewed Original ResearchConceptsEpstein-Barr virus antibodiesC-reactive proteinHair cortisol concentrationsHealth outcomesBiomarker trajectoriesEpstein-Barr virusCell-mediated immunocompetenceStructured behavioral interventionsCRP levelsCortisol secretionInflammatory processVirus antibodiesMAIN OUTCOMECortisol concentrationsChildhood adversityTargeted interventionsCortisol trajectoriesCognitive functionBMIBehavioral interventionsMental healthTerms of responseInterventionWar-affected adolescentsPerceived stress
2018
Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan
Khuri-Bulos N, Lawrence L, Piya B, Wang L, Fonnesbeck C, Faouri S, Shehabi A, Vermund SH, Williams JV, Halasa NB. Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan. BMJ Open 2018, 8: e021898. PMID: 29780032, PMCID: PMC5961648, DOI: 10.1136/bmjopen-2018-021898.Peer-Reviewed Original ResearchMeSH KeywordsAdenoviridaeAntiviral AgentsFemaleHumansInfantIntensive Care UnitsJordanLength of StayMaleOxygen Inhalation TherapyPalivizumabParainfluenza Virus 1, HumanProspective StudiesRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus VaccinesRespiratory Syncytial Virus, HumanRespiratory Tract InfectionsRhinovirusRisk FactorsConceptsLonger LOSLength of stayAcute respiratory infectionsIntensive care unitRespiratory syncytial virusOxygen therapyMechanical ventilationHospitalisation ratesICU admissionIllness severityRespiratory virusesMedical conditionsExtended breast feedingRSV vaccine developmentProspective cohort studyUnderlying medical conditionsChemotherapy-associated neutropeniaHuman parainfluenza virusesYears of ageCohort studyRespiratory symptomsBreast feedingRespiratory infectionsCare unitSyncytial virus
2017
Exposure to verbal abuse and neglect during childbirth among Jordanian women
Alzyoud F, Khoshnood K, Alnatour A, Oweis A. Exposure to verbal abuse and neglect during childbirth among Jordanian women. Midwifery 2017, 58: 71-76. PMID: 29306737, DOI: 10.1016/j.midw.2017.12.008.Peer-Reviewed Original ResearchConceptsHealth care providersCare providersLast childbirthJordanian womenChild health centresVerbal abuseCross-sectional descriptive designMean ageMaternity settingsHealth centersWomen's ageConsequence of exposureCurrent studyWomen's exposureWomenChildbirthDescriptive designChildbirth methodAgeChildrenNeglect QuestionnairePrevalence of neglectFinal sampleAbuseExposureInsecurity, distress and mental health: experimental and randomized controlled trials of a psychosocial intervention for youth affected by the Syrian crisis
Panter‐Brick C, Dajani R, Eggerman M, Hermosilla S, Sancilio A, Ager A. Insecurity, distress and mental health: experimental and randomized controlled trials of a psychosocial intervention for youth affected by the Syrian crisis. Journal Of Child Psychology And Psychiatry 2017, 59: 523-541. PMID: 28967980, PMCID: PMC5972454, DOI: 10.1111/jcpp.12832.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent BehaviorBehavioral SymptomsChildFemaleFollow-Up StudiesHumansJordanMaleOutcome Assessment, Health CareProgram DevelopmentPsychiatric Status Rating ScalesPsychological TraumaPsychotherapy, GroupRefugeesSocial BehaviorStress Disorders, Post-TraumaticStress, PsychologicalSyriaConceptsProsocial behaviorTrauma exposurePost-traumatic stress reactionsPost-traumatic stress symptomsMental healthWar-affected youthMental health difficultiesWait-list controlMental health outcomesPsychosocial interventionsSmall effect sizesStress symptomsPsychosocial outcomesPerceived stressTreatment youthHealth difficultiesTrauma eventsPsychosocial programmingStress reactionsPsychosocial supportHuman distressEvidence baseTreat sampleYouthStructured activitiesResilience in Context: A Brief and Culturally Grounded Measure for Syrian Refugee and Jordanian Host‐Community Adolescents
Panter‐Brick C, Hadfield K, Dajani R, Eggerman M, Ager A, Ungar M. Resilience in Context: A Brief and Culturally Grounded Measure for Syrian Refugee and Jordanian Host‐Community Adolescents. Child Development 2017, 89: 1803-1820. PMID: 28617937, PMCID: PMC6208286, DOI: 10.1111/cdev.12868.Peer-Reviewed Original ResearchConceptsSyrian refugeesCommunity-level dimensionsYouth Resilience MeasureLifetime trauma exposureMental health symptomsThree-factor structureConflict settingsConfirmatory factor analysisQualitative workSocial responsibilityResource accessTrauma exposureRefugeesResilience scoresHealth symptomsCYRM-12Convergent validityMeasurement equivalenceResilience measuresCYRMItem loadingsFactor analysisResilienceUseful measureMeasures
2015
Natural history and epidemiology of respiratory syncytial virus infection in the Middle East: Hospital surveillance for children under age two in Jordan
Halasa N, Williams J, Faouri S, Shehabi A, Vermund SH, Wang L, Fonnesbeck C, Khuri-Bulos N. Natural history and epidemiology of respiratory syncytial virus infection in the Middle East: Hospital surveillance for children under age two in Jordan. Vaccine 2015, 33: 6479-6487. PMID: 26314623, PMCID: PMC7115487, DOI: 10.1016/j.vaccine.2015.08.048.Peer-Reviewed Original ResearchMeSH KeywordsEpidemiological MonitoringFemaleHospitalsHumansInfantInfant, NewbornJordanMaleMass SpectrometryNasal MucosaPharynxPrevalenceProspective StudiesReal-Time Polymerase Chain ReactionRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsReverse Transcriptase Polymerase Chain ReactionRisk FactorsVitamin DConceptsRespiratory syncytial virusRSV-positive childrenVitamin D levelsD levelsRespiratory virusesRisk factorsMedical conditionsBurden of RSVOxygen useMedian vitamin D levelNasal/throat swabsRespiratory syncytial virus infectionCause of bronchiolitisHeel stick bloodSyncytial virus infectionLack of breastfeedingSupplemental oxygen useHigh viral loadFuture RSV vaccinesYoung childrenReal-time RT-PCRRSV hospitalizationRespiratory symptomsRSV vaccineAntiviral therapySexual Offenses Among Children in the North of Jordan: An Exploratory Study
Shotar AM, Alzyoud S, Oweis A, Alhawamdeh KA, Khoshnood K. Sexual Offenses Among Children in the North of Jordan: An Exploratory Study. Journal Of Child Sexual Abuse 2015, 24: 538-554. PMID: 26301439, DOI: 10.1080/10538712.2015.1042181.Peer-Reviewed Original ResearchConceptsSexual violenceSexual offensesCases of rapeIndecent assaultMale victimsVulnerable segmentsSexual assaultViolenceOffensesAssaultExploratory studyImportant global health problemVictimsGlobal health problemNorth of JordanJordanMean ageFemale ratioRetrospective designPrevention strategiesOffendersNorthern regionHealth problemsPolicyAge groups
2010
Burden of respiratory syncytial virus in hospitalized infants and young children in Amman, Jordan
Khuri-Bulos N, Williams JV, Shehabi AA, Faouri S, Al Jundi E, Abushariah O, Chen Q, Ali SA, Vermund S, Halasa NB. Burden of respiratory syncytial virus in hospitalized infants and young children in Amman, Jordan. Infectious Diseases 2010, 42: 368-374. PMID: 20100116, PMCID: PMC2854220, DOI: 10.3109/00365540903496544.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsCost of IllnessFemaleHospitalizationHumansInfantJordanLength of StayMaleMiddle EastNosePharynxPrevalenceProspective StudiesRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus, HumanReverse Transcriptase Polymerase Chain ReactionRNA, ViralSex FactorsUnited StatesConceptsAcute respiratory infectionsMedian ageNose/throat swabsRespiratory syncytial virus seasonChildren's median ageRSV-negative childrenRSV-positive childrenSpecific viral causeLonger hospital stayHigher hospital chargesIntensive care unitRespiratory syncytial virusReal-time polymerase chain reactionLower median ageEffective preventive measuresJordanian infantsHospital stayHospitalized infantsRSV vaccineRespiratory infectionsCare unitHospital chargesSyncytial virusThroat swabsViral cause
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