2025
Delineating Empirically Plausible Causal Pathways to Suicidality Among People at Clinical High Risk for Psychosis
Bronstein M, Kummerfeld E, Bearden C, Cornblatt B, Walker E, Woods S, Mathalon D, Perkins D, Cadenhead K, Addington J, Cannon T, Vinogradov S. Delineating Empirically Plausible Causal Pathways to Suicidality Among People at Clinical High Risk for Psychosis. Journal Of Psychopathology And Clinical Science 2025, 134: 239-250. PMID: 39913476, DOI: 10.1037/abn0000969.Peer-Reviewed Original ResearchConceptsClinical high riskNorth American Prodrome Longitudinal StudyClinical high-risk samplesAttenuated psychosis symptomsPathways to suicideSuicide risk reductionPsychosis symptomsCausal pathwaysDepressed moodPsychosisIntervention effortsSelf-deprecationSuicideLongitudinal studyMeasurement time pointsStudy timepointsHigh riskSymptomsInterventionHopelessnessMoodTime pointsDepressionIndividualsDirect causesThe association between internet-use-disorder symptoms and loneliness: a systematic review and meta-analysis with a categorical approach
Mestre-Bach G, Paiva U, San Martín Iniguez L, Beranuy M, Martín-Vivar M, Mallorquí-Bagué N, Normand E, Chicote M, Potenza M, Arrondo G. The association between internet-use-disorder symptoms and loneliness: a systematic review and meta-analysis with a categorical approach. Psychological Medicine 2025, 55: e77. PMID: 40071718, DOI: 10.1017/s0033291725000376.Peer-Reviewed Original ResearchConceptsInternet-use disordersSystematic reviewMeta-analysisInternet-useInternet use disorderRandom-effects modelWeb of ScienceDegree of lonelinessUCLA Loneliness ScaleStatistical poolingQuantify associationsOdds ratioCohen's dDisorder symptomsGreater lonelinessMeta-regressionPooled differenceEffect sizePre-registeredUCLA-LonelinessLonelinessEffects of ageCategorical approachSymptomsGroup of individualsQuantifying associations between socio-spatial factors and cognitive development in the ABCD cohort
Osayande N, Marotta J, Aggarwal S, Kopal J, Holmes A, Yip S, Bzdok D. Quantifying associations between socio-spatial factors and cognitive development in the ABCD cohort. Nature Computational Science 2025, 5: 221-233. PMID: 40114020, DOI: 10.1038/s43588-025-00774-0.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBayes TheoremChildCognitionCohort StudiesFemaleHumansMaleSocial ClassSocioeconomic FactorsConceptsAdolescent Brain Cognitive Development StudyCognitive developmentUS Census dataCognitive Development StudyBayesian multilevel regressionPost-stratificationSocio-spatial factorsSociodemographic disparitiesSocioeconomic statusABCD cohortSociodemographic variablesBayesian multilevel modelsQuantify associationsInter-individual differencesMultilevel regressionPublic healthMultilevel modelsCensus dataInterpretation of model predictionsDemographic groupsDevelopment studiesHolistic explanationHomogeneous representationModeling frameworkMounting demandIdentifying the Financial Toxicity Experiences of Childhood Cancer Survivors Through Partnership With a Community Organization Serving Rural and Minoritized Families
Benedict C, Bloomer K, Billman E, Smith M, Boynton H, Schapira L, Smith S. Identifying the Financial Toxicity Experiences of Childhood Cancer Survivors Through Partnership With a Community Organization Serving Rural and Minoritized Families. Psycho-Oncology 2025, 34: e70120. PMID: 40097346, DOI: 10.1002/pon.70120.Peer-Reviewed Original ResearchConceptsAYA survivors of childhood cancerSurvivors of childhood cancerChildhood cancerAYA survivorsFinancial toxicityAdolescent/young adultPerspectives of staff membersNon-English language preferenceStaff membersCancer support organizationsThematic analysis approachCommunity-based organizationsRural regionsParental employmentIndirect medical costsNeeds assessment studySemi-structured interviewsMedical visitsVulnerable populationsLanguage preferenceInsurance coverageMedical costsQualitative dataRural areasMinoritized familiesATGL links insulin dysregulation to insulin resistance in adolescents with obesity and hepatosteatosis
Slusher A, Santoro N, Vash-Margita A, Galderisi A, Hu P, Tokoglu F, Li Z, Tarabra E, Strober J, Vatner D, Shulman G, Caprio S. ATGL links insulin dysregulation to insulin resistance in adolescents with obesity and hepatosteatosis. Journal Of Clinical Investigation 2025, 135: e184740. PMID: 40091831, PMCID: PMC11910223, DOI: 10.1172/jci184740.Peer-Reviewed Original ResearchConceptsHyperinsulinemic-euglycemic clampSubcutaneous adipose tissueInsulin resistanceAdipose triglyceride lipaseInsulin infusionOral glucose tolerance testAbdominal fat distributionGlucose tolerance testMeasuring abdominal fat distributionLower liver fatActivating adipose triglyceride lipaseMetabolic disease riskLiver fat contentEctopic lipid storageFUNDINGThis workAdipose tissue lipolysisInhibition of adipose tissue lipolysisSubcutaneous adipose tissue samplesFat distributionTolerance testInsulin exposureLiver fatInfusionGlycerol turnoverAdipose tissueEvaluating the Effect of Epigallocatechin Gallate (EGCG) in Reducing Folate Levels in Reproductive Aged Women by MTHFR and DHFR Genotype in Combination With Letrozole or Clomiphene
Johnson J, Siblini H, Al‐Hendy A, Segars J, González F, Taylor H, Singh B, Carson S, Christman G, Huang H, Dangi B, Zhang H. Evaluating the Effect of Epigallocatechin Gallate (EGCG) in Reducing Folate Levels in Reproductive Aged Women by MTHFR and DHFR Genotype in Combination With Letrozole or Clomiphene. Clinical And Translational Science 2025, 18: e70189. PMID: 40077973, PMCID: PMC11903501, DOI: 10.1111/cts.70189.Peer-Reviewed Original ResearchConceptsEpigallocatechin-3-gallateFolate levelsUterine fibroidsClinical trialsGreen tea extractAssociated with folate deficiencyPresence of MTHFRWomen of childbearing ageSerum folate levelsReduced folate levelsActive clinical trialsReproductive-age womenEffect of epigallocatechin gallateDhfr genotypeDHFR polymorphismTea extractDaily doseClomiphene citrateUnexplained infertilityFolate deficiencyChildbearing ageClinical studiesTreated womenFibroidsLetrozoleCannabis legalization and increasing cannabis use in the United States: Data from urine toxicology testing in emergency room patients
Fink D, Samples H, Malte C, Olfson M, Wall M, Alschuler D, Simpson T, Mannes Z, Saxon A, Hasin D. Cannabis legalization and increasing cannabis use in the United States: Data from urine toxicology testing in emergency room patients. International Journal Of Drug Policy 2025, 138: 104765. PMID: 40058102, PMCID: PMC11967342, DOI: 10.1016/j.drugpo.2025.104765.Peer-Reviewed Original ResearchConceptsUrine drug screensCannabis use disorderMedical cannabis lawsVeterans Health AdministrationCannabis useRecreational cannabis lawsRates of cannabis use disordersCannabis lawsEmergency departmentIndicators of cannabis useUrine toxicology testsIncreased cannabis useDifference-in-differences analysisLegalized cannabis useEmergency room patientsSelf-reported dataBinomial regression modelsED visitsED patientsHealth AdministrationCannabis involvementPatient samplesPatientsUse disorderCannabisEvaluating community knowledge of tuberculosis preventive therapy in rural South Africa
Foppiano Palacios C, Moll A, Shrestha R, Kompala T, Davis J, Charalambous S, Chimoyi L, Chihota V, Andrews L, Shenoi S. Evaluating community knowledge of tuberculosis preventive therapy in rural South Africa. BMC Public Health 2025, 25: 918. PMID: 40055618, DOI: 10.1186/s12889-025-21719-2.Peer-Reviewed Original ResearchConceptsKnowledge of TBTB knowledgeExploratory factor analysisCommunity membersPublic health educationRural South AfricaCross-sectional studyPreventive therapyTuberculosis preventive therapyMultivariate linear regressionLinear regressionHealth educationChi-square testMedian scoreCounseling effortsCommunity eventsDescriptive statisticsEvaluate knowledgeTesting initiativesCultural beliefsTB incidenceCommunity knowledgeKwaZulu NatalSouth AfricaFactor analysisPerinatal exposure to ambient fine particle air pollution and risk of childhood ewing sarcoma in a population-based case-control study in California (1988–2015)
Clark C, Wang R, Wiemels J, Metayer C, Deziel N, Ma X. Perinatal exposure to ambient fine particle air pollution and risk of childhood ewing sarcoma in a population-based case-control study in California (1988–2015). Environmental Health 2025, 24: 6. PMID: 40055781, DOI: 10.1186/s12940-025-01159-6.Peer-Reviewed Original ResearchConceptsHispanic childrenSarcoma riskControls frequency-matched to casesFrequency-matched to casesBirth yearPopulation-based case-control studyOdds ratioPM2.5 exposureConfidence intervalsAir pollution exposureCalifornia birth cohortNon-Hispanic childrenAmbient PM2.5 exposureFine particle air pollutionCase-control studyAmbient fine particulate matterHigher PM2.5 levelsMaternal residenceCancer riskMaternal educationPotential disparitiesBirth cohortHispanic ethnicityElevated oddsLinkage studiesKleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women
Munguía L, Baenas-Soto I, Granero R, Fábregas-Balcells M, Gaspar-Pérez A, Rosinska M, Potenza M, Cuquerella Á, Tapia-Martínez J, Cabús-Grange R, Taranilla-Castro A, Macharé-Alberni M, Talón-Navarro M, Fernández-Aranda F, Jiménez-Murcia S. Kleptomania on the impulsive–compulsive spectrum. Clinical and therapeutic considerations for women. Scientific Reports 2025, 15: 7886. PMID: 40050325, PMCID: PMC11885670, DOI: 10.1038/s41598-025-85705-9.Peer-Reviewed Original ResearchConceptsImpulsive-compulsive spectrumDSM-5 criteriaClinical groupsDSM-5Personality featuresSemi-structured clinical interviewTreatment outcomesHarm avoidance scoresCognitive behavioral treatmentHealthy control individualsSample of female patientsImpact treatment outcomesPoor treatment outcomesCompulsive featuresBehavioral treatmentHigher impulsivityAvoidance scoresClinical interviewKleptomaniaInvestigate treatment outcomesCharacteristics of peopleFemale participantsPsychopathologyClinical samplesTreatment approachesGlobal, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021
Collaborators G, Kerr J, Patton G, Cini K, Abate Y, Abbas N, Al Magied A, ElHafeez S, Abd-Elsalam S, Abdollahi A, Abdoun M, Abdulah D, Abdulkader R, Abdullahi A, Abeywickrama H, Abie A, Abiodun O, Abohashem S, Abtahi D, Abualruz H, Abubakar B, Abu-Gharbieh E, Abukhadijah H, Abu-Rmeileh N, Aburuz S, Abu-Zaid A, Adams L, Adane M, Addo I, Adedokun K, Adegoke N, Adesola R, Adetunji J, Adeyeoluwa T, Adiga U, Adnani Q, Afify A, Afolabi A, Afzal M, Afzal S, Agampodi S, Aghamiri S, Sobrinho C, Agyemang-Duah W, Ahinkorah B, Ahlstrom A, Ahmad A, Ahmad D, Ahmad F, Ahmad M, Ahmad N, Ahmad S, Ahmed A, Ahmed H, Ahmed L, Ahmed M, Ahmed M, Ahmed S, Ajami M, Akkaif M, Akrami A, Al Hamad H, Al Hasan S, Al Ta'ani Z, Al Thaher Y, Alalwan T, Al-Aly Z, Alam K, Al-amer R, Alansari A, Al-Ashwal F, Albashtawy M, Alemayehu B, Algammal A, Alhabib K, Alhuwail D, Ali A, Ali E, Ali M, Ali M, Ali R, Ali W, Alif M, Alimohamadi Y, Al-Jabi S, Aljofan M, Aljunid S, Alkhatib A, Almahmeed W, Al-Marwani S, Alomari M, Alqahtani S, Alqarni A, Alrawashdeh A, Alrimawi I, Alrousan S, Alshahrani N, Altaany Z, Altaf A, Alvi F, Alvis-Guzman N, Al-Wardat M, Al-Worafi Y, Aly H, Aly S, Alzoubi K, Mohammadi M, Amera T, Amiri S, Amu H, Amugsi D, Amusa G, Ananda R, Ancuceanu R, Ansari M, Ansari S, Anuoluwa B, Anuoluwa I, Anvari S, Anwar S, Anyasodor A, Arab J, Arabloo J, Arafat M, Aravkin A, Areda D, Aregawi B, Arifin H, Armocida B, Ärnlöv J, Arooj M, Arora A, Artamonov A, Artanti K, Arumugam A, Asghari-Jafarabadi M, Ashraf T, Asiamah-Asare B, Astell-Burt T, Athari S, Atorkey, Atreya A, Aumoldaeva Z, Awoke M, Awotidebe A, Aychiluhm S, Azimi A, Aziz S, Aziz S, Azzam A, Azzolino D, Babashahi M, Babu G, Badran A, Bagheri N, Bai R, Baig A, Bakkannavar S, Balakrishnan S, Baltatu O, Bam K, Banik R, Barati S, Bardhan M, Barqawi H, Barquera S, Barrow A, Barua L, Bastan M, Basu S, Bayat R, Bayih M, Bayleyegn N, Beeraka N, Behera P, Ramirez D, Bello U, Belo L, Bennett D, Bergami M, Berhe K, Berihun A, Bhadoria A, Bhala N, Bharadwaj R, Bhardwaj N, Bhardwaj P, Bhaskar S, Bhat A, Bhattacharjee P, Bhatti G, Bhatti J, Bilgin C, Bisignano C, Biswas B, Peroni B, Bjertness E, Bjørge T, Boloor A, Boppana S, Bosoka S, Bouaoud S, Boyko E, Braithwaite D, Brazo-Sayavera J, Brenner H, Bryazka D, Bugiardini R, Bui L, Bustanji Y, Butt N, Butt Z, Barsbay M, Calina D, Cámera L, Campos L, Cao S, Capodici A, Carletti C, Carvalho A, Carvalho M, Cattafesta M, Cattaruzza M, Cegolon L, Cembranel F, Cerin E, Cernigliaro A, Chadwick J, Chakraborty C, Chandrasekar E, Chang J, Chattu V, Chaudhary A, Chaurasia A, Chen A, Chen H, Chew N, Chi G, Chimoriya R, Ching P, Chitheer A, Choi D, Chong B, Chong C, Chopra H, Chopra S, Chou H, Choudhari S, Chung S, Chung S, Chutiyami M, Cogen R, Columbus A, Conrad N, Criqui M, Cruz-Martins N, da Silva A, Dadras O, Dai X, Dalakoti M, D'Amico E, Dandona L, Dandona R, D'Anna L, Danpanichkul P, Darcho S, Soltani R, Dash N, Davletov K, Dehghan A, Denova-Gutiérrez E, Molla M, Dergaa I, Desale A, Devanbu V, Devegowda D, Dhali A, Dhungel B, Diaz D, Dinu M, Chi T, do Prado C, Dodangeh M, Doegah P, Dohare S, Dokova K, Doku P, Dolatkhah N, D'Oria M, Dorostkar F, Doshi O, Doshi R, Dowou R, Du M, Dumith S, Dumuid D, Duncan B, Dutta S, Ebrahimi A, Edvardsson K, Sedeh A, Ekholuenetale M, Arab R, Bayoumy I, Eladl M, El-Ashker S, Elbarazi I, Elgendy I, Elhadi M, El-Metwally A, Elmonem M, Elnaem M, Elsheikh R, Eltaha C, Emeto T, Eslami M, Fabin N, Fadavian H, Fagbamigbe A, Fakhradiyev I, Faraji S, Farinha C, Faris M, Faris P, Kouhanjani M, Farooque U, Farrokhpour H, Fasusi S, Fazeli P, Fazylov T, Feizkhah A, Fekadu G, Feng X, Fernandez-Jimenez R, Ferreira N, Foigt N, Folayan M, Fomenkov A, Foroumadi R, Rodrigues C, Foschi M, Francis K, Franklin R, Gába A, Gadanya M, Gaidhane A, Galali Y, Gallus S, Ganesan B, Gangachannaiah S, Gebregergis M, Gebrehiwot M, Getacher L, Getie M, Ghadirian F, Ghazy R, Gil A, Gill T, Gillum R, Girmay A, Golechha M, Goleij P, Goulart A, Grada A, Grivna M, Grover A, Guan Z, Guarducci G, Gubari M, Guha A, Gulati S, Gunawardane D, Guo Z, Gupta B, Gupta R, Gupta R, Gupta V, Gutiérrez-Murillo R, Guzman-Esquivel J, Hadi N, Hadian Z, Hamdy N, Hamidi S, Hanif A, Hanifi N, Hankey G, Haq A, Haro J, Hasan F, Hashempour R, Hashempur M, Hasnain S, Hassan A, Hassan N, Hassanipour S, Rad A, Havmoeller R, Hay S, Hebert J, Hezam K, Hiraike Y, Hoang M, Holla R, Hossain A, Hosseinzadeh H, Hostiuc M, Hostiuc S, Htay Z, Hu M, Hu Y, Humayun A, Hundie T, Husseiny M, Hussien F, Huynh H, Hwang B, Ibrahim R, Ibrayeva A, Ikeda N, Ilesanmi O, Ilic I, Ilic M, Inbaraj L, Inok A, Iqbal K, Islam S, Islam F, Islam R, Islam M, Ismail N, Iso H, Isola G, Ituka M, Iwagami M, Iwu-Jaja C, Iyasu A, Jacob L, Jaffar S, Jahrami H, Jain A, Jain R, Jairoun A, Jakovljevic M, Javaid S, Jayapal S, Jayaram S, Jebasingh F, Jee S, Jema A, Jeswani B, Jonas J, Joseph N, Joshua C, Jozwiak J, Jürisson M, Kaambwa B, Kabir A, Kadashetti V, Kakkar A, Kalra S, Kanaan S, Kankam S, Kanmanthareddy A, Kanmodi K, Kantar R, Kar D, Karajizadeh M, Karakasis P, Behnagh A, Karimzadhagh S, Kassebaum N, Kauppila J, Kayode G, Kedir S, Kehagias D, Keshwani A, Kesse-Guyot E, Keykhaei M, Khajuria H, Khalili P, Khalilian A, Khalis M, Khan A, Khan M, Khan A, Khan M, Khan M, Khan M, Khan N, Khanal V, Khanmohammadi S, Khatatbeh M, Kheirkhah M, Khidri F, Khokhar M, Khosla A, Khosravi S, Khosrowjerdi M, Khusun H, Kim G, Kim J, Kim J, Kim M, Kim Y, Kimokoti R, Kisa A, Kishore L, Shivakumar K, Kokkorakis M, Kompani F, Korzh O, Kostev K, Laxminarayana S, Kretchy I, Kua C, Defo B, Kuddus M, Kulimbet M, Kulkarni V, Kumar G, Kumar V, Kundu S, Kunutsor S, Kurmi O, Kurniasari M, Kusuma D, Kytö V, La Vecchia C, Lacey B, Lahariya C, Lai D, Landires I, Larijani B, Lassi Z, Le H, Le N, Lee H, Lee M, Lee P, Lee S, Lee W, Li A, Li M, Li W, Li Y, Lim S, Lin J, Lin Q, Lindholm D, Lindstedt P, Liu J, Lo J, López-Gil J, Lorkowski S, Lucchetti G, Lugo A, Lutambi A, Feei Z, Gómez J, Maghbouli N, Mahalleh M, Mahmood N, Majeed A, Makris K, Rad E, Malekzadeh R, Malhotra K, Malik A, Malik I, Malta D, Mamun A, Manu E, Marateb H, Marino M, Marjani A, Martinez-Piedra R, Martorell M, März W, Marzouk S, Masrouri S, Mathangasinghe Y, Matozinhos F, Matthias T, Mattiello R, Maugeri A, Mazidi M, McPhail S, Mechili E, Salas M, Mehmood A, Mehrabani-Zeinabad K, Meto T, Meles H, Mendoza W, Menezes R, Mengistie E, Meo A, Mestrovic T, Mettananda C, Mettananda S, Miao H, Miller T, Ming W, Mirrakhimov E, Misganaw A, Mitiku H, Mittal M, Mohamed J, Mohamed M, Mohamed N, Mohammad T, Mohammad-Alizadeh-Charandabi S, Mohammadian-Hafshejani A, Mohammadzadeh I, Mohammed S, Mokdad A, Monasta L, Mondello S, Moni M, Namin S, Ghalibaf A, Moradi Y, Morrison S, Motappa R, Mubarik S, Mulita F, Mullany E, Munkhsaikhan Y, Murillo-Zamora E, Murray C, Musa S, Mustafa G, Muthu S, Mwita J, Myung W, Nafiu A, Nagel G, Naik G, Naik H, Nambi G, Nangia V, Nargus S, Nascimento G, Nassar M, Nauman J, Naureen Z, Navaratna S, Nawsherwan, Nayak B, Nazri-Panjaki A, Negahdary M, Negoi I, Negoi R, Nematollahi S, Nepal S, Netsere H, Ng M, Ngunjiri J, Nguyen D, Nguyen P, Phuong The Nguyen, Niazi R, Nieddu L, Niknam M, Nikolouzakis T, Nikoobar A, Nkeck J, Nomura S, Noor S, Noreen M, Noubiap J, Nouri M, Nri-Ezedi C, Nugen F, Nuñez-Samudio V, Nur A, Nyande F, Nzoputam C, Oancea B, O'Connell E, Odetokun I, Ofakunrin A, Oguta J, Oh I, Okati-Aliabad H, Okeke S, Okekunle A, Okonji O, Olagunju A, Olalusi O, Olasehinde T, Oliveira A, Oliveira G, Oluwafemi Y, Omar H, Bali A, Omer N, Ong S, Ordak M, Ortiz A, Osborne A, Osman W, Otoiu A, Oumer A, Ouyahia A, Owolabi M, Owusu I, Oyebola K, Oyelade T, A M, Padron-Monedero A, Padubidri J, Palicz T, Panda S, Panda-Jonas S, Pandey A, Pandi-Perumal S, Pant S, Pardhan S, Parekh U, Parija P, Parikh R, Park E, Passera R, Patel J, Patoulias D, Paudel S, Peprah, Pereira M, Perico N, Perna S, Petcu I, Petermann-Rocha F, Pham H, Pham T, Pirouzpanah S, Polibin R, Popovic D, Potani I, Pourghazi F, Pourshams A, Pradhan J, Pradhan P, Prasad M, Prashant A, Prates E, Puvvula J, Qattea I, Qiao Y, Radhakrishnan V, Radojˇić M, Raggi C, Rahman F, Rahman M, Rahman M, Rahman M, Rahman M, Rahmanian M, Rahmanian V, Rahmati M, Kumar R, Raimondo I, Raj J, Rajput P, Ramadan M, Ramasamy C, Ramasamy S, Ramazanu S, Rana K, Ranabhat C, Rao M, Rao S, Rashedi S, Rashidi M, Rasouli-Saravani A, Rathish D, Rauniyar S, Rautalin I, Rawaf D, Rawaf S, Redwan E, Rege S, Rehman A, Reis-Mendes A, Remuzzi G, Rezaei N, Rezaeian M, Rhee T, Rocha-Gomes J, da Silva T, Rodriguez J, Roever L, Rohloff P, Romadlon D, Rony M, Roshandel G, Rout H, Roy N, Rwegerera G, Saad A, Saber-Ayad M, Sabzmakan L, Sadarangani K, Saddik B, Sadeghi M, Saeed U, Sagoe D, Sharif-Askari F, Sahebkar A, Sahoo S, Sajadi S, Sajid M, Salami A, Salaroli L, Saleem S, Saleh M, Salem M, Salihu D, Salimi S, Samy A, Santric-Milicevic M, Sarkar T, Sarmadi M, Sarode G, Sarode S, Sassano M, Saulam J, Sawhney M, Saxena S, Saya G, Schinckus C, Schmidt M, Schuermans A, Selvaraj S, Sendekie A, Sengupta P, Senol Y, Senthilkumaran S, Sepanlou S, Sethi Y, Seylani A, Shafie M, Shah S, Shahid S, Shahwan M, Shamim M, Shams-Beyranvand M, Shamsutdinova A, Shanawaz M, Shannawaz M, Sharath M, Sharifan A, Sharma M, Sharma U, Sharma V, Sheida F, Shenoy R, Shetty P, Shiferaw D, Shin M, Lapari M, Shiri R, Shittu A, Shool S, Shorofi S, Shrestha G, Shrestha R, Shuval K, Si Y, Sibuyi N, Siddig E, Siervo M, Silva D, Silva L, Singh A, Singh B, Singh H, Singh J, Singh K, Singh L, Singh M, Singh P, Singh S, Skryabina A, Smith A, Smith G, Soliman S, Soraneh S, Spartalis M, Srichawla B, Stanikzai M, Starodubova A, Straif K, Stubbs P, Subramaniyan V, Odidi M, Sulkowski A, Meo A, Sun Z, Sunny S, Sunuwar D, Swain C, Szarpak L, Y S, Tabarés-Seisdedos R, Tabatabaei S, Malazy O, Tabatabaeizadeh S, Tabatabai S, Tabche C, Tabish M, Taiba J, Tampa M, Tamuzi J, Tan K, Tanwar M, Tariq S, Tat N, Temsah M, Temsah R, Teramoto M, Terefa D, Tewari J, Thangaraju P, Thapar R, Thavamani A, Thirunavukkarasu S, Thomas J, Tiruneh S, Tiruye T, Titova M, Tiwari K, Tomo S, Tonelli M, Touvier M, Tovani-Palone M, Trabelsi K, Tran N, Tran T, Duc N, Trico D, Truyen T, Tsegay G, Tumurkhuu M, Tye S, Udoakang A, Ullah A, Ullah S, Ullah S, Umair M, Umar L, Umar U, Unim B, Upadhya D, Upadhyay E, Usman J, Ustunsoz D, Vaezghasemi M, Vaithinathan A, Van den Eynde J, Varghese J, Vasankari T, Vaziri S, Vellingiri B, Venketasubramanian N, Verma M, Verras G, Villalobos-Daniel V, Vladimirov S, Vlassov V, Vollset S, Vukovic R, Wahiduzzaman M, Wang C, Wang S, Wang X, Wang Y, Weerakoon K, Wei F, Wicaksana A, Wickramasinghe D, Wickramasinghe N, Willeit P, Wojewodzic M, Xia Q, Xiao G, Xie W, Xu S, Xu X, Yahya G, Yamagishi K, Yano Y, Yao H, Yarahmadi A, Yaribeygi H, Ye P, Yesuf S, Yin D, Yon D, Yonemoto N, Yu C, Yuan C, Yuce D, Yunusa I, Zamagni G, Zastrozhin M, Zeariya M, Zhang C, Zhang H, Zhang J, Zhang L, Zhang X, Zhang Z, Zhao H, Zheng D, Zhong A, Zhong C, Zhou J, Zhu B, Zhumagaliuly A, Zielińska M, Zitoun O, Zoghi G, Zou Z, Zyoud S, Gakidou E, Sawyer S, Azzopardi P. Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021. The Lancet 2025, 405: 785-812. PMID: 40049185, PMCID: PMC11920006, DOI: 10.1016/s0140-6736(25)00397-6.Peer-Reviewed Original ResearchConceptsHigh-income North AmericaSouthern sub-Saharan AfricaExcess body massObesity prevalenceAged 5Non-communicable diseases in adulthoodGlobal burdenGlobal Burden of Disease StudyBurden of Disease StudyGlobal Burden of DiseaseSub-Saharan AfricaCentral Latin AmericaNational prevalence of childrenRisk Factors StudySpatiotemporal Gaussian process regression modelingBurden of diseaseMales aged 5Prevalence of childrenConsequences of obesityOverweight prevalenceAdolescent overweightAge-standardisedBody massIndividuals aged 5Females aged 5Retention and dropout from sublingual and extended-release buprenorphine treatment: A comparative analysis of data from a nationally representative sample of commercially-insured people with opiod use disorder in the United States
Ivasiy R, Madden L, Johnson K, Machavariani E, Ahmad B, Oliveros D, Tan J, Kil N, Altice F. Retention and dropout from sublingual and extended-release buprenorphine treatment: A comparative analysis of data from a nationally representative sample of commercially-insured people with opiod use disorder in the United States. International Journal Of Drug Policy 2025, 138: 104748. PMID: 40020306, PMCID: PMC12045481, DOI: 10.1016/j.drugpo.2025.104748.Peer-Reviewed Original ResearchConceptsOpioid use disorderSL-BUPXR-BUPUse disorderRetrospective cohort studyExtended-release buprenorphineReduce treatment discontinuationDays of supplyTreatment discontinuationSublingual buprenorphineReduce overdose riskBuprenorphine treatmentCohort studyHigh dosesPrimary outcomeImpact of dosagePatientsBuprenorphineMonthsMg/dayCommercially-insured individualsProportion of individualsOpioidOverdose riskImprove health outcomesRacism-related stress, health outcomes, substance use, and PrEP attitudes among Asian sexual minority men
Chin L, Kershaw T, Hernandez-Ramirez R, Ramos S. Racism-related stress, health outcomes, substance use, and PrEP attitudes among Asian sexual minority men. Scientific Reports 2025, 15: 6994. PMID: 40016341, PMCID: PMC11868514, DOI: 10.1038/s41598-025-91794-3.Peer-Reviewed Original ResearchConceptsAsian American Racism-Related Stress InventoryRacism-related stressSexual minority menHealth outcomesIncreased substance useMinority menSubstance useBehavioral Risk Factor Surveillance SystemRisk Factor Surveillance SystemSexual minority identitySecondary analysis of dataHIV self-testingNational Survey on Drug Use and HealthDecreased psychological well-beingDrug Use and HealthPsychological well-beingMinority identityPrEP attitudesRacial inequalityIntersecting factorsPhysical healthSocietal discriminationPolitical climateStress InventoryRacial discriminationSingle cell analysis identifies distinct CD4 + T cells associated with the pathobiology of pediatric obesity related asthma
Thompson D, Wabara Y, Duran S, Reichenbach A, Chen L, Collado K, Yon C, Greally DMed J, Rastogi D. Single cell analysis identifies distinct CD4 + T cells associated with the pathobiology of pediatric obesity related asthma. Scientific Reports 2025, 15: 6844. PMID: 40000680, PMCID: PMC11861978, DOI: 10.1038/s41598-025-88423-4.Peer-Reviewed Original ResearchConceptsCD4+ T cellsT cell subtypesT cellsSteroid resistanceTh1 inflammationObese asthmaTh1 responseCentral memory T cellsObese asthma phenotypeEffector T cellsMemory T cellsObesity-related asthmaCD4+ T cell subtypesPediatric obesity-related asthmaT helper 1Healthy-weight controlsPulmonary function deficitsCD4Th1Asthma phenotypesGlucocorticoid receptorSingle-cell transcriptomicsFunctional deficitsInflammationSteroidsChronotherapeutic intervention targeting emotion regulation brain circuitry, symptoms, and suicide risk in adolescents and young adults with bipolar disorder: a pilot randomised trial
Kim J, Sankar A, Marks R, Carrubba E, Lecza B, Quatrano S, Spencer L, Constable R, Pittman B, Lebowitz E, Silverman W, Swartz H, Blumberg H. Chronotherapeutic intervention targeting emotion regulation brain circuitry, symptoms, and suicide risk in adolescents and young adults with bipolar disorder: a pilot randomised trial. BMJ Mental Health 2025, 28: e301338. PMID: 39971594, PMCID: PMC11840897, DOI: 10.1136/bmjment-2024-301338.Peer-Reviewed Original ResearchConceptsBipolar disorderEmotion regulationSuicide riskBrain circuitryChronotherapeutic interventionsEmotional face stimuliLeft amygdala responseRisk of bipolar disorderTargeting emotion regulationReduce suicide riskHigher suicide riskYoung adultsFunctional MRI dataPost-treatment improvementAmygdala responsePotential intervention targetsEmotion dysregulationMania symptomsMood episodesFace stimuliCircuitry dysfunctionRegulation therapyDaily rhythmsWeekly sessionsSelf-monitoringGlobal, regional, and national burden of suicide, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Collaborators G, Weaver N, Bertolacci G, Rosenblad E, Ghoba S, Cunningham M, Ikuta K, Moberg M, Mougin V, Han C, Wool E, Abate Y, Adewuyi H, Adnani Q, Adzigbli L, Afolabi A, Agampodi S, Ahinkorah B, Ahmad A, Ahmad D, Ahmad S, Ahmed A, Ahmed H, Al Hamad H, Al-Ajlouni Y, Al-amer R, Albashtawy M, Aldhaleei W, Ali S, Ali W, Alomari M, Alsabri M, Alvis-Guzman N, Al-Worafi Y, Amindarolzarbi A, Amiri S, Andrei T, Anvari S, Arabloo J, Areda D, Artamonov A, Ashraf T, Athari S, Atout M, Azzam A, Badiye A, Baghcheghi N, Bahramian S, Banach M, Barker-Collo S, Bärnighausen T, Barrow A, Bashiri A, Bashiru H, Bastan M, Batra K, Batra R, Bayati M, Benjet C, Benzian H, Bertuccio P, Bhagavathula A, Bhattacharjee P, Bills C, Boppana S, Borges G, Borhany H, Bustanji Y, dos Santos F, Castelpietra G, Caye A, Cenderadewi M, Chandika R, Chandrasekar E, Charalampous P, Chen Y, Chimoriya R, Chopra H, Choudhari S, Chu D, Chukwu I, Chutiyami M, Cowden R, Dachew B, Dadras O, Dai X, Dalal K, Dandona L, Dandona R, Darcho S, Soltani R, Dávila-Cervantes C, de la Torre-Luque A, Debopadhaya S, Degenhardt L, Delgado-Enciso I, Dervišević E, Diaz M, Dongarwar D, Doshi O, Dsouza H, Dumith S, Duraisamy S, Eboreime E, Efendi F, Ekholuenetale M, Arab R, Elhadi M, ELNahas G, Eltaha C, Haque S, Eskandarieh S, Fahim A, Faro A, Fatehizadeh A, Fazeli P, Feizkhah A, Fekadu G, Ferreira N, Fischer F, Franklin R, Fridayani N, Gajdács M, Gandhi A, Ganesan B, Gebregergis M, Gebrehiwot M, Gebremeskel T, Getie M, Ghadimi D, Ghailan K, Ghashghaee A, Gholamrezanezhad A, Goleij P, Grada A, Grivna M, Guan S, Gulati S, Gupta S, Gutiérrez R, Gutiérrez-Murillo R, Hamilton E, Hanifi N, Hasan I, Tabatabaei M, Hay S, Heidari M, Hemmati M, Hoan N, Hosseinzadeh M, Hostiuc S, Huang J, Huynh H, Ibitoye S, Ilesanmi O, Ilic I, Ilic M, Immurana M, Inok A, Iwu C, Jahrami H, Jaka S, Yengejeh R, Ji Z, Jin S, Joseph N, Joshua C, Jozwiak J, Kabir Z, Kadashetti V, Kanmodi K, Kantar R, Kapoor N, Karaye I, Karmakar S, Kaur H, Kerr J, Khajuria H, Khan A, Khatab K, Kheirallah K, Kim K, Kim M, Shivakumar S, Kolahi A, Koohestani H, Krishna V, Kugbey N, Kulimbet M, Kumar G, Kumar M, Kundu S, Kytö V, Landires I, Le N, Lee D, Lee W, Lee Y, Lim S, Lin J, Liu R, López-Gil J, Lucchetti G, Feei Z, Maled V, Malhotra K, Malik A, Marconi A, Martinez-Piedra R, Marzo R, Mathangasinghe Y, Maulik P, Meles H, Menezes R, Meretoja T, Mestrovic T, Michalek I, Miller T, Mirza M, Misganaw A, Mittal C, Mohamed A, Mohamed N, Mohammadian-Hafshejani A, Mokdad A, Molinaro S, Monasta L, Ghalibaf A, Morrison S, Motappa R, Mughal F, Mulita F, Munkhsaikhan Y, Murray C, Muthu S, Myung W, Nafei A, Naghavi P, Naik G, Naik G, Natto Z, Naveed M, Navid S, Nayak B, Nazri-Panjaki A, Netsere H, Neupane S, Nguyen H, Nguyen N, Nguyen P, Phuong The Nguyen, Nguyen V, Nikoobar A, Noguer I, Nomura S, Nri-Ezedi C, Nuñez-Samudio V, Nzoputam O, Oancea B, Oduro M, Oh I, Okeke S, Oluwafemi Y, Ong S, Ordak M, Orpana H, Ortiz-Prado E, Osuagwu U, Padron-Monedero A, Padubidri J, Palma-Alvarez R, Pandey A, Pandey A, Pantazopoulos I, Park S, Park S, Pashaei A, Patel J, Pawar S, Peprah, Peres M, Petcu I, Philip A, Phillips M, Piracha Z, Pradhan J, Prates E, Pribadi D, Puvvula J, Qattea I, Qian G, Radhakrishnan V, Raghav P, Rahimibarghani S, Rahimi-Movaghar A, Rahimi-Movaghar V, Rahman M, Rahman M, Rahman M, Rahmanian M, Rajpoot P, Ramadan M, Ramasamy S, Rani S, Rao M, Rao S, Rashidi M, Rastogi P, Rathish D, Rawaf D, Reifels L, Rezaeian M, Rhee T, Rickard J, Roever L, Rony M, Chandan S, Saddik B, Sadeghian F, Saeb M, Saeed U, Moghaddam S, Safari M, Sagoe D, Sharif-Askari N, Sahoo P, Sahoo S, Salamati P, Salihu D, Salimi S, Salum G, Sameen S, Samy A, Santric-Milicevic M, Sarkar C, Sarode G, Sarode S, Sathian B, Schumacher A, Šekerija M, Semreen M, Sepanlou S, Shafie M, Shahid S, Shaikh A, Shaikh M, Sharifan A, Rad J, Sharma A, Sharma V, Sheikhi R, Shetty M, Shetty P, Shetty P, Shivarov V, Shool S, Singh P, Singh P, Singh S, Socea B, Stein D, Stein M, Sun J, Swain C, Szarpak L, Y S, Tabatabaei S, Tabche C, Tareke M, Temsah M, Thum C, Tiruye T, Tovani-Palone M, Tran N, Tran T, Duc N, Tromans S, Truyen T, Tsegay G, Tumurkhuu M, Vahdati S, Vaithinathan A, Valdez P, Vasankari T, Veroux M, Verras G, Vinayak M, Vos T, Walde M, Wang Y, Ward J, Wickramasinghe N, Wojewodzic M, Yesodharan R, Yiğit A, Yin D, Yip P, Yon D, Yonemoto N, Yu C, Zare I, Zeariya M, Zhang H, Zhong C, Zhu B, Zhumagaliuly A, Naghavi M. Global, regional, and national burden of suicide, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet Public Health 2025, 10: e189-e202. PMID: 39986290, PMCID: PMC11876099, DOI: 10.1016/s2468-2667(25)00006-4.Peer-Reviewed Original ResearchConceptsAge-standardised mortality ratesBurden of suicideRates of suicideIncidence of suicide attemptsGlobal burdenHighest age-standardised rateGlobal Burden of Disease StudyBurden of Disease StudyGlobal Burden of DiseaseSouthern sub-Saharan AfricaMortality rateAge-standardised ratesSub-Saharan AfricaPublic health frameworkRisk Factors StudyReduce suicide mortalityBurden of diseasePopulation mortality ratesMortality surveillanceCentral sub-Saharan AfricaVerbal autopsySuicide attemptsSuicide burdenVital registrationHealth frameworkThe Factor Structure and Validity of the Psychopathy Checklist‐Short Version When Used With Autistic Psychiatric Inpatients
Maguire K, Barnoux M, Collins J, Melvin C, Inkson I, Alexander R, Devapriam J, Duggan C, Shepstone L, Staufenburg E, Thompson P, Turner D, Viding E, Langdon P. The Factor Structure and Validity of the Psychopathy Checklist‐Short Version When Used With Autistic Psychiatric Inpatients. Autism Research 2025, 18: 614-631. PMID: 39963077, PMCID: PMC11928917, DOI: 10.1002/aur.70004.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAntisocial Personality DisorderAutistic DisorderChecklistEnglandFactor Analysis, StatisticalFemaleHospitals, PsychiatricHumansInpatientsIntellectual DisabilityMaleMiddle AgedPersonality TestsPrisonersProspective StudiesPsychometricsRegression AnalysisReproducibility of ResultsROC CurveWalesYoung AdultConceptsMental Health ActPCL:SVPersonality disorder diagnosisForensic historyHealth ActIntellectual disabilityAutistic adultsDisorder diagnosisHistory of violent offendingPCL:SV scoresMeasures of psychopathyInpatient psychiatric hospitalizationPart IIInpatient psychiatric carePCL-SVCriminal offendingHCR-20Violent offendersSV scoresPsychiatric inpatientsFactor structurePsychiatric hospitalPsychopathyPsychiatric careLesser securityExploring sociodemographic disparities in diagnostic problems and mistakes in the quest for diagnostic equity: insights from a national survey of patient experiences
McDonald K, Gleason K, Grob R, Yuan C, Dhingra I, Evered J, Warne E, Schlesinger M. Exploring sociodemographic disparities in diagnostic problems and mistakes in the quest for diagnostic equity: insights from a national survey of patient experiences. Frontiers In Public Health 2025, 13: 1444005. PMID: 40017549, PMCID: PMC11865055, DOI: 10.3389/fpubh.2025.1444005.Peer-Reviewed Original ResearchConceptsNational survey of patient experiencesSurvey of patient experienceU.S. population-based surveysPopulation-based surveyLower household incomeNationally representative sampleWorking full-timePatient experienceSociodemographic disparitiesSociodemographic characteristicsSociodemographic predictorsSociodemographic groupsEpidemiological researchDiagnostic disparitiesRepresentative sampleU.S. populationHousehold incomeMultivariate regression analysisDiagnostic experienceNational surveyAnalysis of dataOutcome estimatesYounger ageCis femaleFull-timeIdentification and comprehensive characterization of moral disapproval and behavioral dysregulation-based pornography-use profiles across 42 countries.
Bőthe B, Tóth-Király I, Popova N, Nagy L, Koós M, Demetrovics Z, Potenza M, Kraus S, Ballester-Arnal R, Batthyány D, Bergeron S, Billieux J, Briken P, Burkauskas J, Cárdenas-López G, Carvalho J, Castro-Calvo J, Chen L, Ciocca G, Corazza O, Csako R, Czakó A, Fernandez D, Fernandez E, Fujiwara H, Fuss J, Gabrhelík R, Gewirtz-Meydan A, Gjoneska B, Gola M, Hashim H, Islam M, Ismail M, Jiménez-Martínez M, Jurin T, Kalina O, Klein V, Költő A, Lee C, Lee S, Lewczuk K, Lin C, Lochner C, López-Alvarado S, Lukavská K, Mayta-Tristán P, Miller D, Orosová O, Orosz G, _ _, Ponce F, Quintana G, Quintero Garzola G, Ramos-Diaz J, Rigaud K, Rousseau A, Scanavino M, Schulmeyer M, Sharan P, Shibata M, Shoib S, Sigre-Leirós V, Sniewski L, Spasovski O, Steibliene V, Stein D, Štulhofer A, Ünsal B, Vaillancourt-Morel M, Van Hout M, Grubbs J. Identification and comprehensive characterization of moral disapproval and behavioral dysregulation-based pornography-use profiles across 42 countries. Journal Of Behavioral Addictions 2025, 14: 131-154. PMID: 39945767, DOI: 10.1556/2006.2024.00054.Peer-Reviewed Original Research“Ice” flavor elements in E-cigarette images: Influence on liking and intention to use among youth who are at risk of E-cigarette use
Li W, Davis D, Buta E, Gueorguieva R, Khan N, Green B, Garrison K, Krishnan-Sarin S. “Ice” flavor elements in E-cigarette images: Influence on liking and intention to use among youth who are at risk of E-cigarette use. Drug And Alcohol Dependence 2025, 269: 112600. PMID: 39970576, DOI: 10.1016/j.drugalcdep.2025.112600.Peer-Reviewed Original Research
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