2025
Craniosynostosis among children with X-linked hypophosphatemia: A systematic review and meta-analysis
Fisch S, Tudor A, Benchekroun E, Landsberg W, Feldstein N, Lamb M, Carpenter T, Rundle A, Jacobson J, Neugut A, Freedberg D. Craniosynostosis among children with X-linked hypophosphatemia: A systematic review and meta-analysis. Bone 2025, 196: 117488. PMID: 40220947, DOI: 10.1016/j.bone.2025.117488.Peer-Reviewed Original ResearchX-linked hypophosphatemiaPrevalence of craniosynostosisPooled prevalenceSystematic reviewMeta-analysisRandom-effects modelWeb of SciencePediatric populationSkull abnormalitiesCohort studyImpaired phosphate reabsorptionElevated FGF23 levelsPrevalenceFemale predominanceCase seriesFGF23 levelsPhosphate reabsorptionGene variantsChildrenIncreased vigilanceCraniosynostosisAbnormal bone growthGenetic disordersHypophosphatemiaAbnormalitiesThe case-only design is a powerful approach to detect interactions but should be used with caution
Dong R, Wang G, DeWan A, Leal S. The case-only design is a powerful approach to detect interactions but should be used with caution. BMC Genomics 2025, 26: 222. PMID: 40050722, PMCID: PMC11884093, DOI: 10.1186/s12864-025-11318-1.Peer-Reviewed Original ResearchConceptsCase-only designRare disease assumptionType I error rateIncreased type I error ratesDisease prevalenceInvestigated type I errorComplex traitsInteraction termsInteraction effect sizesDetect interactionsCase-control designControlled type I error ratesSample sizeHigher disease prevalenceEffect sizeLow disease prevalenceType I errorPrevalenceExposure frequencyGenesType I andDesign studyEnvironmental factorsTraitsEnvironment interactionCardiovascular Event Prevalence in Type 1 Versus Type 2 Diabetes: Veradigm Metabolic Registry Insights
Goldsweig A, Knee A, Tak H, Desai N, Bradley S, Lotfi A, Spertus J, Goldsweig B. Cardiovascular Event Prevalence in Type 1 Versus Type 2 Diabetes: Veradigm Metabolic Registry Insights. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102502. DOI: 10.1016/j.jscai.2024.102502.Peer-Reviewed Original ResearchIncident cardiovascular eventsPrevalence ratiosDiabetes mellitus type 1Risk of incident cardiovascular eventsCardiovascular diseaseCardiovascular eventsPrimary carePercutaneous coronary interventionMyocardial infarctionType 2 diabetesOutpatient facilitiesEvent prevalenceLimb ischemiaCoronary interventionAge categoriesStudy populationDM2 patientsRisk factorsHemoglobin A1cCarePrevalencePeripheral revascularizationInterventionComorbiditiesDM2Prevalence of Moral Injury in Nationally Representative Samples of Combat Veterans, Healthcare Workers, and First Responders
Maguen S, Griffin B, Pietrzak R, McLean C, Hamblen J, Norman S. Prevalence of Moral Injury in Nationally Representative Samples of Combat Veterans, Healthcare Workers, and First Responders. Journal Of General Internal Medicine 2025, 1-7. PMID: 39881119, DOI: 10.1007/s11606-024-09337-x.Peer-Reviewed Original ResearchNationally representative sampleHealthcare workersRepresentative sampleMoral injuryDesignCross-sectional surveyPrevalence of moral injuryFirst respondersExposure to PMIEsMoral injury symptomsCombat veteransHigh-risk populationHigh-risk groupInjury eventsInjury exposureHealthcareVeteransWell-beingOccupational differencesRespondentsPMIEsPrevalenceWorkersComplex decisionsClinicInjuryTuberculosis and people who use drugs: why focus on this overlooked population is important and why adapted interventions are necessary
D'Ottavi M, Godfrey-Faussett P, Merle C, Sofonea M, Laureillard D, Vickerman P, Molès J, Altice F, Van de Perre P, Stone J, Nagot N. Tuberculosis and people who use drugs: why focus on this overlooked population is important and why adapted interventions are necessary. The Lancet Global Health 2025, 13: e593-e598. PMID: 39862874, DOI: 10.1016/s2214-109x(24)00481-9.Peer-Reviewed Original ResearchConceptsReduce health inequalitiesCommunity-based approachActive case findingNational Tuberculosis ProgrammeHealth inequalitiesTargeted interventionsTuberculosis interventionsCase findingTreatment adherenceGeneral populationTuberculosis ProgrammeMarginalised populationsHIV fieldInterventionPrevalence of tuberculosisTuberculosis burdenPopulation levelTuberculosis transmissionHigher incidencePeoplePopulationAdherenceHIVPrevalenceLinkageIncidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study
Vernon S, Zheng T, Do H, Marconi V, Jason L, Singer N, Natelson B, Sherif Z, Bonilla H, Taylor E, Mullington J, Ashktorab H, Laiyemo A, Brim H, Patterson T, Akintonwa T, Sekar A, Peluso M, Maniar N, Bateman L, Horwitz L, Hess R. Incidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study. Journal Of General Internal Medicine 2025, 1-10. PMID: 39804551, DOI: 10.1007/s11606-024-09290-9.Peer-Reviewed Original ResearchSARS-CoV-2 infectionLongitudinal observational cohort studyClinical diagnostic criteriaSelf-reported symptomsResultsThe incidence rateBackgroundMyalgic encephalomyelitis/chronic fatigue syndromeTiming of SARS-CoV-2 infectionPost-exertional malaiseObservational cohort studyUninfected participantsPost-acuteSARS-CoV-2Diagnostic criteriaCohort studyHazard ratioStudy visitsFatigue syndromeParticipantsEnhanced recoveryME/CFS symptomsLong COVIDMyalgic encephalomyelitisDays of infectionPrevalenceInfected participantsmosGILT antibodies interfere with Plasmodium sporogony in Anopheles gambiae
Dolan B, Correa Gaviria T, Dong Y, Cresswell P, Dimopoulos G, Chuang Y, Fikrig E. mosGILT antibodies interfere with Plasmodium sporogony in Anopheles gambiae. Nature Communications 2025, 16: 592. PMID: 39799117, PMCID: PMC11724845, DOI: 10.1038/s41467-025-55902-1.Peer-Reviewed Original ResearchConceptsCausative agent of malariaTransmission-blocking vaccinesMurine infection modelPlasmodium life cycleAgent of malariaGamma-interferon-inducible lysosomal thiol reductaseP. falciparumInfection modelAnopheles gambiaeMosquito midgutPlasmodiumLysosomal thiol reductaseCausative agentAntibodiesOocyst stageInfection prevalenceThiol reductaseMalariaGambiaInfectionMosquitoesPrevalenceVaccineA Meta-analysis of the Prevalence of Food Insecurity Among People Experiencing Housing Insecurity and Homelessness in the United States.
Jackson C, Hart C, Uribe-Lacy C, Yang P, Tsai J. A Meta-analysis of the Prevalence of Food Insecurity Among People Experiencing Housing Insecurity and Homelessness in the United States. Public Health Reports 2025, 333549241305349. PMID: 39760409, PMCID: PMC11705288, DOI: 10.1177/00333549241305349.Peer-Reviewed Original ResearchPrevalence of food insecurityOdds of food insecurityFood insecurityAssociated with increased odds of food insecurityHousing insecurityFactors associated with food insecurityMental health conditionsAssociated with decreased oddsAssociated with increased oddsMeta-analysisUnited StatesHealth conditionsUnique articlesUS populationMultisectoral coordinationSystematic reviewExperience symptomsComprehensive searchAcademic databasesPrevalenceInsecurityInstitutional supportHIHPeopleHomelessness
2024
Measurement and Prevalence of Aggression
Iennaco J, Molle E, Lauvrud C, Palmstierna T, Nijman H, Almvik R. Measurement and Prevalence of Aggression. 2024, 93-123. DOI: 10.1007/978-3-031-61224-4_5.Peer-Reviewed Original ResearchQuality of carePatient safetyActivity programmeHealthcare workplaceHealthcare settingsPatient carePsychiatric settingsOverview of scalesImpact patientsTherapeutic relationshipClinical environmentCoercive interventionsPrevalence of aggressionClinical settingCareHealthcareSeverity of violenceHigher ratesPrevalenceViolenceCaregiversSetsPatientsComplex issuesInterventionCharacteristics of autoantibody-positive individuals without high-risk HLA-DR4-DQ8 or HLA-DR3-DQ2 haplotypes
Redondo M, Cuthbertson D, Steck A, Herold K, Oram R, Atkinson M, Brusko T, Parikh H, Krischer J, Onengut-Gumuscu S, Rich S, Sosenko J. Characteristics of autoantibody-positive individuals without high-risk HLA-DR4-DQ8 or HLA-DR3-DQ2 haplotypes. Diabetologia 2024, 68: 588-601. PMID: 39670998, PMCID: PMC11832693, DOI: 10.1007/s00125-024-06338-7.Peer-Reviewed Original ResearchHLA-DR4-DQ8HLA-DR3-DQ2High-risk HLA haplotypesType 1 diabetesAutoantibody-positive individualsHLA haplotypesHLA-DR3-DQ2 haplotypeClinical type 1 diabetesType 1 diabetes pathogenesisPrevalence of autoantibodiesPrevalence of overweight/obesityIslet autoantibody-positive individualsAutoantibody-positive relativesHLA-DRB1Metabolic markersC-peptideIA-2DR3/DR4Aetiological heterogeneityYounger ageNon-Hispanic participantsPhenotypic differencesAssociated with phenotypic differencesPrevalenceRelatives of individualsA bibliometric analysis of inflammatory bowel disease research in the Arab world.
AlMuhaidib S, Bzeizi K, AlAmeel T, Mosli M, Khoja B, Barakeh D, Alomaim W, Alqahtani S, Al-Bawardy B. A bibliometric analysis of inflammatory bowel disease research in the Arab world. Saudi Journal Of Gastroenterology 2024 PMID: 39660608, DOI: 10.4103/sjg.sjg_303_24.Peer-Reviewed Original ResearchCitation impactPublication countsBibliometric analysisResearch outputPrevalence of inflammatory bowel diseaseInflammatory bowel diseaseClarivate AnalyticsIncidence rateResearch impactInstitute for Health MetricsCitationsIncidence trendsHealth metricsIBD incidenceRising prevalenceArab countriesGlobal ratingImproving research impactIBD researchInflammatory bowel disease researchSpearman correlationPrevalenceClarivateMetricsOutputPsychological stress, cardiovascular disease and somatic pain in asylum seekers: a retrospective cross-sectional study
Lurie J, Pietz H, Hatef C, Taki F, Lee A, Virk S, Oren T, Gbekie C, Milewski A, Boyer R, Kaur G. Psychological stress, cardiovascular disease and somatic pain in asylum seekers: a retrospective cross-sectional study. Nature Mental Health 2024, 2: 1442-1450. DOI: 10.1038/s44220-024-00312-3.Peer-Reviewed Original ResearchSymptoms of psychological stressSomatic painCross-sectional studyCardiovascular diseasePsychological stressRetrospective cross-sectional studyStress symptomsCardiovascular disease symptomsChest painPain symptomsHealth outcomesCVD symptomsPainRisk factorsStroke symptomsMedical evaluationSymptomsAsylum seekersComorbidityPrevalenceUnderstanding the impact of covariates on the classification of implementation units for soil-transmitted helminths control: a case study from Kenya
Puranik A, Diggle P, Odiere M, Gass K, Kepha S, Okoyo C, Mwandawiro C, Wakesho F, Omondi W, Sultani H, Giorgi E. Understanding the impact of covariates on the classification of implementation units for soil-transmitted helminths control: a case study from Kenya. BMC Medical Research Methodology 2024, 24: 294. PMID: 39614175, PMCID: PMC11606136, DOI: 10.1186/s12874-024-02420-1.Peer-Reviewed Original ResearchConceptsPredictive inferenceRemotely sensed covariatesSimulation studyModel-based geostatisticsGeostatistical modelImpact of covariatesSpatially referenced covariatesSample sizeModern statistical methodsModel-based geostatistical methodsCross-sectional surveyCovariatesReduced sample sizeClassification of areasPrevalence predictionsInferenceDisease riskMethodsThis studyPrevalenceSub-countyPrevalence levelsElectronic nicotine delivery system flavors, devices, and brands used by adults in the United States who smoke and formerly smoked in 2022: Findings from the United States International Tobacco Control Four Country Smoking and Vaping Survey
Gravely S, Smith T, Toll B, Ashley D, Driezen P, Levy D, Quah A, Fong G, Cummings K. Electronic nicotine delivery system flavors, devices, and brands used by adults in the United States who smoke and formerly smoked in 2022: Findings from the United States International Tobacco Control Four Country Smoking and Vaping Survey. Preventive Medicine Reports 2024, 47: 102905. PMID: 39498210, PMCID: PMC11533091, DOI: 10.1016/j.pmedr.2024.102905.Peer-Reviewed Original ResearchElectronic nicotine delivery systemsUS adultsInternational Tobacco Control Four Country SmokingVaping SurveySmoking cigarettesHighest proportion of adultsNationally representative sampleSignificantly higher proportion of adultsProportion of adultsNicotine delivery systemsQuit smokingCountry SmokingRepresentative sampleSignificantly higher proportionENDS flavorsSmokingAdultsIce flavoursWeight dataVapingCigarettePrevalenceUnited StatesSurveyTank devicesSigns of Potential Androgen Excess Across the Lifespan in a US-based Digital Cohort Study
Wolf A, Wang Z, Onnela J, Baird D, Jukic A, Curry C, Fischer-Colbrie T, Williams M, Hauser R, Coull B, Mahalingaiah S. Signs of Potential Androgen Excess Across the Lifespan in a US-based Digital Cohort Study. The Journal Of Clinical Endocrinology & Metabolism 2024, dgae674. PMID: 39388314, DOI: 10.1210/clinem/dgae674.Peer-Reviewed Original Research8714 Impact of Adrenalectomy Versus Conservative Therapy On Frailty In Mild Autonomous Cortisol Secretion: A Prospective Multi-Center Cohort Study
Bassiony M, Dogra P, Šambula L, Saini J, Ambroziak U, Kastelan D, Bancos I. 8714 Impact of Adrenalectomy Versus Conservative Therapy On Frailty In Mild Autonomous Cortisol Secretion: A Prospective Multi-Center Cohort Study. Journal Of The Endocrine Society 2024, 8: bvae163.213. PMCID: PMC11454724, DOI: 10.1210/jendso/bvae163.213.Peer-Reviewed Original ResearchNonfunctioning adrenal adenomasAutonomous cortisol secretionPost-dexamethasone cortisolTreated patientsFrailty indexCortisol secretionMulti-center cohort studyCompared to patientsImpact of adrenalectomyFrailty prevalenceAdrenal adenomaPost-adrenalectomyConservative therapyMedian ageCohort studyAdrenalectomyPatientsConservative managementFrailty assessmentAdverse health outcomesPrevalenceBaselineBaseline FIHealth outcomesImproved FIAgeism in the Mental Health Setting
Dix E, Van Dyck L, Adeyemo S, Blazek M, Lehmann S, Singh E, Wilkins K. Ageism in the Mental Health Setting. Current Psychiatry Reports 2024, 26: 583-590. PMID: 39278983, DOI: 10.1007/s11920-024-01531-2.Peer-Reviewed Original ResearchMental health settingsMental health care settingsHealth care settingsHealth settingsCare settingsOlder adultsCombat ageismLong-term careAge-friendly practicesHealthcare traineesHealthcare providersPsychosocial consequencesHealthcare systemPublic policy strategiesHealthcareAgeismReviewThis paperAdultsSetsCareProvidersPolicy strategiesTraineesPrevalenceMentalCommunication trends over time in new-onset refractory status epilepticus (NORSE): Interim analysis from the NORSE/FIRES Family Registry
Kazazian K, Gaspard N, Hirsch L, Kellogg M, Hocker S, Wong N, Farias-Moeller R, Eschbach K, Gofton T. Communication trends over time in new-onset refractory status epilepticus (NORSE): Interim analysis from the NORSE/FIRES Family Registry. Epilepsy & Behavior 2024, 160: 110023. PMID: 39241640, DOI: 10.1016/j.yebeh.2024.110023.Peer-Reviewed Original ResearchPalliative care servicesFamily RegistryCare servicesImprove overall carePrognostic conversationsAcute hospitalsOverall careEpidemiological informationConsensus definitionPhysician-patient-family relationshipRegistryNORSE/FIRESMinority of patientsPrognostic informationSatisfactionFamilySystematic effortRecovery processServicesCarePatientsHospitalPrevalenceQualityEpilepsy syndromesSex Differences in Hypertension and Its Management Throughout Life
Yeo W, Abraham R, Surapaneni A, Schlosser P, Ballew S, Ozkan B, Flaherty C, Yu B, Bonventre J, Parikh C, Kimmel P, Vasan R, Coresh J, Grams M. Sex Differences in Hypertension and Its Management Throughout Life. Hypertension 2024, 81: 2263-2274. PMID: 39229711, PMCID: PMC11483212, DOI: 10.1161/hypertensionaha.124.22980.Peer-Reviewed Original ResearchPrevalence of hypertensionUncontrolled hypertensionChronic kidney disease progressionPrevalence of uncontrolled hypertensionKidney disease progressionBody mass indexClasses of medicationsSex differencesEstimate sex differencesCoronary heart diseaseHeart failureMass indexAntihypertensive medicationsDisease progressionStudy visitsAtherosclerosis RiskHypertensionHigh riskHypertensive individualsHeart diseaseLife courseCommunity studiesPrevalenceMedicationLower Microscopy Sensitivity with Decreasing Malaria Prevalence in the Urban Amazon Region, Brazil, 2018–2021 - Volume 30, Number 9—September 2024 - Emerging Infectious Diseases journal - CDC
Rodrigues P, Johansen I, Ladeia W, Esquivel F, Corder R, Tonini J, Calil P, Fernandes A, Fontoura P, Cavasini C, Vinetz J, Castro M, Ferreira M, . Lower Microscopy Sensitivity with Decreasing Malaria Prevalence in the Urban Amazon Region, Brazil, 2018–2021 - Volume 30, Number 9—September 2024 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2024, 30: 1884-1894. PMID: 39174028, PMCID: PMC11346994, DOI: 10.3201/eid3009.240378.Peer-Reviewed Original ResearchConceptsEffectiveness of malaria controlDecreasing malaria prevalenceEpidemiology of malariaPoint-of-care microscopyThreshold of microscopyPlasmodium vivaxMalaria prevalenceMalarial infectionMalaria controlMalaria transmissionP. falciparumMicroscopy sensitivityParasite densityAsymptomatic infectionRoutine surveillanceMalariaPrevalence surveyInfectionPrevalenceParasite genotypesTransmission hotspotsElimination strategiesRural residentsMolecular methodsCDC
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