2025
Functional Outcomes for Patients With Congenital Anorectal Malformations: A Systematic Review and Evidence-based Guideline From the APSA Outcomes and Evidence Based Practice Committee
Rialon K, Smith C, Rentea R, Acker S, Baird R, Beres A, Chang H, Christison-Lagay E, Diesen D, Englum B, Gonzalez K, Gulack B, Ham P, Huerta C, Kulaylat A, Levene T, Lucas D, Mansfield S, Pennell C, Ricca R, Sulkowski J, Tashiro J, Wakeman D, Yousef Y, Kelley-Quon L, Kawaguchi A, Committee A. Functional Outcomes for Patients With Congenital Anorectal Malformations: A Systematic Review and Evidence-based Guideline From the APSA Outcomes and Evidence Based Practice Committee. Journal Of Pediatric Surgery 2025, 60: 162243. PMID: 40023107, DOI: 10.1016/j.jpedsurg.2025.162243.Peer-Reviewed Original ResearchQuality of lifeSystematic reviewStructured care planFunctional outcomesAnorectal malformationsOptimal patient counselingComplex patient populationTransitional careLevel of evidenceCare planningImprove carePatient transitionsPsychosocial issuesAdult careAmerican Pediatric Surgical Association OutcomesPsychosocial functioningCareConstipation ratePractice CommitteeAnorectal malformation patientsAssociated outcomesCongenital anorectal malformationsMulti-institutional registryPatient counselingLong-term outcomesRealigning diabetes regimens in older adults: a 4S Pathway to guide simplification and deprescribing strategies
Munshi M, Kahkoska A, Neumiller J, Alexopoulos A, Allen N, Cukierman-Yaffe T, Huang E, Lee S, Lipska K, McCarthy L, Meneilly G, Pandya N, Pratley R, Rodriguez-Mañas L, Sinclair A, Sy S, Toschi E, Weinstock R. Realigning diabetes regimens in older adults: a 4S Pathway to guide simplification and deprescribing strategies. The Lancet Diabetes & Endocrinology 2025 PMID: 39978368, DOI: 10.1016/s2213-8587(24)00372-3.Peer-Reviewed Original ResearchOlder adultsCare of older individualsHigh-risk medicationsTreating older peopleClinical practice gapsInterfere with patients' abilityReduce medication burdenDiabetes treatment regimensImprove carePatient's current needsSelf-careDe-prescribingDiabetes guidelinesDeprescribing strategiesSimplification of regimensOlder peoplePractice gapType 2 diabetesDeprescribingPatient's abilityMultiple medical comorbiditiesDiabetes regimensOlder individualsDiabetes SocietyMedical burdenMeasurement properties of instruments to assess insight in psychosis: A systematic review protocol
Hazan H, Funaro M, Srihari V. Measurement properties of instruments to assess insight in psychosis: A systematic review protocol. PLOS ONE 2025, 20: e0316447. PMID: 39854417, PMCID: PMC11759350, DOI: 10.1371/journal.pone.0316447.Peer-Reviewed Original ResearchConceptsMeasurement properties of instrumentsProperties of instrumentsSystematic reviewCOSMIN Risk of Bias checklistRisk of Bias checklistMeasurement propertiesMeasure methodological qualityMeta-Analysis ProtocolsSynthesize current evidenceSystematic review protocolPreferred Reporting ItemsClinical practicePeer-reviewed journalsStrength of evidenceSemi-structured interviewsBias checklistImprove careMental illnessMethodological qualityReporting ItemsPatient awarenessPRISMA-PReview protocolGRADE approachSelf-reportQualitative analysis of pain impact in adult patients with X-linked hypophosphatemia
Nishime N, Theriault C, Feinn R, Macica C. Qualitative analysis of pain impact in adult patients with X-linked hypophosphatemia. JBMR Plus 2025, 9: ziaf012. PMID: 40060917, PMCID: PMC11890110, DOI: 10.1093/jbmrpl/ziaf012.Peer-Reviewed Original ResearchHealth-related quality of lifeQuality of lifeDomains of health-related quality of lifePain self-management interventionShort Form Survey InstrumentX-linked hypophosphatemiaEffective pain management strategiesSelf-management interventionsHealthcare providers' lackHealth-related qualityPain management strategiesExperiences of adultsImprove quality of lifeAge-adjusted differencesSemi-structured interviewsPhysical inactivityProviders' lackQualitative analysis of interviewsHealthcare accessPhysical functionImprove carePhysical therapyEmotional burdenSF-36Healthcare servicesThe association between clinical trial participation, drug costs, and performance in the Oncology Care Model
Canavan M, Westvold S, Csik V, Franks J, Rocque G, Gross C, Adelson K. The association between clinical trial participation, drug costs, and performance in the Oncology Care Model. Journal Of The National Cancer Institute 2025, djaf008. PMID: 39842859, DOI: 10.1093/jnci/djaf008.Peer-Reviewed Original ResearchOncology Care ModelCare modelValue-based payment programsMedicare alternative payment modelsAlternative payment modelsRandom-effects meta-analysisImpact of clinical trialsClinical trial participationCT episodesEffects meta-analysisAcademic oncology practicesImprove careClinical trialsPatient complexityPayment modelsPayment programsMedicare costsTrial participantsOncology practiceCancer CenterMeta-analysisMedicareDrug costsParticipantsOncologyVascular Quality Initiative Assessment of Compliance with Society for Vascular Surgery Practice Guidelines for the Endovascular Management of Claudication
Iannuzzi J, Animilli S, Simons J, Tonnessen B, Koleilat I, Indes J, Conte M, Eldrup-Jorgensen J. Vascular Quality Initiative Assessment of Compliance with Society for Vascular Surgery Practice Guidelines for the Endovascular Management of Claudication. Journal Of Vascular Surgery 2025 PMID: 39824263, DOI: 10.1016/j.jvs.2025.01.007.Peer-Reviewed Original ResearchManagement of claudicationHospital-level variationGuideline releaseIncreased odds of smokingArea Deprivation IndexUptake of guidelinesChanges to clinical practiceOdds of smokingMedical managementSociety for Vascular SurgeryCases of claudicationHigh-grade recommendationsAlign careDeprivation indexImprove carePreoperative smoking cessationSmoking cessationMedical therapySocial deprivationDecreased oddsIncreased oddsSecondary analysisStent usePost-procedural recommendationsPractice guidelines
2024
Frailty integration in medical specialties: Current evidence and suggested strategies from the Clin‐STAR frailty interest group
Singh N, Faye A, Abidi M, Grant S, DuMontier C, Iyer A, Jain N, Kochar B, Lieber S, Litke R, Loewenthal J, Masters M, Nanna M, Robison R, Sattui S, Sheshadri A, Shi S, Sherman A, Walston J, Wysham K, Orkaby A. Frailty integration in medical specialties: Current evidence and suggested strategies from the Clin‐STAR frailty interest group. Journal Of The American Geriatrics Society 2024 PMID: 39584362, DOI: 10.1111/jgs.19268.Peer-Reviewed Original ResearchRecommendations for Clinicians, Technologists, and Healthcare Organizations on the Use of Generative Artificial Intelligence in Medicine: A Position Statement from the Society of General Internal Medicine
Crowe B, Shah S, Teng D, Ma S, DeCamp M, Rosenberg E, Rodriguez J, Collins B, Huber K, Karches K, Zucker S, Kim E, Rotenstein L, Rodman A, Jones D, Richman I, Henry T, Somlo D, Pitts S, Chen J, Mishuris R. Recommendations for Clinicians, Technologists, and Healthcare Organizations on the Use of Generative Artificial Intelligence in Medicine: A Position Statement from the Society of General Internal Medicine. Journal Of General Internal Medicine 2024, 40: 694-702. PMID: 39531100, PMCID: PMC11861482, DOI: 10.1007/s11606-024-09102-0.Peer-Reviewed Original ResearchSociety of General Internal MedicineGeneral internal medicineHealthcare organizationsClinical workforceInternal medicinePatient-physician relationshipDomain of medical practiceGenerative AIPractice of medicineClinical decision-makingImprove careGenerative artificial intelligenceHealthcareTherapeutic relationshipPosition statementMedical practiceArtificial intelligenceDomain of healthcareLong-term impactCliniciansBiomedical advancesEquity considerationsWorkforceMedicineUnintended consequencesImproving hospital-based opioid substitution therapy (iHOST): protocol for a mixed-methods evaluation
Lewer D, Brown M, Burns A, Eastwood N, Gittins R, Holland A, Hope V, Ko A, Lewthwaite P, Morris A, Noctor A, Preston A, Scott J, Smith E, Sweeney S, Tilouche N, Wickremsinhe M, Harris M. Improving hospital-based opioid substitution therapy (iHOST): protocol for a mixed-methods evaluation. NIHR Open Research 2024, 4: 10. PMID: 39568556, PMCID: PMC11576563, DOI: 10.3310/nihropenres.13534.2.Peer-Reviewed Original ResearchOpioid substitution therapyProcess evaluationPatient-directed dischargeAssociated with improved healthQualitative process evaluationHospital-based servicesHealth research projectsMixed-methods evaluationQuasi-experimental quantitative studyDifference-in-differences analysisMixed-methods studyOnline training moduleSubstitution therapyAdmitted to hospitalControl hospitalsAcute hospitalsImprove careOpioid withdrawalHospital cliniciansEmergency readmissionIllicit opioidsHospital staffQuantitative studyFocus groupsClinical guidelinesTrends in Revision Facial Feminization Surgery
Ihnat J, Hu K, Wood S, Sutherland R, Allam O, Parikh N, Alperovich M. Trends in Revision Facial Feminization Surgery. Journal Of Craniofacial Surgery 2024, 36: 769-772. PMID: 39325077, DOI: 10.1097/scs.0000000000010693.Peer-Reviewed Original ResearchFacial feminization surgeryGender-affirming surgeryFeminization surgeryFacial feminization surgery proceduresFacial feminization surgery patientsEnhance surgical outcomesHormone therapySurgical outcomesSurgical approachChart reviewLower BMIManual chart reviewPatient factorsSurgerySmoking statusPatientsTGNB patientsGender-affirming proceduresOlder ageBMIDiagnosis of transsexualismAssociated with differencesOutcomesImprove careAgeClinical Genetic Testing in Nephrology: Core Curriculum 2024
Aron A, Dahl N. Clinical Genetic Testing in Nephrology: Core Curriculum 2024. American Journal Of Kidney Diseases 2024, 84: 632-645. PMID: 39340488, DOI: 10.1053/j.ajkd.2024.05.011.Peer-Reviewed Original ResearchClinical genetic testingGenetic testingRoutine diagnostic workup of patientsKidney diseaseDiagnostic workup of patientsDiagnostic yield of testingRoutine diagnostic workupWorkup of patientsRoutine nephrology careYield of testingGenetic resultsImprove careCore curriculumReduce barriersDiagnostic odysseyExtrarenal manifestationsDiagnostic yieldMonogenic etiologyPatient selectionReduce anxietyPatient populationNephrology careTreatment planningFamily planningSecondary findingsTrustworthy and ethical AI-enabled cardiovascular care: a rapid review
Mooghali M, Stroud A, Yoo D, Barry B, Grimshaw A, Ross J, Zhu X, Miller J. Trustworthy and ethical AI-enabled cardiovascular care: a rapid review. BMC Medical Informatics And Decision Making 2024, 24: 247. PMID: 39232725, PMCID: PMC11373417, DOI: 10.1186/s12911-024-02653-6.Peer-Reviewed Original ResearchConceptsHealthcare provider perspectiveRisk of patient harmCardiovascular careProvider perspectiveAI-based medical devicesPatient harmLoss of patient autonomyLack of robust evidenceTrust barriersHealthcare inequalitiesImprove careHealthcare providersCitation chasingPerceived lack of transparencyHealthcare existPatient careEthical concernsIntegration of AIPatient autonomyPatient interestLiterature reviewPerceived lackPractice guidelinesCareStudy designProviders’ knowledge and perception of xylazine in the unregulated drug supply: a sequential explanatory mixed-methods study
Hill K, Minahan-Rowley R, Biegacki E, Heimer R, Sue K. Providers’ knowledge and perception of xylazine in the unregulated drug supply: a sequential explanatory mixed-methods study. Harm Reduction Journal 2024, 21: 148. PMID: 39148036, PMCID: PMC11328386, DOI: 10.1186/s12954-024-01052-4.Peer-Reviewed Original ResearchConceptsSequential explanatory mixed-methods studyExplanatory mixed-methods studyMixed-methods studyHealthcare providersHealthcare providers' experiencesHealthcare providers treating patientsSample of providersProviders treating patientsDrug supplyProvider experienceProvider knowledgeIn-depth interviewsImprove careSense of helplessnessConvenience sampleHealthcare educationThematic analysisInterview transcriptsQualitative phasePurposive samplingProvidersHealthcareOpioid supplyAbsence of literatureResultsSeventy-eightToward Realizing the Promise of AI in Precision Health Across the Spectrum of Care
Wiens J, Spector-Bagdady K, Mukherjee B. Toward Realizing the Promise of AI in Precision Health Across the Spectrum of Care. Annual Review Of Genomics And Human Genetics 2024, 25: 141-159. PMID: 38724019, DOI: 10.1146/annurev-genom-010323-010230.Peer-Reviewed Original ResearchChronic care managementSpectrum of careArtificial intelligenceClinical care decisionsAcademic medical centerEthical challengesClinical decision-makingImprove careCare decisionsPreventive careCare managementPrecision healthTertiary careLeveraging patient dataReduce inequalitiesCareMedical CenterInconsistent useSelection biasAI solutionsPatient dataMissing dataDecision-makingDesign imperfectionsIt Takes a Village: Bringing Palliative Care to Ethiopia
Reid E, Abathun E, Gebre N, Harding R, Lorenz K, Hauser J, Zerihun M, Ayers N, Connor S. It Takes a Village: Bringing Palliative Care to Ethiopia. Journal Of Palliative Medicine 2024, 27: 842-845. PMID: 38990601, DOI: 10.1089/jpm.2023.0632.Peer-Reviewed Original ResearchPalliative careCommunity-based palliative careLimited health care resourcesHighest burden of diseaseHealth care resourcesDetrimental economic effectsGlobal health researchBurden of diseaseHealth care allocationNeighborhood organizationsPoor countriesImpact of diseaseImprove careHealth careHealth researchCare resourcesPhysical sufferingCareReduce sufferingVulnerable populationsCare allocationIddirsEthiopiaEconomic effectsPoverty“Nothing Is More Powerful than Words:” How Patient Experience Narratives Enable Improvement
Grob R, Lee Y, Shaller D, Warne E, Matta S, Schlesinger M, Nembhard I. “Nothing Is More Powerful than Words:” How Patient Experience Narratives Enable Improvement. Quality Management In Health Care 2024, 33: 149-159. PMID: 38941581, DOI: 10.1097/qmh.0000000000000477.Peer-Reviewed Original ResearchConceptsPatient experience scoresExperience scoresPatient experience assessmentQuality improvement projectResponsive service provisionThematic analysis techniqueImprove careImprovement projectQualitative studyMax QDAImprovement effortsQualitative interviewsOutpatient settingOutpatient clinicCoding reportsStaff strengthImprovement workTraining needsNarrative dataDay-to-day workService provisionStaffPositive practiceInterviewsExperience assessment"Against Medical Advice" Discharges After Respiratory-Related Hospitalizations Strategies for Respectful Care
Brems J, Vick J, Ashana D, Beach M. "Against Medical Advice" Discharges After Respiratory-Related Hospitalizations Strategies for Respectful Care. CHEST Journal 2024, 166: 1155-1161. PMID: 38906461, PMCID: PMC11562651, DOI: 10.1016/j.chest.2024.05.035.Peer-Reviewed Original ResearchAgainst Medical AdviceDischarge careRespiratory-related hospitalizationsHigher-quality careLow-quality careStigmatization of patientsRespectful carePatient-centeredImprove carePrescribed inhalersDiscussion of risksEducating traineesMedical adviceCareClinicians treating patientsPopulation of patientsRespiratory conditionsCliniciansAssociated with poor outcomesCOPD exacerbationsFormal educationRespiratory diseaseHospitalCOPDPoor outcomeClassification and Surgical Management of Anorectal Malformations: A Systematic Review and Evidence-based Guideline From the APSA Outcomes and Evidence-based Practice Committee
Smith C, Rialon K, Kawaguchi A, Dellinger M, Goldin A, Acker S, Kulaylat A, Chang H, Russell K, Wakeman D, Derderian S, Englum B, Polites S, Lucas D, Ricca R, Levene T, Sulkowski J, Kelley-Quon L, Tashiro J, Christison-Lagay E, Mansfield S, Beres A, Huerta C, Ham P, Yousef Y, Rentea R, Committee T. Classification and Surgical Management of Anorectal Malformations: A Systematic Review and Evidence-based Guideline From the APSA Outcomes and Evidence-based Practice Committee. Journal Of Pediatric Surgery 2024, 59: 161598. PMID: 38997855, DOI: 10.1016/j.jpedsurg.2024.06.007.Peer-Reviewed Original ResearchSystematic reviewAnorectal malformationsEvidence-based best practicesSurgical managementConsensus-based questionsComprehensive search strategyPreferred Reporting ItemsComplex patient populationLevel of evidenceAmerican Pediatric Surgical Association OutcomesImprove careDiagnosis of anorectal malformationsGroup of anorectal malformationsTiming of surgical managementManagement of anorectal malformationsReporting ItemsLate repair groupMethod of fecal diversionTreatment of neonatesSurgical careOptimal surgical approachRate of prolapseMulti-institutional registryManagement of childrenSurgical management of anorectal malformationsHelping ourselves, helping others: the Young Women’s Breast Cancer Study (YWS) – a multisite prospective cohort study to advance the understanding of breast cancer diagnosed in women aged 40 years and younger
Rosenberg S, Zheng Y, Ruddy K, Poorvu P, Snow C, Kirkner G, Meyer M, Tamimi R, Schapira L, Peppercorn J, Come S, Borges V, Warner E, Gelber S, Collins L, Winer E, Partridge A. Helping ourselves, helping others: the Young Women’s Breast Cancer Study (YWS) – a multisite prospective cohort study to advance the understanding of breast cancer diagnosed in women aged 40 years and younger. BMJ Open 2024, 14: e081157. PMID: 38951008, PMCID: PMC11218027, DOI: 10.1136/bmjopen-2023-081157.Peer-Reviewed Original ResearchConceptsYoung Women's Breast Cancer StudyMultisite prospective cohort studyBreast Cancer StudyProspective cohort studyStage 0-IV breast cancerBreast cancerCohort studyOlder womenDied of breast cancerFear of recurrencePatient-reported outcome dataYoung womenCancer studiesClinical data abstractionPost-traumatic stressQuality of lifeImprove careFollow-upPsychosocial outcomesYoung survivorsCommunity sitesBiospecimen collectionUnderstudied populationData abstractionOutcome dataImproving Emergency Department Care for Suicidality in Autism: Perspectives from Autistic Youth, Caregivers, and Clinicians
Cervantes P, Palinkas L, Conlon G, Richards-Rachlin S, Sullivan K, Baroni A, Horwitz S. Improving Emergency Department Care for Suicidality in Autism: Perspectives from Autistic Youth, Caregivers, and Clinicians. Journal Of Autism And Developmental Disorders 2024, 1-14. PMID: 38819705, DOI: 10.1007/s10803-024-06364-9.Peer-Reviewed Original ResearchEmergency departmentSuicide risk assessment toolsEmergency department careSuicide risk screeningSuicide riskNon-autistic youthAutistic youthRisk assessment toolSemi-structured interviewsED careImprove careProviding careED settingRisk screeningFamily involvementParticipants' perspectivesCareSelf-harmAssessment toolSystem issuesAutistic patientsDevelopment of recommendationsPilot studyCaregiversSuicidal ideation
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