2024
Critical research gaps in treating growth faltering in infants under 6 months: A systematic review and meta-analysis
Tomori C, O’Connor D, Ververs M, Orta-Aleman D, Paone K, Budhathoki C, Pérez-Escamilla R. Critical research gaps in treating growth faltering in infants under 6 months: A systematic review and meta-analysis. PLOS Global Public Health 2024, 4: e0001860. PMID: 38190356, PMCID: PMC10773941, DOI: 10.1371/journal.pgph.0001860.Peer-Reviewed Original ResearchWeight gainHigh riskSystematic reviewInfant formulaChild health outcomesFull-text eligibilityGrowth falteringInclusion criteriaLactation supportModerate heterogeneityHealth outcomesInfantsSmall sample sizeStatistical differenceBangladeshi studyMonthsSupplemental milkSignificant differencesCOVID-19 pandemicInterventionHigh rateHigh attritionTrialsDF-100Eligibility
2023
Impact of Preoperative Frailty on Outcomes in Patients with Cervical Spondylotic Myelopathy Undergoing Anterior vs. Posterior Cervical Surgery
Elsamadicy A, Sayeed S, Sherman J, Craft S, Reeves B, Lo S, Shin J, Sciubba D. Impact of Preoperative Frailty on Outcomes in Patients with Cervical Spondylotic Myelopathy Undergoing Anterior vs. Posterior Cervical Surgery. Journal Of Clinical Medicine 2023, 13: 114. PMID: 38202121, PMCID: PMC10779741, DOI: 10.3390/jcm13010114.Peer-Reviewed Original ResearchNon-routine dischargeHealthcare resource utilizationAdverse eventsHealth care utilizationFrail patientsIndependent predictorsPreoperative frailtySevere frailtyExtended LOSCare utilizationFrail cohortIncidence of AEsGreater health care utilizationMultivariate logistic regression analysisMore frail patientsPosterior cervical decompressionRetrospective cohort studyAnterior cervical discectomyPerioperative adverse eventsAdditional prospective studiesNational Inpatient SamplePosterior cervical surgeryLogistic regression analysisHigh rateCervical decompressionVirtual Design of the Brain Health Support Program and CAN‐THUMBS UP
Feldman H, Belleville S, Nygaard H, Montero‐Odasso M, Chertkow H, Group C. Virtual Design of the Brain Health Support Program and CAN‐THUMBS UP. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.075153.Peer-Reviewed Original ResearchRisk of dementiaHealth support programRisk factorsMultidomain interventionEducational interventionPilot studyLifestyle intervention trialModifiable lifestyle factorsDementia risk factorsPopulation attributable riskClinical trial developmentHome-based interventionCohort of individualsHigh rateOnline educational interventionHome saliva collectionTarget enrollmentLifestyle factorsIntervention trialsAttributable riskPlatform trialsInterventional approachesTrial developmentStrong rationaleSupport programsPrior Diagnosis of Opioid-Related Disorder Is Associated With Higher Medical Resource Utilization Following Primary Hip Arthroscopy: A National Database Study
Monahan P, Surucu S, Pahapill N, Jimenez A, Taylor K. Prior Diagnosis of Opioid-Related Disorder Is Associated With Higher Medical Resource Utilization Following Primary Hip Arthroscopy: A National Database Study. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2023, 40: 2021-2028.e1. PMID: 38142868, DOI: 10.1016/j.arthro.2023.12.008.Peer-Reviewed Original ResearchOpioid-related disordersPrimary hip arthroscopyPropensity-matched groupsMedical resource utilizationAdverse eventsHip arthroscopyAntidepressant prescriptionsRevision surgeryHigher medical resource utilizationNational database studyPostoperative adverse eventsCurrent Procedural Terminology codesRevision surgery ratesYear of surgeryDay of procedureEmergency department visitsPhysical therapy evaluationMajor depressive disorderAlcohol-related disordersProcedural Terminology codesHigh rateTriNetX databaseRevision arthroscopyCohort studyDepartment visitsReimagination through renovation: incorporating couplet care in a level 4 academic NICU
Redmond B, Gambardella T, Bruno C. Reimagination through renovation: incorporating couplet care in a level 4 academic NICU. Journal Of Perinatology 2023, 43: 26-29. PMID: 38086963, DOI: 10.1038/s41372-023-01814-1.Peer-Reviewed Original ResearchAcute Adverse Events After Iodinated Contrast Agent Administration of 359,977 Injections: A Single-Center Retrospective Study
McDonald J, Larson N, Schmitz J, Kolbe A, Hunt C, Hartman R, Hagan J, Kallmes D, McDonald R. Acute Adverse Events After Iodinated Contrast Agent Administration of 359,977 Injections: A Single-Center Retrospective Study. Mayo Clinic Proceedings 2023, 98: 1820-1830. PMID: 38043998, DOI: 10.1016/j.mayocp.2023.02.032.Peer-Reviewed Original ResearchConceptsNon-white patientsWhite patientsExamination variablesSingle-center retrospective studyHigh rateAcute adverse eventsEffect of patientAllergic-like reactionsPhysiologic reactionsComputed tomography examinationCT locationLogistic regression modelsContrast agent administrationICM allergyYounger patientsAdverse eventsPatient ageMultivariable analysisRetrospective studyUnique patientsAcute reactionsFemale sexPatient variablesTomography examinationCT examinationsRight Heart Failure in the Intensive Care Unit: Etiology, Pathogenesis, Diagnosis, and Treatment
Tarras E, Khosla A, Heerdt P, Singh I. Right Heart Failure in the Intensive Care Unit: Etiology, Pathogenesis, Diagnosis, and Treatment. Journal Of Intensive Care Medicine 2023, 40: 119-136. PMID: 38031338, DOI: 10.1177/08850666231216889.Peer-Reviewed Original ResearchRight heart failureFailure patientsHeart failureTreatment optionsIntensive care unit settingMechanical circulatory support devicesIntensive care unitCirculatory support devicesCardio-pulmonary physiologyCare unitDifferent pharmacotherapiesUnit settingClinical guidancePathophysiological manifestationsCirculatory physiologyIntensivistsPatientsSupport devicesSupport optionsCirculatory systemHigh rateTreatmentDiagnosisFailureOptionsComprehensive genomic characterization of HER2-low and HER2-0 breast cancer
Tarantino P, Gupta H, Hughes M, Files J, Strauss S, Kirkner G, Feeney A, Li Y, Garrido-Castro A, Barroso-Sousa R, Bychkovsky B, DiLascio S, Sholl L, MacConaill L, Lindeman N, Johnson B, Meyerson M, Jeselsohn R, Qiu X, Li R, Long H, Winer E, Dillon D, Curigliano G, Cherniack A, Tolaney S, Lin N. Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer. Nature Communications 2023, 14: 7496. PMID: 37980405, PMCID: PMC10657399, DOI: 10.1038/s41467-023-43324-w.Peer-Reviewed Original ResearchConceptsHER2-low tumorsBreast cancerHER2-negative metastatic breast cancerMetastatic breast cancerTumor mutational burdenHigh rateComprehensive genomic characterizationHER2 0Mutational burdenBreast tumorsTumorsHER2Genomic alterationsNext-generation sequencingSignificant differencesGenomic findingsCancerGenomic landscapeMolecular underpinningsHemideletionGenomic characterizationHigher numberPatientsCopy countsPerspectives of Adolescents and Young Adults with Sickle Cell Disease and Clinicians on Improving Transition Readiness and a Videogame Intervention
Aronson P, Nolan S, Schaeffer P, Hieftje K, Ponce K, Calhoun C. Perspectives of Adolescents and Young Adults with Sickle Cell Disease and Clinicians on Improving Transition Readiness and a Videogame Intervention. Blood 2023, 142: 5116. DOI: 10.1182/blood-2023-173310.Peer-Reviewed Original ResearchAdult careSickle cell diseaseTransition readinessPatient engagementClinician experienceVideogame interventionCell diseaseMedical decisionsYoung adultsDisease-specific knowledgeQuaternary care hospitalYoung SCD patientsSuccessful home managementHigh rateParents/caregiversPain crisisCare hospitalPatient factorsSuccessful disease managementHealthcare utilizationSCD patientsClinical manifestationsEmergency departmentProvider judgmentClinician's perspectiveIntensive Induction Chemotherapy (IC) Vs Hypomethylating Agents + Venetoclax (HMA/VEN) in IDH1- or IDH2-Mutant Newly Diagnosed Acute Myeloid Leukemia (AML) - a Multicenter Cohort Study
Bewersdorf J, Shimony S, Shallis R, Liu Y, Schaefer E, Zeidan A, Goldberg A, Stein E, Marcucci G, Lindsley R, Chen E, Ramos J, Stein A, DeAngelo D, Neuberg D, Stone R, Ball B, Stahl M. Intensive Induction Chemotherapy (IC) Vs Hypomethylating Agents + Venetoclax (HMA/VEN) in IDH1- or IDH2-Mutant Newly Diagnosed Acute Myeloid Leukemia (AML) - a Multicenter Cohort Study. Blood 2023, 142: 1589. DOI: 10.1182/blood-2023-174283.Peer-Reviewed Original ResearchIntensive induction chemotherapyAcute myeloid leukemiaComposite complete responseMedian overall survivalOverall survivalComplete responseIDH2 mutationsAllo-SCTLarge multicenter retrospective cohort studyMulticenter retrospective cohort studyAllogeneic stem cell transplantationSecondary acute myeloid leukemiaComparable overall survivalIDH1 inhibitor ivosidenibHigh rateRetrospective cohort studyStem cell transplantationLog-rank testStandard of careLarge academic centerYears of ageEffect of treatmentIDH-mutant AMLMultivariable stepwiseFit patientsAligning public health and public safety: Probation as a touchpoint to identify and link patients with opioid use disorder to opioid agonist treatment
Bromberg D, Galvez de Leon S, Litz T, Azbel L, Liberman A, Polonsky M, Dvoriak S, Saichuk N, Taxman F, Altice F. Aligning public health and public safety: Probation as a touchpoint to identify and link patients with opioid use disorder to opioid agonist treatment. PLOS Global Public Health 2023, 3: e0002349. PMID: 37910486, PMCID: PMC10619786, DOI: 10.1371/journal.pgph.0002349.Peer-Reviewed Original ResearchCriminal justice settingsOpioid use disorderBrief interventionUse disordersPrevalence of OUDProbation centersHIV prevention effortsJustice settingsMental healthHigh rateCommunity supervision settingsOAT servicesSBIRT interventionAgonist therapyHIV testingOpioid dependenceAgonist treatmentConsecutive individualsTreatment strategiesGeneral populationProbationSBIRTPrevention effortsSupervision settingParticipantsResponsive Neurostimulation for People With Drug-Resistant Epilepsy and Autism Spectrum Disorder
Fields M, Marsh C, Eka O, Johnson E, Marcuse L, Kwon C, Young J, LaVega-Talbott M, Kurukumbi M, Von Allmen G, Zempel J, Friedman D, Jette N, Singh A, Yoo J, Blank L, Panov F, Ghatan S. Responsive Neurostimulation for People With Drug-Resistant Epilepsy and Autism Spectrum Disorder. Journal Of Clinical Neurophysiology 2023, 41: 64-71. PMID: 35512185, PMCID: PMC10756699, DOI: 10.1097/wnp.0000000000000939.Peer-Reviewed Original ResearchConceptsDrug-resistant epilepsySuper respondersSeizure reductionPromising surgical optionResponsive neurostimulator systemRNS SystemAutism spectrum disorderSurgical candidatesSurgical evaluationSurgical optionsMulticenter studySpectrum disorderGeneral populationResponsive neurostimulationPatientsResponse rateSmall cohortEpilepsyNeurostimulator systemHigh rateRespondersDescriptive statisticsSystem placementBehavioral outcomesDisordersThe known unknowns of Powassan virus ecology
Brackney D, Vogels C. The known unknowns of Powassan virus ecology. Journal Of Medical Entomology 2023, 60: 1142-1148. PMID: 37862099, PMCID: PMC10645372, DOI: 10.1093/jme/tjad095.Peer-Reviewed Original ResearchPlacebo’s role in the rapid antidepressant effect
Sanacora G, Colloca L. Placebo’s role in the rapid antidepressant effect. Nature Mental Health 2023, 1: 820-821. DOI: 10.1038/s44220-023-00141-w.Peer-Reviewed Original ResearchRandomized placebo-controlled studyPlacebo-controlled studyRapid antidepressant effectsRapid antidepressant responseRapid antidepressant actionsStudy arm assignmentAntidepressant actionAntidepressant effectsAntidepressant responseSurgical anesthesiaTreatment assignmentHigh ratePlaceboAnesthesiaKetaminePredictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative
Burdick K, Millett C, Yocum A, Altimus C, Andreassen O, Aubin V, Belzeaux R, Berk M, Biernacka J, Blumberg H, Cleare A, Diaz-Byrd C, Dubertret C, Etain B, Eyler L, Forester B, Fullerton J, Frye M, Gard S, Godin O, Haffen E, Klaus F, Lagerberg T, Leboyer M, Martinez-Aran A, McElroy S, Mitchell P, Olie E, Olorunfemi P, Passerieux C, Peters A, Pham D, Polosan M, Potter J, Sajatovic M, Samalin L, Schwan R, Shanahan M, Solé B, Strawbridge R, Stuart A, Torres I, Ueland T, Vieta E, Williams L, Wrobel A, Yatham L, Young A, Nierenberg A, McInnis M. Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative. FOCUS The Journal Of Lifelong Learning In Psychiatry 2023, 21: 444-452. PMID: 38694997, PMCID: PMC11058953, DOI: 10.1176/appi.focus.23021021.Peer-Reviewed Original ResearchBipolar disorderFunctional impairmentComplete recoveryComorbid substance use disorderPersistent functional impairmentPatient's complete recoveryLogistic regression analysisPrior mood episodesProspective longitudinal studySubstance use disordersPsychotropic medicationsHeterogeneous presentationMood episodesClinical research communityDepressive symptomsOptimizing outcomesUse disordersCohortLower functioningLongitudinal studyRegression analysisGreater total numberHigh rateMultiple cohortsImpairmentIntravenous thrombolysis prior to endovascular thrombectomy in elderly stroke patients: An analysis of the National Inpatient Sample database
Chen H, Khunte M, Colasurdo M, Malhotra A, Gandhi D. Intravenous thrombolysis prior to endovascular thrombectomy in elderly stroke patients: An analysis of the National Inpatient Sample database. Journal Of The Neurological Sciences 2023, 454: 120842. PMID: 37856997, DOI: 10.1016/j.jns.2023.120842.Peer-Reviewed Original ResearchConceptsNational Inpatient Sample databaseHospital mortalityHemorrhagic complicationsIntravenous thrombolysisEndovascular thrombectomyEVT patientsIVT treatmentThrombectomy centreElderly patientsMultivariable logistic regression modelSample databaseStroke risk factorsElderly stroke patientsCross-sectional studyLarge-scale cross-sectional studyOutcomes of interestHigh rateLogistic regression modelsPatients 80Medical comorbiditiesOnly patientsPatient demographicsStroke etiologyThrombolytic treatmentHemorrhagic riskIntracardiac vs Transesophageal Echocardiography for Left Atrial Appendage Occlusion With Watchman FLX in the U.S.
Ferro E, Alkhouli M, Nair D, Kapadia S, Hsu J, Gibson D, Freeman J, Price M, Roy K, Allocco D, Yeh R, Piccini J. Intracardiac vs Transesophageal Echocardiography for Left Atrial Appendage Occlusion With Watchman FLX in the U.S. JACC Clinical Electrophysiology 2023, 9: 2587-2599. PMID: 37831030, DOI: 10.1016/j.jacep.2023.08.004.Peer-Reviewed Original ResearchConceptsAtrial appendage occlusionTransesophageal echocardiographyIntracardiac echocardiographyBaseline characteristicsAppendage occlusionLeft atrial appendage occlusionPericardial effusion rateSuccessful device implantationAdverse event ratesSimilar baseline characteristicsUnadjusted mortality ratesHigh rateICE patientsTEE patientsPericardial effusionPivotal trialsDevice implantationGeneral anesthesiaAdjusted comparisonsProcedural timeLAAO devicesDevice deliveryMortality rateEvent ratesEchocardiographyAlmajiri health; a scoping review on disease, health literacy and space for participatory research
Muhammad M, Abdulsalam A, Petit-Clair F, Acquaye A, Nobles A, Fleischer B, Konkwo C, Ransome Y, Paintsil E. Almajiri health; a scoping review on disease, health literacy and space for participatory research. PLOS Global Public Health 2023, 3: e0001641. PMID: 37819921, PMCID: PMC10566680, DOI: 10.1371/journal.pgph.0001641.Peer-Reviewed Original ResearchPoor oral hygieneUrinary tract infectionCase-control studyCross-sectional studyHigh rateOral healthTract infectionsIntestinal parasitosisOral hygieneUrinary schistosomiasisHealth literacyPsychiatric disordersRabies awarenessHealth determinantsHealth outcomesHealth problemsHealth statusMale childrenOccupational injuriesSocio-ecological modelDemographic featuresInfectious diseasesStudy designMental healthN. meningitidisS1009 Higher Rates of Delay in Starting Advanced Inflammatory Bowel Disease Therapy for Biologics Given Via Infusion Centers
Xiao K, Gottesman S, Nguyen H, Hernandez E, Anand T, Saweris E, Jaganathan P, Jafri F, Davis J, Tong K, Gaidos J, Feagins L. S1009 Higher Rates of Delay in Starting Advanced Inflammatory Bowel Disease Therapy for Biologics Given Via Infusion Centers. The American Journal Of Gastroenterology 2023, 118: s764-s765. DOI: 10.14309/01.ajg.0000953676.10735.44.Peer-Reviewed Original ResearchExperiences of stigma, mental health, and coping strategies in Lebanon among Lebanese and displaced Syrian men who have sex with men: A qualitative study
Abboud S, Seal D, Pachankis J, Khoshnood K, Khouri D, Fouad F, Heimer R. Experiences of stigma, mental health, and coping strategies in Lebanon among Lebanese and displaced Syrian men who have sex with men: A qualitative study. Social Science & Medicine 2023, 335: 116248. PMID: 37742387, DOI: 10.1016/j.socscimed.2023.116248.Peer-Reviewed Original ResearchMental healthAvailable mental health servicesMental health servicesSexual health risksMental health resourcesMental health risksHealth risksAdverse childhood experiencesSocial support interventionsQualitative studyExperiences of stigmaHealth servicesRecent exposureSupport interventionsLarger studyHealth resourcesMSMCommon stigmaSocial isolationMenHigh rateSexSyrian menChildhood experiencesHealth
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply