2025
Exposome-Wide Gene-By-Environment Interaction Study of Psychotic Experiences in the UK Biobank
Lin B, Pries L, Arias-Magnasco A, Klingenberg B, Linden D, Blokland G, van der Meer D, Luykx J, Rutten B, Guloksuz S. Exposome-Wide Gene-By-Environment Interaction Study of Psychotic Experiences in the UK Biobank. Biological Psychiatry Global Open Science 2025, 5: 100460. DOI: 10.1016/j.bpsgos.2025.100460.Peer-Reviewed Original ResearchGene-by-environment interactionsPRS-SCZUK BiobankExposome-wide association studyPsychotic experiencesPolygenic risk scoresAssociated with psychotic experiencesMental distressRisk scoreAssociation studiesSleep problemsBiobankAdditive interactionPsychosis riskAgnostic analysisCorrelation testXWASGenetic vulnerabilityDistressParticipantsScoresCorrelation analysisExposureStudyRisk
2024
Delineating Urbanicity and Rurality: Impact on Environmental Exposure Assessment
Song Y, Deziel N, Bell M. Delineating Urbanicity and Rurality: Impact on Environmental Exposure Assessment. Environmental Science And Technology 2024, 58: 19178-19188. PMID: 39412270, PMCID: PMC11627196, DOI: 10.1021/acs.est.4c06942.Peer-Reviewed Original ResearchConceptsEnvironmental exposuresEnvironmental exposure assessmentExposure of particulate matterUrban/rural disparitiesDemographic compositionHealth StudyHealth researchPopulation-basedClassification systemExposure assessmentSpatial patternsHealth impactsRural areasHealthRuralParticulate matterLand surface temperatureWest VirginiaUnited StatesSurface temperatureUrbanizationResearch questionsAssessmentDisparitiesExposureCannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function
Metz T, Allshouse A, McMillin G, Greene T, Chung J, Grobman W, Haas D, Mercer B, Parry S, Reddy U, Saade G, Simhan H, Silver R. Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function. Obstetric Anesthesia Digest 2024, 44: 139-140. DOI: 10.1097/01.aoa.0001026572.72882.bd.Peer-Reviewed Original ResearchExposure to cannabisCannabis usePlacental functionPregnancy outcomesPrevalence of cannabis usePoor fetal growthAdverse pregnancy outcomesInfluence pregnancy outcomePlacental dysfunctionCannabis exposureFetal growthPregnant individualsSelf-reported useTobacco useCannabisDrug usePregnancyOutcome relationsPotential legal consequencesOutcomesAssociationExposureUseDysfunctionPublished researchCannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function
Metz T, Allshouse A, McMillin G, Greene T, Chung J, Grobman W, Haas D, Mercer B, Parry S, Reddy U, Saade G, Simhan H, Silver R. Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function. Obstetrical & Gynecological Survey 2024, 79: 307-309. DOI: 10.1097/ogx.0000000000001289.Peer-Reviewed Original ResearchWildfires increasingly threaten oil and gas wells in the western United States with disproportionate impacts on marginalized populations
González D, Morello-Frosch R, Liu Z, Willis M, Feng Y, McKenzie L, Steiger B, Wang J, Deziel N, Casey J. Wildfires increasingly threaten oil and gas wells in the western United States with disproportionate impacts on marginalized populations. One Earth 2024, 7: 1044-1055. PMID: 39036466, PMCID: PMC11259100, DOI: 10.1016/j.oneear.2024.05.013.Peer-Reviewed Original ResearchWildfire burned areaWestern United StatesBurned areaThreat of wildfireHigh wildfire riskExposure of human populationsWildfire riskWildfireHuman healthClimate changeNational oilHuman populationHistorical threatDisproportionate impactUnited StatesAreaExposureGas wellsClimateOilPopulationWellsGas productionGasHeat exposure induced risks of preterm birth mediated by maternal hypertension
Wang L, Di J, Wang Q, Zhang H, Zhao W, Shi X, Di Q, Ji J, Liang W, Huang C. Heat exposure induced risks of preterm birth mediated by maternal hypertension. Nature Medicine 2024, 30: 1974-1981. PMID: 38750350, DOI: 10.1038/s41591-024-03002-w.Peer-Reviewed Original ResearchRisk of maternal hypertensionRisk of preterm birthMaternal hypertensionPreterm birthClinical subtypes of preterm birthIncreased risk of preterm birthSubtypes of preterm birthIncidence of preterm birthBlood pressureMaternal blood pressureSingleton live birthsElevated blood pressureGestational weeksLarge-population studiesEarly pregnancyLive birthsClinical subtypesCohort studyIncreased riskHypertensionBirthMediation analysisEffects of heat exposureHeat exposureExposureSources of exposure to non-tobacco nicotine electronic nicotine delivery systems and associations with susceptibility to use and use behaviors among young adults in the United States
Li W, Kong G, Davis D, Bold K, Krishnan-Sarin S, Camenga D, Morean M. Sources of exposure to non-tobacco nicotine electronic nicotine delivery systems and associations with susceptibility to use and use behaviors among young adults in the United States. PLOS ONE 2024, 19: e0299533. PMID: 38718067, PMCID: PMC11078344, DOI: 10.1371/journal.pone.0299533.Peer-Reviewed Original ResearchConceptsElectronic nicotine delivery systemsAssociated with greater oddsNicotine delivery systemsGreater oddsYoung adultsTobacco product useTobacco-free nicotineDelivery systemLifetime useENDS usePast-monthExamined associationsNicotineSocial mediaPrevention effortsOddsAdultsSusceptibilityAnalyzed online survey dataStreaming platformsExposureUrinary biomonitoring of glyphosate exposure among male farmers and nonfarmers in the Biomarkers of Exposure and Effect in Agriculture (BEEA) study
Chang V, Ospina M, Xie S, Andreotti G, Parks C, Liu D, Madrigal J, Ward M, Rothman N, Silverman D, Sandler D, Friesen M, Beane Freeman L, Calafat A, Hofmann J. Urinary biomonitoring of glyphosate exposure among male farmers and nonfarmers in the Biomarkers of Exposure and Effect in Agriculture (BEEA) study. Environment International 2024, 187: 108644. PMID: 38636272, DOI: 10.1016/j.envint.2024.108644.Peer-Reviewed Original ResearchConceptsUrinary glyphosate concentrationsBiomarkers of exposure and effectGlyphosate concentrationsExposure and effectGlyphosate usePesticide exposureGeometric mean concentrationsBiomonitoring dataMean concentrationsUrinary biomonitoringGlyphosate exposureAgricultural settingsGlyphosateSelf-reported pesticide exposureExposed farmersExposure determinantsIsotope-dilution tandem mass spectrometryConcentrationMorning voided urineAgricultureTandem mass spectrometryBiomonitoringExposureFarmsVoided urineCausal Selection of Covariates in Regression Calibration for Mismeasured Continuous Exposure
Tang W, Spiegelman D, Liao X, Wang M. Causal Selection of Covariates in Regression Calibration for Mismeasured Continuous Exposure. Epidemiology 2024, 35: 320-328. PMID: 38630507, DOI: 10.1097/ede.0000000000001706.Peer-Reviewed Original ResearchConceptsMismeasured exposureOutcome modelRegression calibrationMeasurement error modelSelection of covariatesNonparametric settingEffect modificationCovariate adjustmentFiber intakeMeasurement errorCardiovascular diseaseEffects of fiber intakeStudy datasetOutcomesCovariatesComprehensive guidanceError modelRegressionHealthEfficiency lossErrorRosnerWillettExposureAdjustmentA unified framework for assessing interaction effects among environmental exposures in epidemiologic studies: A case study on temperature, air pollution, and kidney-related conditions in New York state
Chu L, Chen K, Yang Z, Crowley S, Dubrow R. A unified framework for assessing interaction effects among environmental exposures in epidemiologic studies: A case study on temperature, air pollution, and kidney-related conditions in New York state. Environmental Research 2024, 248: 118324. PMID: 38301759, DOI: 10.1016/j.envres.2024.118324.Peer-Reviewed Original ResearchAir pollutionMultiplicative interaction effectsNew York StateEstimated health burdenCase-crossover designEvaluation of effect modificationBi-variate associationsAssess interaction effectsConditional logistic modelMeasures of exposureInteraction effectsEffect modificationPollutionExposure variablesHealth burdenEpidemiological studiesEnvironmental exposuresLog-linear modelLogistic modelInteraction termsQuantitative frameworkAirCase studyExposureAlert systemEffects of child trauma screening on trauma‐informed multidisciplinary evaluation and service planning in the child welfare system
Connell C, Swanson A, Genovese M, Lang J. Effects of child trauma screening on trauma‐informed multidisciplinary evaluation and service planning in the child welfare system. Journal Of Traumatic Stress 2024, 37: 337-343. PMID: 38193592, DOI: 10.1002/jts.23001.Peer-Reviewed Original ResearchRecord reviewMultidisciplinary evaluationTrauma screeningLong-term sequelaeRetrospective record reviewPrevalence of exposureEvidence-based interventionsTrauma-focused servicesTrauma-related symptomsProvider recommendationEarly identificationPTE exposureService planningChild welfare systemRandom sampleScreening procedureFormal screening procedureTraumatic eventsChild maltreatmentSignificant improvementChildrenExposureScreeningScreening processLt1,4-Dioxane
Stouffer A, Erickson C, Krick M, Chen Y, Ginsberg G, Loch-Caruso R, Jones R, Madrigal J, Thompson D, Vasliou V. 1,4-Dioxane. 2024, 843-849. DOI: 10.1016/b978-0-12-824315-2.00831-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPersistent environmental contaminationEnvironmental contaminationEnvironmental behaviorEnvironmental releaseChemical intermediatesWater solubilityPotential negative health effectsDioxaneRecent decadesSoilConsumer productsGroundwaterContaminationHealth effectsSolventSolubilityIntermediatesNegative health effectsStabilizerManagementUsesProductsUseToxicityExposureAcute Effects of Exposure to Fine Particulate Matter and Its Constituents on Sex Hormone Among Postmenopausal Women — Beijing, Tianjin, and Hebei PLADs, China, 2018–2019
Tian Y, Wang J, Fang J, Chen C, Zhao F, Zhang Y, Du P, Li Y, Shi W, Liu Y, Ding E, Tang S, Yue X, Shi X. Acute Effects of Exposure to Fine Particulate Matter and Its Constituents on Sex Hormone Among Postmenopausal Women — Beijing, Tianjin, and Hebei PLADs, China, 2018–2019. China CDC Weekly 2024, 6: 249-253. PMID: 38633202, PMCID: PMC11018549, DOI: 10.46234/ccdcw2024.049.Peer-Reviewed Original ResearchExposure to fine particulate matterFine particulate matterParticulate matterComponents of PM<sub>2.5</sub>Exposure to PM<sub>2.5</sub>Effects of exposure to fine particulate matterWater-soluble ionsBalance of sex hormonesPrevalence of air pollutionAir pollutionHormone disruptionInorganic elementsParticle componentsMatterHgCdPollutionBeijingNiReproductive systemExposureSbSeHebeiTianjinAmygdala response to emotional faces following acute administration of psilocybin in healthy individuals
Armand S, Larsen K, Madsen M, Ozenne B, Preller K, Knudsen G, Stenbæk D, Fisher P. Amygdala response to emotional faces following acute administration of psilocybin in healthy individuals. Neuroscience Applied 2024, 3: 103934. DOI: 10.1016/j.nsa.2023.103934.Peer-Reviewed Original ResearchPlasma psilocin levelsFunctional magnetic resonance imagingAmygdala reactivityHealthy individualsAmygdala responseMagnetic resonance imagingAcute administrationDrug intensityAcute exposureTherapeutic outcomesResonance imagingSignificant associationBrain regionsPsychedelic psilocybinPsilocybinBaselineFuture studiesSignificant changesExposureFearful facesEmotion processingResponseIndividualsAdministration
2023
Eviction as a community health exposure
Schwartz G, Leifheit K, Arcaya M, Keene D. Eviction as a community health exposure. Social Science & Medicine 2023, 340: 116496. PMID: 38091853, PMCID: PMC11249083, DOI: 10.1016/j.socscimed.2023.116496.Peer-Reviewed Original ResearchAssociations of Trimester-Specific Exposure to Perchlorate, Thiocyanate, and Nitrate with Childhood Neurodevelopment: A Birth Cohort Study in China
Li J, Tu F, Wan Y, Qian X, Mahai G, Wang A, Ma J, Yang Z, Xia W, Xu S, Zheng T, Li Y. Associations of Trimester-Specific Exposure to Perchlorate, Thiocyanate, and Nitrate with Childhood Neurodevelopment: A Birth Cohort Study in China. Environmental Science And Technology 2023, 57: 20480-20493. PMID: 38015815, DOI: 10.1021/acs.est.3c06013.Peer-Reviewed Original ResearchMental Development IndexOffspring neurodevelopmentMaternal exposureQuantile sum regression analysesTrimester-specific analysesTrimester-specific exposureBirth cohort studyRegression analysisBayesian kernel machine regression (BKMR) analysisCohort studyEarly pregnancyFirst trimesterSecond trimesterPrenatal exposureChildhood neurodevelopmentUrinary thiocyanateBirth cohortTrimesterNeurodevelopmentUrine samplesSensitive windowExposureAssociationMixture exposurePoint decreaseAssociations between weekly gestational exposure of fine particulate matter, ozone, and nitrogen dioxide and preterm birth in a North Carolina Birth Cohort, 2003–2015
Krajewski A, Luben T, Warren J, Rappazzo K. Associations between weekly gestational exposure of fine particulate matter, ozone, and nitrogen dioxide and preterm birth in a North Carolina Birth Cohort, 2003–2015. Environmental Epidemiology 2023, 7: e278. PMID: 38912391, PMCID: PMC11189686, DOI: 10.1097/ee9.0000000000000278.Peer-Reviewed Original ResearchPreterm birthGestational exposureWeeks of pregnancyRisk of PTBInterquartile range increasePM 2.5 exposurePoisson regression modelsGestational weeksPotential confoundersFine particulate matterAssociation magnitudeRisk differenceNull associationBirth cohortExposure windowsResidential addressesMultipollutant modelsBirthWeeksPositive associationAssociationExposurePM 2.5Regression modelsCensus tractsChronic respiratory symptoms following deployment-related occupational and environmental exposures among US veterans
Garshick E, Redlich C, Korpak A, Timmons A, Smith N, Nakayama K, Baird C, Ciminera P, Kheradmand F, Fan V, Hart J, Koutrakis P, Kuschner W, Ioachimescu O, Jerrett M, Montgrain P, Proctor S, Wan E, Wendt C, Wongtrakool C, Blanc P. Chronic respiratory symptoms following deployment-related occupational and environmental exposures among US veterans. Occupational And Environmental Medicine 2023, 81: 59-65. PMID: 37968126, PMCID: PMC10872566, DOI: 10.1136/oemed-2023-109146.Peer-Reviewed Original ResearchChronic respiratory symptomsRespiratory symptomsUS veteransPit smokeChronic bronchitisInhalational exposureInterviewer-administered questionnaireCross-sectional studySmoke exposureHeavy exposureVGDFDeployment exposuresSymptomsExposure itemsItem reductionEnvironmental exposuresScore incrementsWheezeBronchitisExposure frequencyVeteransExposureLogit linkMonthsSmokeAtmospheric elemental carbon pollution and its regional health disparities in China
Hang Y, Meng X, Xi Y, Zhang D, Lin X, Liang F, Tian H, Li T, Wang T, Cao J, Fu Q, Dey S, Li S, Huang K, Kan H, Shi X, Liu Y. Atmospheric elemental carbon pollution and its regional health disparities in China. Environmental Research Letters 2023, 18: 124017. PMID: 39036363, PMCID: PMC11259311, DOI: 10.1088/1748-9326/ad0862.Peer-Reviewed Original ResearchAssessment of a Novel Interactive Website to Inform Adolescent and Young Adult Decision-Making about Contraception
Lepore C, McNamara M, Miclette K, Vash-Margita A. Assessment of a Novel Interactive Website to Inform Adolescent and Young Adult Decision-Making about Contraception. Journal Of Pediatric And Adolescent Gynecology 2023, 37: 149-155. PMID: 37935279, DOI: 10.1016/j.jpag.2023.10.006.Peer-Reviewed Original ResearchOral contraceptive pillsYoung adultsNon-contraceptive usesTertiary children's hospitalReproductive health informationTeen healthWebsite exposureChildren's HospitalMean ageOutpatient clinicContraceptive pillsContraception methodsHealth educationExposure surveyParticipant demographicsAYAsConvenience sampleHealth informationAdolescent HealthElectronic surveyFurther studiesClinical institutionsHospitalContraceptionExposure
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