2015
A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder
Talati A, Pantazatos SP, Hirsch J, Schneier F. A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder. Psychiatry Research 2015, 231: 279-285. PMID: 25659476, PMCID: PMC4363180, DOI: 10.1016/j.pscychresns.2015.01.008.Peer-Reviewed Original ResearchConceptsParoxetine treatmentSignificant gray matter reductionsGray matter volume changesAnxiety disordersNeuro-anatomical changesGray matter reductionsSocial anxiety disorderClinical responseLiebowitz Social Anxiety ScaleSymptom improvementRight thalamusVBM8 toolboxLeft thalamusSuccessful treatmentWeek 8Bilateral caudateControl groupGray matterDSM-IVSymptom severityLongitudinal changesPilot study
2013
Reduced Anterior Temporal and Hippocampal Functional Connectivity During Face Processing Discriminates Individuals with Social Anxiety Disorder from Healthy Controls and Panic Disorder, and Increases Following Treatment
Pantazatos SP, Talati A, Schneier FR, Hirsch J. Reduced Anterior Temporal and Hippocampal Functional Connectivity During Face Processing Discriminates Individuals with Social Anxiety Disorder from Healthy Controls and Panic Disorder, and Increases Following Treatment. Neuropsychopharmacology 2013, 39: 425-434. PMID: 24084831, PMCID: PMC3870777, DOI: 10.1038/npp.2013.211.Peer-Reviewed Original ResearchConceptsSocial anxiety disorderFunctional connectivityAnxiety disordersFace perceptionTemporal poleFunctional magnetic resonance imaging studyPanic disorderSpecific anxiety disordersIndependent replication sampleHippocampal functional connectivityMagnetic resonance imaging studyFace processingPerceptual tasksResonance imaging studyBrain activationSAD diagnosisReplication sampleHIGH-SADSAD samplesSimilar tasksDisorder-specific biomarkersFC featuresSymptom severityAnterior temporalPerception
2010
Analysis of clamping versus cutting of T3 sympathetic nerve for severe palmar hyperhidrosis
Yanagihara TK, Ibrahimiye A, Harris C, Hirsch J, Gorenstein LA. Analysis of clamping versus cutting of T3 sympathetic nerve for severe palmar hyperhidrosis. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: 984-989. PMID: 20951250, PMCID: PMC2964926, DOI: 10.1016/j.jtcvs.2010.08.014.Peer-Reviewed Original ResearchConceptsEndoscopic thoracic sympathectomyPalmar hyperhidrosisSympathetic chainQuality of lifeThoracic sympathectomySevere palmar hyperhidrosisT3 sympathectomySympathetic nervesChief complaintPatient satisfactionExcessive sweatingPatientsSympathectomyT3 levelsHyperhidrosisSymptomsHigh rateSeverityClamping techniqueClampingNerveSurgerySweatingThighComplaints
2007
Brain Activity Associated With Stimulation Therapy of the Visual Borderzone in Hemianopic Stroke Patients
Marshall RS, Ferrera JJ, Barnes A, Xian Zhang, O'Brien KA, Chmayssani M, Hirsch J, Lazar RM. Brain Activity Associated With Stimulation Therapy of the Visual Borderzone in Hemianopic Stroke Patients. Neurorehabilitation And Neural Repair 2007, 22: 136-144. PMID: 17698955, DOI: 10.1177/1545968307305522.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalAdultAgedAttentionBrainBrain MappingCerebrovascular CirculationFemaleFunctional LateralityHemianopsiaHumansMagnetic Resonance ImagingMaleMiddle AgedNeuronal PlasticityPhotic StimulationPhysical Therapy ModalitiesStrokeTreatment OutcomeVisual PathwaysVisual PerceptionConceptsVisual restoration therapyRestoration therapyHemianopic patientsAnterior cingulateHemianopic stroke patientsHigher-order visual areasBilateral anterior cingulateBilateral basal gangliaHome-based treatment programDorsolateral frontal cortexBlood oxygen level-dependent activityBrain activityFunctional magnetic resonance imagingMagnetic resonance imagingBrain Activity AssociatedCondition interactionLevel-dependent activityStroke patientsBasal gangliaBrain injuryStimulation therapyFrontal cortexMiddle temporal regionsRepetitive stimulationVisual therapy
2006
Facial Emotion Recognition after Curative Nondominant Temporal Lobectomy in Patients with Mesial Temporal Sclerosis
McClelland S, Garcia RE, Peraza DM, Shih TT, Hirsch LJ, Hirsch J, Goodman RR. Facial Emotion Recognition after Curative Nondominant Temporal Lobectomy in Patients with Mesial Temporal Sclerosis. Epilepsia 2006, 47: 1337-1342. PMID: 16922878, DOI: 10.1111/j.1528-1167.2006.00557.x.Peer-Reviewed Original ResearchConceptsMesial temporal sclerosisAnteromedial temporal lobectomyTemporal lobe epilepsyTLE onsetTemporal sclerosisTemporal lobectomyRight amygdalaEarly-onset patientsLate-onset patientsEarly-onset groupLate-onset groupAmygdalar damageAge 6 yearsFER impairmentPostsurgical populationLobe epilepsyLeft-hemisphere language dominancePreoperative MRIPatientsFrightened expressionImpaired facial emotion recognitionLobectomySclerosisAmygdalaOnset