2013
Sleep restriction increases the neuronal response to unhealthy food in normal-weight individuals
St-Onge M, Wolfe S, Sy M, Shechter A, Hirsch J. Sleep restriction increases the neuronal response to unhealthy food in normal-weight individuals. International Journal Of Obesity 2013, 38: 411-416. PMID: 23779051, PMCID: PMC3883872, DOI: 10.1038/ijo.2013.114.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingFood stimuliRight insulaUnhealthy foodsUnhealthy food stimuliNormal-weight individualsMiddle temporal gyrusLevel-dependent activityInferior parietal lobuleSuperior frontal gyrusInsula activityFrontal gyrusGreater activationNeural mechanismsTemporal gyrusParietal lobuleFood intakeOrbitofrontal cortexRestricted sleepSame stimuliNeuronal responsesSleep restrictionNeural systemsBrain rewardShort sleep duration
2012
Relation between changes in neural responsivity and reductions in desire to eat high-calorie foods following gastric bypass surgery
Ochner C, Stice E, Hutchins E, Afifi L, Geliebter A, Hirsch J, Teixeira J. Relation between changes in neural responsivity and reductions in desire to eat high-calorie foods following gastric bypass surgery. Neuroscience 2012, 209: 128-135. PMID: 22406414, PMCID: PMC3601838, DOI: 10.1016/j.neuroscience.2012.02.030.Peer-Reviewed Original ResearchConceptsLow-calorie food cuesGastric bypass surgeryPostoperative reductionPostoperative changesHigh-calorie foodsBypass surgeryNeural responsivityFood cuesSignificant postoperative reductionReward-related neural activationFunctional magnetic resonance imagingMagnetic resonance imagingDopaminergic reward pathwayLow-calorie foodsObesity surgeryLiking of foodNeural changesReward pathwayResonance imagingOne monthSurgeryRating ScaleInhibitory activationNeural activationRYGBSleep restriction leads to increased activation of brain regions sensitive to food stimuli
St-Onge MP, McReynolds A, Trivedi ZB, Roberts AL, Sy M, Hirsch J. Sleep restriction leads to increased activation of brain regions sensitive to food stimuli. American Journal Of Clinical Nutrition 2012, 95: 818-824. PMID: 22357722, PMCID: PMC3302360, DOI: 10.3945/ajcn.111.027383.Peer-Reviewed Original ResearchConceptsFood stimuliNeuronal activityHabitual sleepSleep restrictionNormal-weight menOverall neuronal activityAverage sleep durationFunctional magnetic resonance imagingMagnetic resonance imagingPartial sleep restrictionCrossover studyEpidemiologic evidenceClinical studiesNeuronal activationNucleus accumbensSleep durationFasted stateResonance imagingBrain regionsDay 6Prefrontal cortexSleepBrain activityRelative increaseStimuli
2008
A neurology of belief
Sacks O, Hirsch J. A neurology of belief. Annals Of Neurology 2008, 63: 129-130. PMID: 18306392, DOI: 10.1002/ana.21378.Peer-Reviewed Original Research