2006
Hemodynamic Impairment as a Stimulus for Functional Brain Reorganization
Marshall RS, Krakauer JW, Matejovsky T, Zarahn E, Barnes A, Lazar RM, Hirsch J. Hemodynamic Impairment as a Stimulus for Functional Brain Reorganization. Cerebrovascular And Brain Metabolism Reviews 2006, 26: 1256-1262. PMID: 16421509, DOI: 10.1038/sj.jcbfm.9600274.Peer-Reviewed Original ResearchConceptsVasomotor reactivityHemodynamic impairmentMotor-related activityControl subjectsFunctional reorganizationMotor regionsLevel-dependent signal intensityAbnormal cerebral hemodynamicsTypical motor activitiesLarge vessel occlusionSubgroup of patientsBlood oxygen level-dependent (BOLD) signal intensityContralateral motor areasFunctional brain reorganizationCarbon dioxide inhalationSimple motor taskFunctional magnetic resonanceAbnormal vasoreactivityTranscranial DopplerBrain reorganizationVessel occlusionCerebral hemodynamicsHand contralateralMotor areaFocal lesions
2003
fMRI Evidence for Cortical Modification during Learning of Mandarin Lexical Tone
Wang Y, Sereno JA, Jongman A, Hirsch J. fMRI Evidence for Cortical Modification during Learning of Mandarin Lexical Tone. Journal Of Cognitive Neuroscience 2003, 15: 1019-1027. PMID: 14614812, DOI: 10.1162/089892903770007407.Peer-Reviewed Original ResearchConceptsLanguage-related areasSecond languageBroca's areaEmergence of activityRight inferior frontal gyrusFunctional magnetic resonance imagingMandarin lexical tonesNative English speakersInferior frontal gyrusAdditional cortical regionsSupplementary motor regionsSuperior temporal gyrusBrodmann's area 42Area 42Lexical tonesEnglish speakersTone trainingFrontal gyrusLanguage functionTemporal gyrusWernicke's areaAuditory cortexMotor regionsCortical regionsLanguage