2015
Greater anterior cingulate activation and connectivity in response to visual and auditory high-calorie food cues in binge eating: Preliminary findings
Geliebter A, Benson L, Pantazatos SP, Hirsch J, Carnell S. Greater anterior cingulate activation and connectivity in response to visual and auditory high-calorie food cues in binge eating: Preliminary findings. Appetite 2015, 96: 195-202. PMID: 26275334, PMCID: PMC4684801, DOI: 10.1016/j.appet.2015.08.009.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexHigh-calorie food cuesNon-BE groupFood cuesNeural responsesPsychophysiologic interactionsOrbitofrontal cortexFunctional connectivityGreater functional connectivityRegional brain activationAnterior cingulate activationHigh energy density foodsAnterior cingulate cortexLow-ED foodsAuditory cuesFMRI scanningActivation differencesBrain activationCingulate activationMore activationSupramarginal gyrusNeuroimaging studiesBE groupObese individualsCingulate cortexBrain activity classifies adolescents with and without a familial history of substance use disorders
Qiao J, Wang Z, Geronazzo-Alman L, Amsel L, Duarte C, Lee S, Musa G, Long J, He X, Doan T, Hirsch J, Hoven CW. Brain activity classifies adolescents with and without a familial history of substance use disorders. Frontiers In Human Neuroscience 2015, 9: 219. PMID: 25954186, PMCID: PMC4406072, DOI: 10.3389/fnhum.2015.00219.Peer-Reviewed Original ResearchAnterior cingulate cortexSubstance use disordersPrefrontal cortexEmotional conflictBrain circuitsEmotional Stroop taskPotential neurobiological mechanismsFunctional magnetic resonanceUse disordersGroup-level analysisStroop taskVentral tegmental areaNeural substratesCognitive behaviorNeurobiological mechanismsBrain activityEffective connectivityEndophenotype markersCingulate cortexBrain featuresGranger causality indexWeak connectivityFH- adolescentsAdolescentsCausal interactions
2012
The temporal derivative of expected utility: A neural mechanism for dynamic decision-making
Zhang X, Hirsch J. The temporal derivative of expected utility: A neural mechanism for dynamic decision-making. NeuroImage 2012, 65: 223-230. PMID: 22963852, PMCID: PMC5841235, DOI: 10.1016/j.neuroimage.2012.08.063.Peer-Reviewed Original ResearchConceptsNeural mechanismsBehavioral dataHuman neural correlatesNovel experimental paradigmDistinct neural activitySuperior parietal lobulePosterior cingulate cortexReal-world tasksNeural correlatesFuture rewardsParietal lobuleExperimental paradigmFMRI analysisCingulate cortexNeural activityWorld tasksBrain regionsSupplementary motorCentral gyrusDynamic decision processIndependent manipulationContinuous decisionsDecision processVentral pallidumFMRI
2006
Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala
Etkin A, Egner T, Peraza D, Kandel E, Hirsch J. Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala. Neuron 2006, 52: 1121. DOI: 10.1016/j.neuron.2006.12.003.Peer-Reviewed Original ResearchResolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala
Etkin A, Egner T, Peraza DM, Kandel ER, Hirsch J. Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala. Neuron 2006, 51: 871-882. PMID: 16982430, DOI: 10.1016/j.neuron.2006.07.029.Peer-Reviewed Original ResearchConceptsRostral anterior cingulate cortexAnterior cingulate cortexFunctional magnetic resonance imagingCingulate cortexEmotional conflictAmygdalar activityRostral cingulate cortexMagnetic resonance imagingDorsolateral prefrontal cortexRostral cingulateResonance imagingPrefrontal cortexModulating activityCortexConflict taskSalient stimuliNeural activityNeural mechanismsMental functioningActivationConflictActivityAmygdala
2005
Intentional false responding shares neural substrates with response conflict and cognitive control
Nuñez JM, Casey BJ, Egner T, Hare T, Hirsch J. Intentional false responding shares neural substrates with response conflict and cognitive control. NeuroImage 2005, 25: 267-277. PMID: 15734361, DOI: 10.1016/j.neuroimage.2004.10.041.Peer-Reviewed Original ResearchMeSH KeywordsAdultArousalAutobiographies as TopicBrainCaudate NucleusConflict, PsychologicalDeceptionDominance, CerebralFemaleGyrus CinguliHumansImage Processing, Computer-AssistedIntentionInternal-External ControlMagnetic Resonance ImagingMaleNerve NetNeural InhibitionParietal LobePersonality InventoryPrefrontal CortexReaction TimeTemporal LobeThalamic NucleiConceptsDorsolateral prefrontal cortexCognitive controlResponse conflictAnterior cingulate cortexPsychopathic Personality InventoryCingulate cortexSelf-report personality measuresSelf-relevant stimuliFalse responsesAmount of conflictPosterior cingulate cortexResponse inhibitionNeural substratesCaudate activityMesial prefrontalNeural effectsPersonality measuresCognitive functionPersonal relevancePrefrontal cortexAnterior cingulateNeural activityAutobiographical responsesProcess of interferenceResponse conditions