2021
Bidirectional Connectivity Between Broca's Area and Wernicke's Area During Interactive Verbal Communication
Ono Y, Zhang X, Noah JA, Dravida S, Hirsch J. Bidirectional Connectivity Between Broca's Area and Wernicke's Area During Interactive Verbal Communication. Brain Connectivity 2021, 12: 210-222. PMID: 34128394, PMCID: PMC9058861, DOI: 10.1089/brain.2020.0790.Peer-Reviewed Original ResearchConceptsWernicke's areaNeural mechanismsBroca's areaDirectional connectivityHealthy adult participantsHemodynamic responseBidirectional connectivityFunctional connectivityNeural modulationBrainNeuronal informationSpeech areasNeural activityAdult participantsBrocaContrast findingsHuman brainImpact statementNeural dynamicsBrain modelFindingsWernicke'sSocial functionGranger causality analysisVerbal condition
2018
A cross-brain neural mechanism for human-to-human verbal communication
Hirsch J, Noah J, Zhang X, Dravida S, Ono Y. A cross-brain neural mechanism for human-to-human verbal communication. Social Cognitive And Affective Neuroscience 2018, 13: 907-920. PMID: 30137601, PMCID: PMC6137318, DOI: 10.1093/scan/nsy070.Peer-Reviewed Original ResearchConceptsSuperior temporal gyrusInteractive brain hypothesisNeural mechanismsSocial interactionBrain hypothesisCanonical language areasHuman verbal communicationNon-interactive conditionDynamic social interactionsObject NamingSocial cuesInterpersonal informationBrain substratesDescription taskTemporal gyrusBroca's areaLanguage areasWernicke's areaNeural activitySubcentral areaVerbal communicationNatural settingsTheoretical frameworkGeneral theoretical frameworkDeoxyhemoglobin signal
2003
fMRI Evidence for Cortical Modification during Learning of Mandarin Lexical Tone
Wang Y, Sereno JA, Jongman A, Hirsch J. fMRI Evidence for Cortical Modification during Learning of Mandarin Lexical Tone. Journal Of Cognitive Neuroscience 2003, 15: 1019-1027. PMID: 14614812, DOI: 10.1162/089892903770007407.Peer-Reviewed Original ResearchConceptsLanguage-related areasSecond languageBroca's areaEmergence of activityRight inferior frontal gyrusFunctional magnetic resonance imagingMandarin lexical tonesNative English speakersInferior frontal gyrusAdditional cortical regionsSupplementary motor regionsSuperior temporal gyrusBrodmann's area 42Area 42Lexical tonesEnglish speakersTone trainingFrontal gyrusLanguage functionTemporal gyrusWernicke's areaAuditory cortexMotor regionsCortical regionsLanguage
2000
An Integrated Functional Magnetic Resonance Imaging Procedure for Preoperative Mapping of Cortical Areas Associated with Tactile, Motor, Language, and Visual Functions
Hirsch J, Ruge M, Kim K, Correa D, Victor J, Relkin N, Labar D, Krol G, Bilsky M, Souweidane M, DeAngelis L, Gutin P. An Integrated Functional Magnetic Resonance Imaging Procedure for Preoperative Mapping of Cortical Areas Associated with Tactile, Motor, Language, and Visual Functions. Neurosurgery 2000, 47: 711. PMID: 10981759, DOI: 10.1097/00006123-200009000-00037.Peer-Reviewed Original ResearchConceptsIntraoperative electrophysiological measurementsVisual field examinationVisual functionHealthy volunteersCentral sulcusVisual cortexFMRI mapsWernicke's areaFunctional magnetic resonance imaging (fMRI) taskDirect cortical stimulationFunctional magnetic resonance imaging (fMRI) procedureBroca's areaField examinationElectrophysiological measurementsSurgical patientsSurgical riskCortical stimulationPreoperative mappingSurgical routeWada testCortical areasElectrophysiological proceduresMagnetic resonance imaging (MRI) proceduresMultiple critical functionsPreoperative map
1997
Distinct cortical areas associated with native and second languages
Kim K, Relkin N, Lee K, Hirsch J. Distinct cortical areas associated with native and second languages. Nature 1997, 388: 171-174. PMID: 9217156, DOI: 10.1038/40623.Peer-Reviewed Original ResearchConceptsSecond languageFunctional magnetic resonance imagingMultiple language functionsLanguage-specific regionsCortical areasEssential human capacitiesFrontal cortical areasLanguage acquisitionNative languageBilingual subjectsMultiple languagesDistinct cortical areasLanguageLanguage functionBroca's areaCortical representationHuman capacityHuman brainHuman cortexAcquisition stageSeparation of activitiesMagnetic resonance imagingResonance imagingFundamental questionsAdulthood