2011
Differences in Regional Brain Activation Patterns Assessed by Functional Magnetic Resonance Imaging in Patients with Systemic Lupus Erythematosus Stratified by Disease Duration
Mackay M, Bussa MP, Aranow C, Uluğ AM, Volpe BT, Huerta PT, Argyelan M, Mandel A, Hirsch J, Diamond B, Eidelberg D. Differences in Regional Brain Activation Patterns Assessed by Functional Magnetic Resonance Imaging in Patients with Systemic Lupus Erythematosus Stratified by Disease Duration. Molecular Medicine 2011, 17: 1349-1356. PMID: 21953419, PMCID: PMC3321819, DOI: 10.2119/molmed.2011.00185.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusBlood-brain barrierFunctional magnetic resonance imagingTissue damageDisease durationBrain activation patternsLupus erythematosusST groupSystemic Lupus International Collaborating Clinics Damage IndexActivation patternsFearful face paradigmRegional brain activation patternsDuration of diseaseRegional brain abnormalitiesCentral nervous systemMagnetic resonance imagingFunctional magnetic resonanceCorticosteroid dosesDisease activityComorbid diseasesSLE patientsImmune cellsVascular diseaseBrain injuryBrain abnormalities
2009
Behavioral assessment in patients with disorders of consciousness: gold standard or fool's gold?
Giacino JT, Schnakers C, Rodriguez-Moreno D, Kalmar K, Schiff N, Hirsch J. Behavioral assessment in patients with disorders of consciousness: gold standard or fool's gold? Progress In Brain Research 2009, 177: 33-48. PMID: 19818893, DOI: 10.1016/s0079-6123(09)17704-x.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessMedication side effectsSevere brain injuryAssessment of patientsBehavioral assessmentCurrent diagnostic criteriaFunctional neuroimaging findingsBrain injuryInvoluntary movementsNeuroimaging findingsMotor impairmentDiagnostic criteriaSide effectsBehavioral assessment techniquesNeurophysiologic markersVegetative stateConscious stateGold standardBehavioral assessment methodsFunctional neuroimagingPatientsDisordersIndirect evidenceBehavioral markersMarkers
2007
Brain Activity Associated With Stimulation Therapy of the Visual Borderzone in Hemianopic Stroke Patients
Marshall RS, Ferrera JJ, Barnes A, Xian Zhang, O'Brien KA, Chmayssani M, Hirsch J, Lazar RM. Brain Activity Associated With Stimulation Therapy of the Visual Borderzone in Hemianopic Stroke Patients. Neurorehabilitation And Neural Repair 2007, 22: 136-144. PMID: 17698955, DOI: 10.1177/1545968307305522.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalAdultAgedAttentionBrainBrain MappingCerebrovascular CirculationFemaleFunctional LateralityHemianopsiaHumansMagnetic Resonance ImagingMaleMiddle AgedNeuronal PlasticityPhotic StimulationPhysical Therapy ModalitiesStrokeTreatment OutcomeVisual PathwaysVisual PerceptionConceptsVisual restoration therapyRestoration therapyHemianopic patientsAnterior cingulateHemianopic stroke patientsHigher-order visual areasBilateral anterior cingulateBilateral basal gangliaHome-based treatment programDorsolateral frontal cortexBlood oxygen level-dependent activityBrain activityFunctional magnetic resonance imagingMagnetic resonance imagingBrain Activity AssociatedCondition interactionLevel-dependent activityStroke patientsBasal gangliaBrain injuryStimulation therapyFrontal cortexMiddle temporal regionsRepetitive stimulationVisual therapy
2006
Cortical reorganization following intradigital tendon transfer
Viswanathan V, Chmayssani M, Adams DJ, Hirsch J. Cortical reorganization following intradigital tendon transfer. Neuroreport 2006, 17: 1669-1673. PMID: 17047451, DOI: 10.1097/01.wnr.0000239953.60695.08.Peer-Reviewed Original Research
2005
Functional neuroimaging during altered states of consciousness: how and what do we measure?
Hirsch J. Functional neuroimaging during altered states of consciousness: how and what do we measure? Progress In Brain Research 2005, 150: 25-590. PMID: 16186013, DOI: 10.1016/s0079-6123(05)50003-7.Peer-Reviewed Original ResearchConceptsCognitive processesFunctional neuroimagingDisorders of consciousnessPassive stimulationLanguage-related tasksFunctional magnetic resonanceSpecific traumatic eventStudy of consciousnessFunctional brain activityAltered statesAffective systemsCognitive systemNeural processesTraumatic eventsNeurocognitive healthBrain activitySensory-motor functionParadigm selectionMotor systemVolitional tasksCortical functionExperimental manipulationTaskBrain injuryTemporal sequence