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Henry J. Binder, MD

Professor Emeritus of Medicine (Digestive Diseases)
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Contact Info

Yale School of Medicine

Department of Medicine (Digestive Diseases), PO Box 208019

New Haven, CT 06520-8019

United States

About

Titles

Professor Emeritus of Medicine (Digestive Diseases)

Appointments

Other Departments & Organizations

Education & Training

Postdoctoral Fellow
Yale University School of Medicine (1965)
Intern/Resident
Bellevue Hospital, New York University (1963)
MD
New York University (1961)
BA
Dartmouth College (1957)

Research

Overview

Dr. Binder's research career has primarily been directed toward the regulation of colonic electrolyte transport and the pathophysiology of diarrhea and the basis for development of new approaches for treatment of diarrhea. These transport studies were primarily in vitro and dissected the cellular mechanisms of Na, C1, K, HCO3 and short-chain fatty acid transport and were supported by NIDDK for 37 years. During the past few years, Dr. Binder has focused his investigative activities toward the establishment of a major modification of oral rehydration solution (ORS) that is based on his prior laboratory studies that demonstrated butyrate-stimulated Na absorption in the colon was cyclic AMP-insensitive. These studies supported by Bill & Melinda Gates Foundation are designed to increase the uptake of ORS with the adaption of an improved formulation with resistant starch (starch that is relatively insensitive to amylase digestion).

Medical Subject Headings (MeSH)

Adenosine Triphosphatases; Digestive System Diseases; Epithelial Cells; Fatty Acids, Volatile; Ion Transport

Research at a Glance

Yale Co-Authors

Frequent collaborators of Henry J. Binder's published research.

Publications

2014

2013

2012

2011

2010

2009

Academic Achievements & Community Involvement

  • activity

    Diarrhea and Oral Rehydration Therapy

Get In Touch

Contacts

Academic Office Number
Office Fax Number
Mailing Address

Yale School of Medicine

Department of Medicine (Digestive Diseases), PO Box 208019

New Haven, CT 06520-8019

United States

Administrative Support