Discovery may help provide clues for fighting and treating HPV
Yale Cancer Center (YCC) scientists have filled in a key gap in understanding the unusual route by which the Human papillomavirus (HPV) infects cells. Their findings, published online today in the journal Cell, may eventually help to broaden the scope of defenses against HPV and provide valuable clues for delivering drugs into cells. HPV is a family of killers. Although there are effective vaccines against these viruses, they still cause about 5% of cancer deaths worldwide, including more than 250,000 women who die of cervical cancer each year.
New Simple Proteins Play Active Role in Cellular Function
Yale scientists have developed simple new proteins almost devoid of chemical diversity that still play a surprisingly active and specific role in cellular function, causing cells to act like cancer cells, they report Aug. 10 in the Proceedings of the National Academy of Sciences.
Two Yale Stem Cell Center members, Daniel DiMaio and Laura Niklason, have been elected to the Connecticut Academy of Science and Engineering.
Two Yale Stem Cell Center members, Daniel DiMaio and Laura Niklason, have been elected to the Connecticut Academy of Science and Engineering.Source: Connecticut Academy of Science and Engineering
New proteins inhibit HIV infection in cell cultures
Yale Cancer Center scientists have developed a new class of proteins that inhibit HIV infection in cell cultures and may open the way to new strategies for treating and preventing infection by the virus that causes AIDS. The findings appear in the online edition of the Journal of Virology.
The war on AIDS: Newly Developed Proteins Inhibit HIV Infection
Yale Cancer Center scientists have developed a new class of proteins that inhibit HIV infection and may open the way to new strategies for treating and preventing infection by the virus that causes AIDS. The findings appear in the July 18 online edition of the Journal of Virology.
Daniel C. DiMaio, M.D., Named Scientific Director of Yale Cancer Center
Yale Cancer Center Director Dr. Richard L. Edelson announced the appointment of Daniel DiMaio, M.D., PhD, to Scientific Director of the Center. In this role, DiMaio will have broad oversight of all basic science research within Yale Cancer Center (YCC).Source: Yale Office of Public Affairs and Communications
$7.5 Million Grant to Yale Researchers for Role of Viruses in Cancer
The National Cancer Institute recently awarded a five-year, $7.5 million program project grant to investigators at the Yale School of Medicine to continue studies on the role of viruses and mutant cellular proteins in tumorigenic transformation of cells.
Work by Desai Referenced in Groundbreaking Report
The work and contributions of Miraj Desai, PhD, assistant professor of psychiatry, were referenced multiple times in the groundbreaking report, "Racism in the U.S. Health System: The Transformation We Need," led by the Robert Wood Johnson Foundation (RWJF), with consultation support from CoCreative.
Review: Clinical Trial Design Challenges and Opportunities for Emerging Treatments for Opioid Use Disorder
Brian D. Kiluk, PhD, associate professor of psychiatry, is first author of a review in JAMA Psychiatry that highlights unique clinical trial design considerations for the study of emerging treatments for opioid use disorder that address targets beyond the endogenous μ-opioid receptor system.Source: JAMA Psychiatry
Durkheim’s Theory of Social Integration and Suicide Revisited: Is It Diversity of Social Networks or Perceived Strength of Social Support That Matters?
Peter Na, MD, MPH; Tanner Bommersbach, MD, MPH; Robert Pietrzak, PhD, MPH; and Greg Rhee, PhD, are authors of a paper in The Journal of Clinical Psychiatry that found greater diversity of social networks was more strongly associated with lower risks of suicidal ideation and attempt than perceived strength of social support.Source: The Journal of Clinical Psychiatry
Grant Will Help Yale Team Develop Diagnostic Tool to Evaluate Tumors
The Yale Center for Clinical Investigation (YCCI) has awarded a research pilot award to an interdisciplinary team of Yale researchers for a project titled, “Utilizing Machine Learning to Model the Volumetric Growth of Vestibular Schwannomas.”
Study: Alzheimer's Drug Shows Modest Success Slowing Declines in Memory, Thinking
Christopher Van Dyck, MD, professor of psychiatry and director of the Alzheimer's Disease Research Unit, spoke about an experimental drug for Alzheimer's disease patients at the Clinical Trials on Alzheimer's Disease meeting in San Francisco in November.Source: NPR
Provision of Mental Health Services in the Veterans Health Administration: A Nationwide Comparison With Other Providers
On average, Veterans Health Administration (VHA) mental healthcare facilities offer significantly more treatment modalities, specialized services, and dedicated treatment programs than non-VHA facilities, according to a new study by Yale Psychiatry researchers published online in Psychiatric Services.
Yale Study Seeks to Understand Neurobiology Underlying Bipolar Disorder Vs. Major Depressive Disorder
Yale scientists, including Sophie Holmes, PhD; Ruth Asch, PhD; and Irina Esterlis, PhD, used positron emission tomography to understand the neurobiology underlying bipolar disorder versus major depressive disorder. The findings were published in Biological Psychiatry.Source: Biological Psychiatry
Cook, Simiola Awarded PCORI Grant
Joan Cook, PhD, professor of psychiatry, and Vanessa Simiola, research assistant, have been awarded a Patient-Centered Outcomes Research Institute grant to implement written exposure therapy for posttraumatic stress disorder in six civilian health care systems across the United States.Source: Patient-Centered Outcomes Research Institute